Jochen HH Ehrich

from Wikipedia, the free encyclopedia

Jochen HH Ehrich (born January 5, 1946 in Braunschweig ) is a German pediatrician specializing in pediatric nephrology and tropical medicine , as well as a professor emeritus and former director of the Clinic for Pediatric Kidney, Liver and Metabolic Diseases at the Hannover Medical School .

Life

Ehrich began studying medicine at the Free University of Berlin in 1965 . From 1968 to 1969 he was a scholarship holder of the German Academic Exchange Service at the University of Lausanne in Switzerland and worked at the same time with Georges Peters in renal pharmacology. In 1971 he passed his state examination at the Free University of Berlin and received his doctorate there in 1972 under Klaus Hierholzer .

In 1971 he started as a medical assistant in internal medicine at the Bernhard Nocht Institute for Ship and Tropical Diseases at W. Mohr, Hamburg. From 1971 to 1972 he was a DAAD scholar at the London School of Hygiene and Tropical Medicine , London, England, where he received the Diploma in Clinical Medicine of the Tropics from the University of London (DCMT) in 1972.

At the end of 1972 he became a medical assistant in trauma surgery with Harald Tscherne and abdominal and transplant surgery with Rudolf Pichlmayr at the Hannover Medical School , from 1972 to 1973 he was medical assistant with Jan Brod in the "Experimental Nephrology" department of the "Internal Medicine" department of the MHH.

He received his license to practice medicine in March 1973. From 1973 to 1974 he was a research assistant in the pediatric nephrology department of Johannes Brodehl's pediatric clinic at the MHH.

He interrupted his further training as a pediatrician and from 1974 to 1975 did his military service as deputy military area hygienist of Military Area II in the Sanitary Department of Military Area Command II , Hygiene Department in Hanover .

From 1975 to 1979 he continued his work as a scientific assistant in the children's clinic of the MHH. In July 1979 he was recognized as a specialist in paediatrics . From 1979 to 81 he was a scholarship holder of the Volkswagen Foundation with the research assignment on "Cooperative studies for the treatment of nephrotic syndrome" at the children's clinic of the MHH. On February 4, 1981 he received the venia legendi for pediatrics.

On June 10, 1985 he was appointed adjunct professor for paediatrics at the MHH. From 1982 to 1993 he was a senior physician in Department II of the Pediatric Center at MHH.

On February 1, 1994, he was appointed C 3 Professor of Pediatrics, Department of Pediatric Ephrology at the Charité , Humboldt University of Berlin, and on October 1, 1997, he was appointed C 4 Professor of Pediatrics, Department of Pediatric Kidney and Metabolic Diseases of the Hannover Medical School. On May 31, 2011, he retired from the MHH.

In 2012 Ehrich was visiting professor at the Scientific Center of Children's Health in Moscow , Russia. From the end of 2012 to the beginning of 2013 he worked as the head of the Pediatric Nephrology Working Group at the University Children's Hospital in Innsbruck , Austria.

Clinical focus

The department at the MHH headed by Jochen HH Ehrich from 1997 to 2011 was assigned to three working groups:

  • pediatric nephrology and endocrinology, including diabetology
  • Pediatric hepatology and gastroenterology as well as sonography (the focus of the first two working groups is on transplant pediatrics, i.e. 650 kidney transplants from 1971 to 2010 and 500 liver transplants from 1982 to 2010)
  • neurometabolic working group with a focus on pediatric metabolic diseases, neuropediatrics and child psychology, and hospital school, employment department and dietitians.

Research areas

Basic research

The kidneys have been at the center of research since 1967 . At the Institute for Physiology at the Free University of Berlin, investigations into the effect of diuretics on the sodium-potassium ATPase of the plasma-membranous fraction of the rat tubule began - while still studying . In 1968 the animal experiments at the Institute of Pharmacology in Lausanne continued with a bioessay on the effect of renin - angiotensin on blood pressure .

