Calcium propionate

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Structural formula
Calcium ion Propionation
Surname Calcium propionate
other names
  • Calcium dipropionate
  • E  282
Molecular formula C 6 H 10 CaO 4
Brief description

colorless solid

External identifiers / databases
CAS number 4075-81-4
EC number 223-795-8
ECHA InfoCard 100,021,633
PubChem 19999
ChemSpider 18840
Wikidata Q417394
Molar mass 186.22 g mol −1
Physical state


Melting point

> 300 ° C

  • good in water (260 g l −1 at 20 ° C)
  • poorly soluble in ethanol
safety instructions
GHS labeling of hazardous substances
no GHS pictograms
H and P phrases H: no H-phrases
P: no P-phrases
Toxicological data
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Calcium propionate is an odorless, colorless salt of propionic acid in its pure form with the empirical formula C 6 H 10 CaO 4 . Calcium propionate decomposes at around 300 ° C. If the compound contains unreacted propionic acid from the production process, it has a pungent odor. The fungistatic inhibits the growth of fungi and is used as a preservative (E 282) in food - especially for bread and other baked goods . Calcium propionate is also used in cosmetics or as a feed additive to compound feed .


Calcium propionate is obtained in a direct synthesis; here calcium oxide and calcium hydroxide are placed in a mixer and reacted with propionic acid. Pure calcium hydroxide could also be used, but since water is formed as a by-product, calcium oxide can be used, which reacts with the water to form calcium hydroxide. Excess water is evaporated under negative pressure (0.6 to 0.95 bar ) at approx. 70–90 ° C.

Calcium oxide and propionic acid react when heated and under pressure to form calcium propionate and water

Sub-steps of the reaction:



Calcium propionate crystallizes as a monohydrate, which releases its water of crystallization at 100 ° C. It decomposes at 350 - 450 ° C with the formation of calcium carbonate .

safety instructions

With prolonged administration of propionic acid and propionates in the feed of rats in doses between 0.6 and 5%, these cause changes in the forestomach ( thickening and inflammation). However, this is classified as a species-specific reaction for rats, since no such effects were observed in other animal species such as mice and rabbits.

See also

Individual evidence

  1. Entry on E 282: Calcium propionate in the European database for food additives, accessed on June 27, 2020.
  2. Entry on CALCIUM PROPIONATE in the CosIng database of the EU Commission, accessed on February 24, 2020.
  3. ^ A b Richard J. Lewis, Sr .: Hawley's Condensed Chemical Dictionary . 15th edition. Wiley-Interscience, 2007, ISBN 978-0-471-76865-4 (English).
  4. a b c data sheet Calcium propionate hydrate, 97% from AlfaAesar, accessed on December 7, 2019 ( PDF )(JavaScript required) .
  5. Data sheet calcium propionate from Acros, accessed on February 24, 2013.
  6. a b Kenkyu Nenpo - Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. Vol. 27, Pg. 159, 1976.
  7. a b Entry on calcium propionate in the ChemIDplus database of the United States National Library of Medicine (NLM) .
  8. ^ A. Renard: "Sur les propionates métalliques" in Comptes rend. hebd. 1887 , 104 , pp. 913-917. Full text
  9. CA O'Connell, D. Dollimore: "A study of the decomposition of calcium propionate, using simultaneous TG-DTA" in Thermochimica Acta 2000 , 357-358 , pp. 79-87. doi : 10.1016 / S0040-6031 (00) 00371-3
  10. ^ AK Galwey, ME Brown: Thermal Decomposition of Ionic Solids: Chemical Properties and Reactivities of Ionic Crystalline Phases . Elsevier, 1999, ISBN 0-08-054279-4 , pp. 451 ( limited preview in Google Book search).
  11. H.-G. Classen, PS Elias, WP Hammes, M. Winter: Toxicological-hygienic assessment of food ingredients and additives. Behr's Verlag, 2001, ISBN 978-3-86022-806-7 .