Xanthydrol

Structural formula
General
Surname	Xanthydrol
other names	9-hydroxyxanthene; 9-xanthenol; 9 H -xanthene-9-ol;
Molecular formula	C 13 H 10 O 2
Brief description	colorless to beige solid
External identifiers / databases
EC number	201-996-1
ECHA InfoCard	100.001.815
PubChem	72861
ChemSpider	65693
Wikidata	Q4021716
properties
Molar mass	198.22 g mol −1
Physical state	firmly
Melting point	127-128 ° C
solubility	soluble in methanol (50 g l −1 ); soluble in chloroform; practically insoluble in water;
safety instructions
GHS labeling of hazardous substances	no GHS pictograms
	no GHS pictograms
H and P phrases	H: no H-phrases
	P: no P-phrases
Toxicological data	500 mg kg −1 ( LD Lo , rat , oral )
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Xanthydrol is a heterocyclic chemical compound .

Extraction and presentation

Xanthydrol can be obtained by reducing xanthone with sodium amalgam in an alcoholic solution.

properties

Xanthydrol is a colorless to beige solid that is soluble in methanol . It can easily be oxidized to xanthone and forms salts with mineral acids.

use

Xanthydrol is used as a derivatizing reagent for the determination of acrylamide in surface and drinking water according to the GC-MS method and of urea (for example in blood) by HPLC with fluorescence detection. It is also used for the determination of phenol and as a reagent in the thin-layer chromatographic determination of indole and indole derivatives.

The xanthydrol reaction is the reaction of xanthydrol, acetic acid and hydrochloric acid with 2-deoxy sugar and 2,6-dideoxy sugar with the formation of color products.

Individual evidence

↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ data sheet Xanthydrol, 98% from Sigma-Aldrich , accessed on September 25, 2017 ( PDF ).
↑ ^a ^b ^c ^d ^e ^f Lexikon der Chemie: Xanthydrol - Lexikon der Chemie , accessed on September 25, 2017.
↑ RST BOWDEN: The Estimation of Blood Urea by the Xanthydrol Reaction. In: Journal of Small Animal Practice. 3, 1962, p. 217, doi : 10.1111 / j.1748-5827.1962.tb04191.x .
^ Gerhard Franz, Hildegard Koehler: Drugs and natural substances, basics and practice of chemical analysis . Springer-Verlag, 2013, ISBN 978-3-642-77376-1 , p. 105 ( limited preview in Google Book search).

[Sigma-1] ↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ data sheet Xanthydrol, 98% from Sigma-Aldrich , accessed on September 25, 2017 ( PDF ).

[Lexikon_der_Chemie-2] ↑ ^a ^b ^c ^d ^e ^f Lexikon der Chemie: Xanthydrol - Lexikon der Chemie , accessed on September 25, 2017.

[DOI10.1111/j.1748-5827.1962.tb04191.x-3] RST BOWDEN: The Estimation of Blood Urea by the Xanthydrol Reaction. In: Journal of Small Animal Practice. 3, 1962, p. 217, doi : 10.1111 / j.1748-5827.1962.tb04191.x .

[Gerhard_Franz,_Hildegard_Koehler-4] Gerhard Franz, Hildegard Koehler: Drugs and natural substances, basics and practice of chemical analysis . Springer-Verlag, 2013, ISBN 978-3-642-77376-1 , p. 105 ( limited preview in Google Book search).