Translational tropical medicine research on kidney involvement

The concept of our own tropical medicine research at that time was based on the hypothesis that tropical diseases are a fundamental model character for kidney involvement in all, i. H. could also have European infectious diseases . At the Tropical Institute in Hamburg, Ehrich began long-term animal experimental and clinical research into the effects of malaria on the kidneys, which later also became his habilitation topic.

At the London Tropical Institute - together with Alister Voller and Michael Hutt - an animal model for malaria-induced glomerulonephritis was developed, which was later followed up for over ten years at the children's clinic of the MHH together with Bernd Sterzel. This led to a better understanding of the life-threatening, multiple organ failure in malaria, in which kidney failure plays a key role. As a result, a Germany-wide study on the causes of death from malaria was carried out in collaboration with Rolf Horstmann, the results of which led to improved intensive medical care for critically ill people returning from the tropics in Germany. As a result, the mortality decreased significantly. But not all research directions on malaria were rewarded with the same success. For example, the tests in Helmut Deicher's laboratory did not confirm the expected nephritogenic effects of malaria-induced immune complexes .

All results on “Malaria and Kidneys” were summarized in a 2007 review article, in which a distinction was made between facts and hypotheses. The myth of the malaria-induced nephrotic syndrome in Africa - the so-called "tropical nephropathy" - has been refuted by our own research. The German Research Foundation and the Collaborative Research Center (SFB) have supported experimental research for many years.

While tropical medical field research on malaria was limited to Germany until 1984, research into kidney and liver complications in schistosomiasis (schistosomiasis) was carried out in 20 countries from 1984 to 2000. Ehrich's Hanoverian working group, under the leadership of Ekkehard Döhring, demonstrated the superiority of ultrasound diagnostics and differentiated urine analysis to determine organ complications in the tropics . From then on, they became the gold standard alongside parasitological diagnostics . Furthermore, the positive effect of the anti-parasitic therapy on the reversibility of kidney and liver damage could be proven. The studies showed that, in contrast to malaria, schistosomiasis-induced acute lethality is low. If the praziquantel therapy is started in childhood, the long-term damage can also be greatly reduced. The studies supported numerous sponsors such as B. State Chancellery Lower Saxony and German Society for International Cooperation .

Not all research projects carried out on kidney involvement in tropical diseases were similarly successful. The model of the African trypanosomiasis- induced nephrotic syndrome in the rat, funded by the Collaborative Research Center of the DFG , did not become the standard model of idiopathic nephrosis in children, although it had many similarities, such as "minimal glomerular changes" and cyclosporine sensitivity. Unfortunately, the investigations for the characterization of podocytes were terminated before the triumphant advance of molecular genetic and molecular biological techniques in the 1990s and have not been resumed until today for the reasons listed below. Habu snake venom-induced glomerulopathy did not become the urgently needed rat model of the haemolytic uremic syndrome (HUS) in children. The complex reasons for the failure of the projects were, among other things, that animal models became obsolete due to increasing animal welfare. For the EHEC -diarrhea and Shiga toxin- induced HUS in children, there are no meaningful models available for research into targeted early therapies.

Ehrich summarized the clinical and experimental results on kidney involvement in all tropical diseases in three chapters of the German standard work on "Tropical Medicine in Clinic and Practice" by Thomas Löscher and Gerd-Dieter Burchard.

Ehrich also demonstrated the involvement of the kidneys in fever and non-tropical infectious diseases, malignant diseases, rheumatic diseases, heart diseases, lung and liver diseases, and physical activity, and published them in reviews. The results show that renal glomeruli and tubules dysfunction in a wide variety of diseases, most, but not all, of which are reversible.

Chemical laboratory research and diagnostics

Parallel to animal research, Ehrich has been developing increasingly complex laboratory methods for protein differentiation in serum and urine, as well as for kidney diagnostics, since 1974. These were e.g. For example, in the 1970s - together with Ulrich Wurster and Harald Foellmer - molecular weight-dependent electrophoresis techniques for proteinuria, in the 1980s individual biomarkers such as the C-reactive protein in serum, or tests for enzymuria. The diagnostic value was increased and standardized through innovative changes (chromatic silver coloring) and the establishment of complex expert systems (with Walter Guder and Walter Hofmann). At the turn of the millennium, the focus was on nephrological research on proteomics - together with Harald Mischak - and since 2013 metabolomics. These techniques are still in the development stage and, despite successful partial results, have not yet established themselves in the routine diagnosis of early stages of renal insufficiency .

