Hans Reichenbach (microbiologist)

Hans Reichenbach (born October 10, 1936 in Karlsruhe ; † November 2, 2018 in Wolfenbüttel ) was a German microbiologist and natural product biologist.

Live and act

Structural formula for epothilone A or B

Reichenbach studied biology , chemistry and geography in Karlsruhe, Kiel, Munich and Freiburg. In 1961 he passed the state examination in Freiburg, and in 1965 he received his doctorate in Karlsruhe. From 1966 to 1968 he worked as a postdoctoral fellow with M. Dworkin in Minneapolis , Minnesota and in Morgantown. From 1968 to 1975 he was a research assistant to Gerhart Drews at the Albert-Ludwigs-Universität Freiburg , where Reichenbach completed his habilitation in general microbiology in 1971 .

Since 1975 Reichenbach was employed by the Society for Biotechnological Research in Braunschweig (today the Helmholtz Center for Infection Research ). There he was head of the department for microbiology until 1984, from 1994 of the department for biology of natural products . Since 1976 he was an adjunct professor at the University of Braunschweig . In 2001 he retired.

Reichenbach described various taxa , including the Flavobacteriaceae , Cytophaga aprica and Flexibacter elegans .

Together with Gerhard Höfle , he systematically investigated secondary metabolites of numerous bacteria, including myxobacteria . In doing so, he discovered the first epothilone , a substance from a group of 16-membered macro lactones, in the myxobacterium Sorangium cellulosum . The substance class has an effect on tumor cells analogous to that of paclitaxel , which is why it is used in cancer research and cancer therapy.

Publications

• The Flavobacterium-Cytophaga group , Society for Biotechnological Research (editor), Weinheim, Verlag Chemie 1981
• In Encyclopaedia Cinematographica : E 777: Archangium violaceum (Myxebacteriales) - swarm development and formation of protocysts , Göttingen 1968, Institute for Scientific Film

Awards (selection)

• 2004 Karl Heinz Beckurts Prize (together with Gerhard Höfle )
• 2006 Inhoffen Medal from the Helmholtz Center for Infection Research (together with Gerhard Höfle)

1. ↑ Not to be confused with the Hans Herloff Inhoffen Prize of the Society of German Chemists .

literature

• Hans Reichenbach, microbiologist: Der Marathon-Mann , in: Brand eins 04/2014, p. 156 ff

Individual evidence

1. ↑ Obituary notice. In: Braunschweiger Zeitung. November 9, 2018. Retrieved November 9, 2018 . 
2. ↑ ^{a b} HZI research report 2006/2007  ( page no longer available , search in web archives )  Info: The link was automatically marked as defective. Please check the link according to the instructions and then remove this notice. (PDF, 8.3 MB), p. 59; Retrieved April 1, 2014  
3. ↑ New active ingredient against cancer. ( Memento of the original from April 7, 2014 in the Internet Archive ) Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. Helmholtz Association of German Research Centers (helmholtz.de); Retrieved April 1, 2014 
4. ↑ Happy Odyssey of Research: From Myxobacterium to Cancer Drug. ( Memento of the original from March 4, 2016 in the Internet Archive ) Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. biotechnologie.de; Retrieved April 1, 2014 
5. ↑ 2004 award winner from the Karl Heinz Beckurts Foundation (beckurts-stiftung.de); Retrieved April 1, 2014
6. ↑ Cancer drug from the compost heap: Myxobacteria researchers from GBF awarded the Beckurts Prize. Press release from December 7, 2004 at the Informationsdienst Wissenschaft (idw-online.de)
7. ↑ Inhoffen Medal from the Helmholtz Center for Infection Research (helmholtz-hzi.de); Retrieved April 1, 2014