Isotianil

Structural formula
General
Surname	Isotianil
other names	3,4-dichloro-2'-cyano-1,2-thiazole-5-carboxanilide; 3,4-dichloro- N - (2-cyanophenyl) -5-isothiazole carboxamide;
Molecular formula	C 11 H 5 Cl 2 N 3 OS
Brief description	white powder with a characteristic odor
External identifiers / databases
EC number	619-682-1
ECHA InfoCard	100.122.317
PubChem	9796266
Wikidata	Q19286298
properties
Molar mass	298.15 g mol −1
Physical state	firmly
Melting point	193-195 ° C
Vapor pressure	2.36 × 10 −7 Pa (25 ° C)
solubility	practically insoluble in water (0.5 mg l −1 at 20 ° C)
safety instructions
H and P phrases	H: 302-319-334
	P: 261-305 + 351 + 338-342 + 311
Toxicological data	> 2000 mg kg −1 ( LD 50 , rat , oral ) ; > 2000 mg kg −1 ( LD 50 , rat , transdermal ) ;
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Isotianil is a chemical compound from the group of anilides and thiazoles .

Extraction and presentation

Isotianil can be obtained by reacting 3,4-dichloro-isothiazole-5-carboxylic acid with thionyl chloride and then coupling with 2-cyanoaniline .

properties

Isotianil is a white solid with a characteristic odor.

use

Isotianil is used as a fungicide in rice against Magnaporthe grisea . The compound was discovered in 1997 by Bayer AG , investigated together with Sumitomo Chemical and brought onto the market in Japan and Korea in 2010.

No plant protection products containing this active ingredient are permitted in the EU or Switzerland .

Individual evidence

↑ ^a ^b ^c ^d ^e Isotianil data sheet from Sigma-Aldrich , accessed on May 21, 2017 ( PDF ).

↑ ^a ^b ^c Sumitomo: Applied Development of a Novel Fungicide Isotianil , accessed December 26, 2014.

↑ Entry on Isotianil in the Pesticide Properties DataBase (PPDB) of the University of Hertfordshire , accessed on December 26, 2014.

^ ^A ^b Ulrich Schirmer, Peter Jeschke, Matthias Witschel: Modern Crop Protection Compounds: Herbicides . John Wiley & Sons, 2012, ISBN 978-3-527-32965-6 , pp. 919 ( limited preview in Google Book search).

↑ General Directorate Health and Food Safety of the European Commission: Entry on Isotianil in the EU pesticide database ; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on February 14, 2016.

[Sigma-1] Isotianil data sheet from Sigma-Aldrich , accessed on May 21, 2017 ( PDF ).

[Sumitomo-2] Sumitomo: Applied Development of a Novel Fungicide Isotianil , accessed December 26, 2014.

[3] Entry on Isotianil in the Pesticide Properties DataBase (PPDB) of the University of Hertfordshire , accessed on December 26, 2014.

[Ulrich_Schirmer,_Peter_Jeschke,_Matthias_Witschel-4] A ^b Ulrich Schirmer, Peter Jeschke, Matthias Witschel: Modern Crop Protection Compounds: Herbicides . John Wiley & Sons, 2012, ISBN 978-3-527-32965-6 , pp. 919 ( limited preview in Google Book search).

[PSM-5] General Directorate Health and Food Safety of the European Commission: Entry on Isotianil in the EU pesticide database ; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on February 14, 2016.