Multicenter studies on nephrotic syndrome

Ehrich's clinical research from 1978 to 1990 focused on prospective, multicenter, randomized, controlled therapy studies for the treatment of steroid-sensitive nephrotic syndrome (SSNoS) under the direction of Johannes Brodehl. These studies on SSNoS achieved worldwide attention and their results are still considered therapy standards today.

A major therapeutic problem in childhood and adolescence until 1990 was the various therapy-resistant nephrotic syndromes (SRNoS). Such was the focal glomerulosclerosis (FSGS) for 10% of all terminal renal children the underlying cause and also came after a successful kidney transplant at 30 - the cases in the transplant 50% again.

Our own investigations produced five new findings: 1. The various glomerulonephritis with SRNoS were assigned more than 20 different congenital or acquired diseases with various disorders of the podocytes. 2. Not only circulating lymphocytes but also glomerular podocytes were identified as target cells for immunosuppressive therapies . 3. Induction therapy with a combination of cyclosporine A, intravenous methyl prednisolone pulson and oral prednisolone achieved a complete remission in 84% of the FSGS sufferers. 4. Maintenance therapy with cyclosporine A monotherapy was able to maintain a permanent remission in 60% of the cases with FSGS and in 38/40 treatment cases prevented a transition to chronic kidney failure after a mean observation period of 8 years. 5. Our own investigation came to the conclusion that old therapy recommendations under-treated the patients with immunological pathogenesis . In contrast, the patients with genetic defects were over-treated and exposed to drug toxicity without eliminating the proteinuria .

Epidemiological research and participation in the EDTA register in London

From 1986 to 1991 Ehrich was as a European of eight nephrologists in led by Felix Brunner Registry of European Dialysis and Transplant Association and European Renal Association operates (EDTA-ERA), in which the data of 300,000 adult and 10,000 pediatric patients with renal replacement therapy saved and analyzed annually. The scientific data were collected using “Center Questionnaires, Patient Questionnaires and Mini Questionnaires” and published in more than 50 publications during this period. In the pediatric field, there was close cooperation with Michel Broyer, Gianfranco Rizzoni, Anthony Wing and Chantal Loirat. This enabled numerous questions to be dealt with. The statistical analyzes did not reveal any fundamentally new diseases or relationships in children with kidney disease, but they were able to confirm or refute existing hypotheses and published individual findings through large numbers of patients. In the 1990s, for example, the analyzes of successful pregnancies in 1000 transplanted women showed that with good transplant function neither permanent loss of function of the transplant occurred nor an increased risk of malformations in the newborns. The reluctance of nephrologists and obstetricians towards planned pregnancies in kidney transplant women, which was still generally practiced in Germany at that time, was ended by the published findings. This enabled many transplanted women to receive positive counseling and the birth of a child and ultimately a high level of rehabilitation .

Transplant research

Numerous clinical papers dealt with kidney and liver transplantation topics in children. During his clinical work in Hanover and Berlin, Ehrich and numerous other colleagues looked after more than 1,600 transplant patients. With Guido Filler, the therapeutic drug monitoring for cyclosporine , tacrolimus and mycophenolate in particular was further expanded. With Lars Pape and Gisela Offner, numerous topics of the interactions between recipient and transplant were investigated, which ultimately led to the concepts of preferred living donation , preemptive transplantation, transplantation in infants or small children and organ donation “Young for Young”. As a result, the very young children in particular were referred for organ transplantation in transplant surgery with Rudolf Pichlmayr and Jürgen Klempnauer, as well as for pre- and post-care in the children's clinic at the MHH.

