Halosulfuron-methyl

Structural formula
General
Surname	Halosulfuron-methyl
other names	Methyl 3-chloro-5 - [({[(4,6-dimethoxypyrimidin-2-yl) amino] carbonyl} amino) sulfonyl] -1-methyl-1 H -pyrazole-4-carboxylate
Molecular formula	C 13 H 15 ClN 6 O 7 S
Brief description	White dust
External identifiers / databases
CAS number 100784-20-1 EC number 600-130-3 ECHA InfoCard 100.117.125 PubChem 91763 ChemSpider 82861 Wikidata Q22808250
properties
Molar mass	434.81 g mol
Physical state	firmly
density	1.618 g cm −3
Melting point	176 ° C
boiling point	181.6 ° C
solubility	practically insoluble in water (10.2 g l −1 at 20 ° C)
safety instructions
GHS labeling of hazardous substances danger H and P phrases H: 360D-410 P: ?
Toxicological data	8865 mg kg −1 ( LD 50 ,  rat ,  oral )
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Halosulfuron-methyl is an active ingredient in crop protection and belongs to the class of sulfonylurea herbicides . It is a white solid.

history

Halosulfuron-methyl was developed by Monsanto and introduced in the mid-1990s.

effect

Halosulfuron-methyl is a selective herbicide . It is absorbed via the roots and leaves and transported further in the plant. The active ingredient acts as an ALS inhibitor . Here, the biosynthesis of the amino acids L -isoleucine and L -valine , ie of two essential amino acids , inhibited . This inhibits cell division , so that growth comes to a standstill. Ultimately, the plants fade and necrosis forms , which is why the weeds die.

use

It is mainly used against broad-leaved weeds in corn, rice and sugar cane crops.

Environmental aspects

Halosulfuron-methyl is not toxic to bees, but is chronically hazardous to the aquatic environment . The degradation takes place through hydrolytic cleavage of the sulfonylurea group with a half-life of less than three weeks.

proof

Residues can be determined in plants and soils using the HPLC method .

Admission status

In Germany there are none so far pesticides admitted that this active ingredient contained. Halosulfuron-methyl may be used in the EU .

Individual evidence

1. ↑ ^{a b c d e f} Entry on Halosulfuron-methyl in the GESTIS substance database of the IFA , accessed on July 7, 2020(JavaScript required) .
2. ↑ Data sheet Halosulfuron-methyl from Sigma-Aldrich , accessed on July 7, 2020 ( PDF ). .
3. ↑ ^{a b c d e f g} Entry on Halosulforon-methyl. In: Römpp Online . Georg Thieme Verlag, accessed on July 7, 2020.
4. ^ Directorate-General for Health and Food Safety of the European Commission: Entry on Halosulfuron - methyl in the EU pesticide database; accessed on July 10, 2020.