Hans-Reimer Rodewald

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Hans-Reimer Rodewald (born April 10, 1958 in Hamburg ) is a German immunologist at the German Cancer Research Center in Heidelberg . He is considered one of the world's leading immunologists. The focus of his research is the question of how different immune cells develop from stem cells in the body , which form and maintain a functioning immune system .

Live and act

Rodewald studied at the Foundation School of Veterinary Medicine and graduated in 1983 with the work A study of the repertoire of regulatory and cytotoxic T lymphocytes of the mouse: correlations between the structure and function of the T cell antigen receptor with the doctor in veterinary medicine from . In 1988 he obtained at the Max Planck Institute of Immunobiology in Freiburg one Dr. phil. in immunology. As a postdoctoral fellow he worked at the Max Planck Institute for Immunobiology, in 1988/1989 at the Cancer Center of the Massachusetts Institute of Technology (MIT) and then at the Dana-Farber Cancer Institute , before joining the Basel Institute for Immunology in 1992 . In 1996/1997 he completed his habilitation with the thesis differentiation pathways from hematopoietic stem cells to T lymphocytes and natural killer cells . In 1999 Rodewald received a C4 professorship at the Institute for Immunology at Ulm University . Since 2010 he has headed the department for cellular immunology at the German Cancer Research Center in Heidelberg .

Rodewald focus of the work is the production and analysis of mouse mutants with changes in hematopoiesis and immunology , for example, viable KIT -null mutants with the aid of insights into the role of this stem cell - receptor were possible in adult tissues. Rodewald developed mutants to uncover the function of mast cell - proteases . Further mutants allow insights into the development pathways from stem cells to mast cells and basophils . In his thymus research, Rodewald concentrated on methods for introducing mutations into the thymus epithelial cell , where he succeeded in discovering a second, functional thymus in the neck of mice.

Honors

Web links

Individual evidence

  1. ^ Vita: Members of the Leopoldina , leopoldina.org, .pdf, p. 38.
  2. a b Agnes Giniewski: Hans-Reimer Rodewald receives the German Immunology Prize of DGfI. German Society for Immunology, press release from September 28, 2016 at Informationsdienst Wissenschaft (idw-online.de), accessed on October 30, 2016.
  3. DNB 890940649
  4. DNB 950492094
  5. ^ Member entry by Hans-Reimer Rodewald (with picture) at the German Academy of Sciences Leopoldina , accessed on January 11, 2017.
  6. 58 life science researchers elected as new EMBO members. In: embo.org. May 23, 2016, accessed October 30, 2016 .
  7. Immunologist Hans-Reimer Rodewald receives a Leibniz Prize , Der Tagesspiegel from December 6, 2018, accessed December 6, 2018