Discoveries, inventions and initial descriptions

Ehrich discovered a new disease in which not only the kidneys, but also the bones and growth, the brain vessels and the immune system are severely affected by a SMARCAL1 mutation. Parallel to Jürgen Spranger , who later published the changes in growth and the immune system, he was the first to describe the steroid-resistant nephrotic syndrome associated with the hereditary disease with focal segmental sclerosis and the successful kidney transplantation in this rare disease, as well as later other life-limiting complications in the form of transient ischemic attacks in the brain. Together with his colleague Thomas Lücke and his North American colleague Cornelius Boerkoel, the genetic and molecular biological principles and variabilities of the disease were later researched.

Together with Johannes Brodehl, Ehrich first described the involvement of the brain in adolescents with cystinosis. Together with Klaus-Peter Leipert, the complex eye damage caused by this hereditary disease was described for the first time. Johannes Brodehl's investigations were also continued in hypophosphatemic rickets and the long-term damage in adult patients was recorded for the first time.

Growth research

While working at the Charité at the Humboldt University in Berlin, Ehrich, together with Miroslav Zivicnjak and Doris Franke, laid the foundations for more than 20 years of research on growth disorders in children with kidney disease. The test results showed that body growth is a very good progress parameter for the severity of chronic diseases and for the quality of medical care. Within 20 years, the growth of the majority of kidney-deficient children was almost normalized through better drug therapy including growth hormone. The studies also showed the influence of prenatal factors ("fetal programming") on postnatal growth and the relationship between preterm birth and congenital and acquired kidney diseases.

Research on psychosocial aspects of chronic diseases

For more than 40 years, together with Georg Wolff and Lilly Damm, the psychosocial aspects of chronic kidney disease have been investigated and concepts for better doctor-patient communication, avoidance of non- adherence between patients and doctors, and improved rehabilitation have been developed and applied to numerous patients.

Social medical research on children's rights to health

From 2009 to 2011 Ehrich worked in a committee of the Council of Europe in Strasbourg to develop the Terms of References on children's rights with regard to their health. The implementation of the " child's rights to health from theory into practice" became one of his later work focuses. Numerous works and events on the subjects of "child friendly health care" and the participation of children in medicine were carried out at European level in order to close the existing knowledge and organizational gaps in various countries. Unfortunately, despite contact with German politicians, he has not yet succeeded in having the rights of the child to health included in the Basic Law of the Federal Republic of Germany .

At the European pediatrician congress EUROPAEDIATRICS 2015 in Florence, on his initiative, a high school graduate class took part in the symposium on children's rights in medicine for the first time.

Health services research

Ehrich has been involved in health services research (Child Health Care Service Systems in Europe) in the field of European paediatrics since 1998 . He established a network of presidents of national pediatric societies from 46 European countries and built up a steadily growing database, which for the first time enables a precise insight into the diversity of pediatric care systems in Europe . The findings are fed back by the national presidents and used by them in setting international standards in their own country.

In 2015 Ehrich was asked by the European Observatory to publish his findings on the future of children's clinics in Europe with an international team of authors. In this thesis it is proposed to replace the previous distinction between "primary, secondary and tertiary pediatric care" with a new classification that describes the respective tasks better and, above all, has new organizational concepts.

History of Pediatrics

During his active work in the clinic, Ehrich also devoted himself to questions about the history of paediatrics . In particular, together with international co-authors, he described the history of the European Society for Pediatric Nephrology (ESPN), the International Pediatric Nephrology Association (IPNA) and the European Pediatric Association (EPA) and Union of National European Pediatric Societies and Associations (UNEPSA).

Memberships in scientific associations

International level

Ehrich was a member of the Registry of European Dialysis and Transplant Association (EDTA) in London from 1988 to 1994, which records kidney replacement therapy in children in Europe. From 1994 to 1998 he was Secretary General of the Union of the National European Pediatric Societies and Associations (UNEPSA). Between 1994 and 1998 he was Departmental Coordinator of the Erasmus Program (European Credit Transfer System for the exchange of medical students (ECTS)) at the Humboldt University in Berlin. From 1997 to 2000 he was Assistant Secretary of the European Society of Pediatric Nephrology (ESPN) and from 1998 to 2000 President of the European Pediatric Association (EPA-UNEPSA), and from 2000 to 2003 Secretary General of ESPN. From 2009 to 2011 Ehrich was an expert in the Council of Europe for “Child-Friendly Health Care”; 2010 to 2016 treasurer of the European Pediatric Association (EPA-UNEPSA).

