Methyl chloroacetate
Structural formula | |||||||||||||||||||
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General | |||||||||||||||||||
Surname | Methyl chloroacetate | ||||||||||||||||||
other names |
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Molecular formula | C 3 H 5 ClO 2 | ||||||||||||||||||
Brief description |
Flammable, colorless liquid with a pungent odor |
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External identifiers / databases | |||||||||||||||||||
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properties | |||||||||||||||||||
Molar mass | 108.52 g mol −1 | ||||||||||||||||||
Physical state |
liquid |
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density |
1.23 g cm −3 |
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Melting point |
−33 - −32 ° C |
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boiling point |
131 ° C |
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Vapor pressure | |||||||||||||||||||
solubility |
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Refractive index |
1.4218 (20 ° C) |
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safety instructions | |||||||||||||||||||
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MAK |
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Toxicological data | |||||||||||||||||||
Thermodynamic properties | |||||||||||||||||||
ΔH f 0 |
−487.0 kJ / mol |
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As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C |
Methyl chloroacetate is a chemical compound from the group of chlorinated carboxylic acid esters .
Extraction and presentation
Methyl chloroacetate can be prepared from chloroacetic acid and methyl alcohol .
use
Methyl chloroacetate is used as an intermediate in the production of pharmaceuticals ( anti-inflammatory drugs , vitamin B2 , barbiturates ), pesticides ( dimethoates ), malonic acid ester derivatives, fragrances and heterocycles . It is also used for condensation with urea derivatives and as a solvent and as a flavor and fragrance.
safety instructions
The vapors of methyl chloroacetate can form an explosive mixture with air ( flash point 47 ° C, ignition temperature 465 ° C). The compound is also highly toxic.
Web links
- Entry on methyl chloroacetate in the Spectral Database for Organic Compounds (SDBS) of the National Institute of Advanced Industrial Science and Technology (AIST)
Individual evidence
- ↑ a b c d e f g h i j k l m Entry on methyl chloroacetate in the GESTIS substance database of the IFA , accessed on January 15, 2020(JavaScript required) .
- ↑ a b c d Toxicological assessment of methyl chloroacetate (PDF) at the professional association for raw materials and chemical industry (BG RCI), accessed on August 22, 2012.
- ↑ David R. Lide (Ed.): CRC Handbook of Chemistry and Physics . 90th edition. (Internet version: 2010), CRC Press / Taylor and Francis, Boca Raton, FL, Physical Constants of Organic Compounds, pp. 3-344.
- ↑ Entry on methyl chloroacetate in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on February 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
- ↑ Swiss Accident Insurance Fund (Suva): Limit values - current MAK and BAT values (search for 96-34-4 or methyl chloroacetate ), accessed on November 2, 2015.
- ↑ David R. Lide (Ed.): CRC Handbook of Chemistry and Physics . 90th edition. (Internet version: 2010), CRC Press / Taylor and Francis, Boca Raton, FL, Standard Thermodynamic Properties of Chemical Substances, pp. 5-23.