Estriol
Structural formula | |||||||||||||||||||
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General | |||||||||||||||||||
Surname | Estriol | ||||||||||||||||||
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Molecular formula | C 18 H 24 O 3 | ||||||||||||||||||
Brief description |
Colorless crystals |
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properties | |||||||||||||||||||
Molar mass | 288.37 g · mol -1 | ||||||||||||||||||
Physical state |
firmly |
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Melting point |
282-285 ° C |
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solubility |
soluble in organic solvents and vegetable oils, practically insoluble in water |
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Toxicological data | |||||||||||||||||||
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
Estriol (E 3 ), also known as estriol , is a quantitatively important metabolic product of estradiol and estrone . It has a weak estrogenic effect, about 1/10 that of estradiol. It is formed in the placenta directly or from precursors synthesized by the fetus . Estriol is also produced in adipose tissue by aromatizing the A-ring of androstenedione .
Trade names
OeKolp (D), Oestro-Gynaedron (D, CH), Ortho-Gynest (D, A, CH), Ovestin (D, A, CH), Xapro (D), Generika (D)
CycloÖstrogynal (D), Gynoflor (D, A, CH)
Individual evidence
- ↑ a b c Entry on estriol. In: Römpp Online . Georg Thieme Verlag, accessed on December 28, 2014.
- ↑ a b sheet estriol at Sigma-Aldrich retrieved on October 18, 2016 ( PDF ).
- ↑ Entry on estriol in the ChemIDplus database of the United States National Library of Medicine (NLM) .