Academic tasks at national and university level

Member of the study commission in the international office of the Medical University of Hanover , representative for Great Britain, Czechoslovakia and France, as well as representative for the Erasmus program (departmental coordinator) of the Charité (Berlin).

Honors

Publications

Ehrich has published more than 250 scientific articles in English and 200 in German.

Web links

Individual evidence

  1. ^ H. Ebel, JHH Ehrich, NG DeSanto, U. Doerken: Plasma membranes of the kidney: III. Influence of diuretics on ATPase activity. In: Pflügers Arch. 335, 1972, p. 224.
  2. ↑ YES Bruijn, BS Oemar, JHH Ehrich, JM Foidart, Fleuren GJ: Anti Basement membrane glomerulopathy in experimental trypanosomiasis. In: Journal of Immunology. 139, 1987, pp. 2482-2488.
  3. ↑ JA Bruijn, BS Oemar, JHH Ehrich, GJ Fleuren: Immune complex formation in the kidney: recent observations in experimental trypanosomiasis. In: Ann. Soc. belge Med. trop. 68, 1988, pp. 11-14.
  4. ↑ B. Nonnast-Daniel, JHH Ehrich, GM Eisenbach, WG Daniel, KW Kuehn, PR Lichtlen, KM Koch: Is renal involvement a prognostic parameter in patients with infective endocarditis? In: European Heart Journal. 5 (Suppl.), 1984, p. 93.
  5. ^ R. Rossi, R. Kleta, JH Ehrich: Renal involvement in children with malignancies. In: Pediatr Nephrol. 13 (2), Feb 1999, pp. 153-162. Review.
  6. ↑ F. Bläker, JHH Ehrich: Systemic and rheumatic diseases with kidney involvement. In: U. Wahn, R. Seger, V. Wahn: Pediatric Allergology and Immunology. Gustav Fischer, Stuttgart 1994, pp. 545-550.
  7. ↑ G. Steinkamp, ​​M. Luetge, U. Wurster, JH Schulz-Baldes, HJ Groene, JHH Ehrich: Renal function in cystic fibrosis: lack of permanent nephrotoxicity after intravenous or aerosol tobramycin therapy. In: European Journal of Pediatrics. 145, 1986, p. 526.
  8. ↑ JHH Ehrich, F. Krull, C. Rosema, D. Byrd, J. Brodehl: Changes in the amino acid concentration in plasma and urine during physical exertion. In: German magazine for sports medicine. 35, 1984, p. 24.
  9. ^ JHH Ehrich, U. Wurster: Differentiation of proteinurias with electrophoresis. In: Pediatr Nephrol. 5, 1991, p. 376.
  10. ↑ JHH Ehrich, F. Krull, U. Peltner, A. Hussein, J. Stein: The importance of CRP for pediatric diagnostics. In: Mschr. Kinderheilk. 134, 1986, p. 840.
  11. ↑ A. Hussein, J. Stein, JHH Ehrich: C-reactive Protein in the Assessment of Disease Activity in Juvenile Rheumatoid Arthritis and Juvenile Spondyloarthritis. In: Scand. J. Rheumatology. 16, 1987, pp. 101-105.
  12. ↑ JHH Ehrich, U. Wurster, M. Luetge, I. Mertz, E. Doehring, BS Oemar: Enzymuria and kidney diseases in childhood. In: Mschr. Kinderheilk. 134, 1986, p. 832.
  13. ↑ JHH Ehrich, J. Strehlau: Idiopathic nephrotic syndrome. In: W. Proesmans: Therapeutic strategies children with renal disease. (= Baillère's Clinical Paediatrics. 5.4). Baillière-Tyndall, London 1997, ISBN 0-7020-2377-9 , pp. 539-575.
  14. ↑ JH Ehrich et al .: Steroid-resistant idiopathic childhood nephrosis: overdiagnosed and undertreated. In: Nephrol Dial Transplant. 22, 2007, pp. 2183-2193.
