Hermann Druckrey

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Hermann Druckrey

Hermann Druckrey (born July 27, 1904 in Greifswald , † August 7, 1994 in Freiburg im Breisgau ) was a German pharmacologist , toxicologist and oncologist .

Life

Hermann Druckrey was born as the son of the Greifswald pharmacist Otto Druckrey and his wife Dorothea. Bettermann born. One cousin is Karl August Bettermann .

School and study

Hermann Druckrey attended the humanistic Melanchthong high school in Quedlinburg , where he graduated from high school in 1923. He studied medicine in Giessen , Heidelberg and Leipzig and was a member of the Corps Starkenburgia and the Corps Saxo-Borussia Heidelberg . In 1931 he passed the medical state examination in Leipzig.

Prague, Göttingen

In the same year he joined the NSDAP and the SA , in which he became Oberführer . He began his scientific training as an assistant at the Institute for Experimental Pathology at Karl Ferdinand University .

From Prague he moved to the Chemical Institute of the University of Göttingen , where he worked under Adolf Butenandt and Adolf Windaus .

As a committed corps student , Druckrey became adjutant to Max Blunck , who attended the aoKC on 14./15. January 1933 in Greifswald had been elected as the new "Leader of the KSCV and VAC". Frankonia Prag awarded him the ribbon in 1933 for his work for the Corps in Czechoslovakia in his function as head of the main office for border and foreign countries of the KSCV.

Berlin, Eastern Front, Vienna

From Göttingen he went to the Pharmacological Institute of the Friedrich Wilhelms University in Berlin . In 1936 he received his habilitation in pharmacology . He became a lecturer under Wolfgang Heubner and joined the National Socialist German Lecturer Association . In 1942 he was appointed associate professor.

In 1943/1944 Druckrey was a medical officer in an SS police regiment on the Eastern Front . After that he was director of the Pharmacological Institute of the Police Hospital Vienna VII until the end of the war .

The American science historian Robert N. Proctor formulated an ambivalent assessment of Druckrey's work in this phase: "Hermann Druckrey was an ardent Nazi [..] and a very good scientist."

After the Second World War he was interned because of his NSDAP and SA membership . He was housed in the American prison camp in Hammelburg in Lower Franconia for a long time. There he met Karl Küpfmüller , which resulted in a scientific collaboration. In July 1947, Adolf Butenandt made an affidavit in favor of Druckreys to get him released.

Freiburg

In 1948 Druckrey went to the University of Freiburg , where he was professor and laboratory manager at the University Surgical Clinic until 1964. From 1952 to 1974 he worked in the German Research Foundation (DFG) as chairman of the dye commission. In addition, from 1964 to 1973 he headed the DFG Institute for Preventive Medicine in Freiburg.

Scientific importance

Druckrey has produced over 300 scientific publications. He discovered the carcinogenic effects of a number of chemical substances; especially in the group of nitrosamines . Together with the mathematically experienced electrical and communications engineer Karl Küpfmüller , Druckrey developed the theoretical basis for the dose-effect relationship in pharmacology and toxicology, which were published in two articles in 1948 and 1949 (the Druckrey-Küpfmüller publications ). These findings were made possible by an interdisciplinary research approach and the intensive cooperation between the two, which was ultimately due to the joint internment. The Druckrey-Küpfmüller equation is named after both . He discovered the principle of the summation effect, which plays a central role in carcinogenic substances.

Honors

Publications (selection)

  • H. Druckrey and D. Schmähl: Light-dependence of fluorescence of solutions of cigarette smoke. In: Science 122, 1955, 3170 Sep 30; 122 (3170): 593. PMID 17776601 .
  • H. Druckrey: Carcinogens Alkylating Substances. Chemical constitution and effects. In: Angewandte Chemie 82, 1970, p. 777.
  • H. Druckrey: Chemotherapy of Cancer - Experimental Bases. 33, 1955.
  • H. Druckrey: Quantitative aspects in chemical carcinogenicity. In: Potential Carcinogenic Hazard from Drugs. Evaluation of Risk Volume 7, Springer-Verlag, 1967, pp. 60-78.
  • H. Druckrey and K. Küpfmüller: Quantitative analysis of the development of cancer. In: Journal of Nature Research B . 3, 1948, pp. 254–266 ( PDF , free full text).

literature

  • P. Bannasch : In memoriam Herrmann Druckrey. In: Journal of Cancer Research and Clinical Oncology 121, 1995, pp. 629-630. PMID 7593125 .
  • To Hermann Druckrey on the occasion of his 80th birthday. In: Journal of Cancer Research and Clinical Oncology 108, 1984, pp. 1-2. doi : 10.1007 / BF00390965
  • E. Boyland: In honor of Professor Hermann Druckrey's 70th birthday. In: Arzneimittel-Forschung 14, 1964, p. 845. PMID 4608802 .
  • N. Brock: On the 60th birthday of Professor Dr. Herman Druckrey. In: Arzneimittelforsch 23, 1974, pp. 845-847. PMID 14344730 .
  • P. Bannasch In: Arzneimittelforsch 29, 1979, p. 1199.
  • anonymous: 70th anniversary of Prof. Dr. Hermann Druckrey, July 27, 1974. In: Zeitschrift für Krebsforschung und Klinische Onkologie 81, 1974, pp. 179-180. PMID 4279513 .
  • P. Kleihues, P. Magee: Hermann Druckrey. In: Eur J Cancer Prev 3, 1994, pp. 391-392. PMID 8000306 .
  • Volker Wunderlich: "Substances capable of self-reproduction" as cellular targets for chemical cancerogens. In: NTM Journal for the History of Science, Technology and Medicine 15, 2007, pp. 271–283.
  • Volker Wunderlich: "With paper, pencil and slide rule". The cancer researcher Hermann Druckrey in the Hammelburg internment camp (1946–1947) , in: Medizinhistorisches Journal, Vol. 43, H. 3/4 (2008), pp. 327–343.

Web links

Individual evidence

  1. ↑ a b c d e Ernst Klee : The dictionary of persons on the Third Reich. Who was what before and after 1945 . Fischer Taschenbuch Verlag, Second, updated edition, Frankfurt am Main 2005, p. 120.
  2. ↑ Entry in the archive portal of the Kösener and Weinheimer Corps
  3. ↑ Kösener Corpslisten 1960, 37 , 752; 66 , 1459; 121 , 144.
  4. ↑ Later he laid down the Franconian ribbon; KCL 1996, 42 , 91.
  5. ^ Robert N. Proctor: The Nazi War on Cancer . Princeton 1999, p. 255.
  6. ^ Heiko Stoff: Adolf Butenandt in the post-war period, 1945–1946 . In: Wolfgang Schieder, Achim Trunk: Adolf Butenandt and the Kaiser Wilhelm Society. 2004, p. 396.
  7. ^ V. Wunderlich: On the genesis of the Druckrey-Küpfmüller-Schriften (1948–1949): Dose and effect of carcinogenic substances. In: Medizinhist J 40, 2005, pp. 369-397. PMID 16382692 .
  8. ^ Hermann Druckrey and Karl Küpfmüller: Quantitative analysis of cancer development. In: Journal of Nature Research B . 3, 1948, pp. 254–266 ( PDF , free full text).
personal data
SURNAME Druckrey, Hermann
BRIEF DESCRIPTION German pharmacologist, toxicologist and oncologist
DATE OF BIRTH July 27, 1904
PLACE OF BIRTH Greifswald
DATE OF DEATH August 7, 1994
Place of death Freiburg in Breisgau