  15. ↑ E. Schönenberger, JH Ehrich, H. Haller, M. Schiffer: The podocyte as a direct target of immunosuppressive agents. In: Nephrol Dial Transplant. 26 (1), Jan 2011, pp. 18-24.
  16. Jump up ↑ M. Broyer, C. Chantler, R. Donckerwolcke, JHH Ehrich, G. Rizzoni, K. Schärer: The Pediatric Registry of the European Dialysis and Transplant Association: 20 years experience. In: Ped Nephrol. 7, 1993, pp. 758-768.
  17. ↑ L. Pape, JH Ehrich, M. Zivicnjak, G. Offner: Growth in children after kidney transplantation with living related donor graft or cadaveric graft. In: Lancet. 366, 2005, pp. 151-153.
  18. ↑ L. Pape, JH Ehrich, M. Zivicnjak, G. Offner: Living related kidney donation as an advantage for growth of children independent of glomerular filtration rate. In: Transplant Proc. 38 (3), Apr 2006, pp. 685-687.
  19. ↑ L. Pape, J. Hoppe, T. Becker, JH Ehrich, M. Neipp, T. Ahlenstiel, G. Offner: Superior long-term graft function and better growth of grafts in children receiving kidneys from pediatric compared with adult donors. In: Nephrol Dial Transplant. 21 (9), Sep 2006, pp. 2596-2600.
  20. ↑ JHH Ehrich, G. Offner, E. Schirg et al: Association of spondylo-epiphyseal dysplasia with nephrotic syndrome. In: Pediatr. Nephrol. 4, 1990, pp. 117-121.
  21. ↑ JHH Ehrich, W. Burchert, E. Schirg, F. Krull, G. Offner, PF Hoyer, J. Brodehl: Steroid resistant nephrotic syndrome associated with spondyloepiphyseal dysplasia, transient ischemic attacks and lymphopenia. In: Clin Nephrol. 43, 1995, pp. 89-95.
  22. ↑ G. Hillmann, H. Günay, S. Haker, JHH Ehrich, W. Geurtsen: Dental findings in hypophosphatemic vitamin D-resistant rickets. In: German Zahnärztl Zeitschr. 50, 1995, pp. 604-609.
  23. ↑ M. Zivicnjak, D. Franke, G. Filler, D. Haffner, K. Froede, R. Nissel, S. Haase, G. Offner, JH Ehrich, U. Querfeld: Growth impairment shows an age-dependent pattern in boys with chronic kidney disease. In: Pediatr Nephrol. 22 (3), Mar 2007, pp. 420-429.
  24. ^ D. Franke, S. Völker, S. Haase, L. Pavicic, U. Querfeld, JH Ehrich, M. Zivicnjak: Prematurity, small for gestational age and perinatal parameters in children with congenital, hereditary and acquired chronic kidney disease. In: Nephrol Dial Transplant. 25 (12), Dec 2010, pp. 3918-3924.
  25. ^ JHH Ehrich: Rehabilitation of adolescents and young adults with kidney replacement therapy in Europe. In: Social Pediatrics. 14, 1992, pp. 9-13.
  26. ↑ G. Wolff, JHH Ehrich .: Emotional relationships as a bridge between chronically and life-threatening sick children and their practitioners. In: Paths to People. 39, 1987, pp. 411-421.
  27. ↑ G. Rizzoni, JHH Ehrich, M. Broyer et al .: Rehabilitation of young adults during renal replacement therapy in Europe: 1. The presence of disabilities. Nephrol Dial Transplant. 7, 1992, pp. 573-578.
  28. ^ J. Goldhagen, R. Mercer, G. Robinson, E. Duran, E. Webb, J. Ehrich: Establishing a child rights, health equity, and social justice-based practice of pediatrics. In: J Pediatrics. 166, 2015, pp. 1098-1099.
  29. ^ S. Lenton, J. Ehrich: Approach to child-friendly health care — The Council of Europe. In: J Pediatr. 167, 2015, pp. 216-218.
  30. ↑ J. Ehrich, M. Pettoello-Mantovani, S. Lenton, L. Damm, J. Goldhagen: Participation of children and young people in their health care: understanding the potential and limitations. In: J Pediatr. 167, 2015, pp. 216-218.
  31. ↑ M. Katz, A. Rubino, J. Collier, J. Rosen, JH Ehrich: Demography of pediatric primary care in Europe: delivery of care and training. In: Pediatrics. 109 (5), May 2002, pp. 788-796.
  32. ↑ JH Ehrich, AA El Gendi, A. Drukker, J. Janda, C. Stefanidis, K. Verrier-Jones, J. Collier, M. Katz: Demography of pediatric renal care in Europe: organization and delivery. In: Nephrol Dial Transplant. 20, 2005, pp. 297-305.
  33. ^ I. Wolfe, M. Thompson, P. Gill, G. Tamburlini, M. Blair, A. van den Bruel, J. Ehrich, M. Pettoello-Mantovani, S. Janson, M. Karanikolos, M. McKee: Health services for children in Western Europe. In: Lancet. 381, 2013, pp. 1224-1234.
  34. ↑ J. Ehrich, A. Tenore, S. del Torso, M. Pettoello-Mantovani, DS Lenton, Z. Grossman: Diversity of pediatric workforce and education in 2012 in Europe: A need for unifying concepts or accepting enjoyable differences? In: J Pediatr. 167, 2015, pp. 471-476.
  35. ↑ M. Pettoello-Mantovani, J. Ehrich, A. Romondia, L. Nigri, L. Pettoello-Mantovani, I. Giardino: Diversity and differences of postgraduate training in general and subspecialty pediatrics in the European Union. In: J Pediatr. 165, 2014, pp. 424-426.
  36. ↑ a b J. Ehrich, D. Stengritt, D. Jaeger, L. Namazova-Baranova, M. Pettoello-Mantovani, S. Lenton The dilemma of international pediatric congresses in Europe: Starting the debate. In: J Pediatr. 166, 2015, pp. 504-506.
  37. ^ A. Gerber-Grote, S. Lenton, V. Amelung, M. Pettoello-Mantovani, J. Ehrich: Starting the Debate on the Role of Health Economics to Support Child Friendly Health Care in Europe. In: J Pediatr. 167, 2015, pp. 216-218.
  38. ↑ M. Salzer-Muhar, A. Pollak, C. Aufricht, J. Ehrich, S. Lenton: European challenges: cross-border care for children. In: J Pediatr. 161, 2012, pp. 574-576.
  39. ↑ J. Ehrich, R. Kerbl, M. Pettoello-Mantovani, S. Lenton: Opening the debate on pediatric subspecialties and specialist centers: opportunities for better care or risks of care fragmentation? In: J Pediatr. 167, 2015, pp. 1177–1178.
  40. ↑ K. Betke, JH Ehrich, J. Janda, M. Katz, A. Rubino: Thirty years of the Union of National European Pediatric Societies and Associations (UNEPSA). In: Eur J Pediatr. 166 (4), Apr 2007, pp. 349-357.
  41. ↑ G. Arneil, D. Boda, JH Ehrich, A. Fanconi, R. Habib, N. Hallman: The founding and early history of the European Society for Pediatric Nephrology (ESPN). In: Pediatr Nephrol. 22, Suppl 1, Apr 2007, pp. 1-15. Epub 2007 Feb 8.
  42. ↑ JH Ehrich, M. Pettoello-Mantovani, A. Rubino: Thirty-six years of the European Pediatric Association-Union of National European Pediatric Societies and Associations (EPA UNEPSA). In: J Pediatr. 161 (2), Aug 2012, pp. 374-375.
personal data
SURNAME Ehrich, Jochen HH
BRIEF DESCRIPTION German pediatrician and tropical medicine
DATE OF BIRTH January 5, 1946
PLACE OF BIRTH Braunschweig