Yoshio Masui

Yoshio Masui ( Japanese 増 井 禎 夫 , Masui Yoshio ; born January 1, 1931 in Kyoto ) is a Japanese / Canadian cell biologist and professor emeritus at the University of Toronto .

Life

Masui earned a bachelor's degree in 1953 and a master's degree in 1955 at the University of Kyoto , and in 1961 a Ph.D. with a thesis on the effects of lithium - ion on the embryogenesis of amphibians . At the Kōnan University in Kōbe he became an assistant in 1955, in 1958 he took over a teaching position as a lecturer ( kōshi ) and in 1965 a junior professorship ( jokyōju , English assistant professor ). During a research stay in 1966/1967 at Yale University in New Haven , Connecticut , he first worked in Clement L. Markert's group on isoenzymes of lactate dehydrogenase in penguin embryos, before starting new studies on the maturation of frog egg cells. To finish this work, he gave up his professorship in Kobe. In 1969 Masui received a professorship in zoology at the University of Toronto . In 1997 he retired.

Act

Masui discovered in his work on fertilized frog - and mouse - egg cells to maturation promoting factor (MPF) and Cytostatic factor (CSF). Both play a central role in initiating meiosis and mitosis . Their identification and characterization represent the starting point for research into the regulation of cell division .

Awards (selection)

• 1992 Gairdner Foundation International Award together with Leland H. Hartwell , Paul Nurse , Richard Peto , Bert Vogelstein and Robert Allan Weinberg
• 1998 Albert Lasker Award for Basic Medical Research together with Leland H. Hartwell and Paul Nurse
• 1998 membership in the Royal Society
• 2003 Officer of the Order of Canada
• 2003 membership in the Royal Society of Canada

literature

• Paul Nurse . Yoshio Masui and cell cycle control, past, present and future. Biology of the Cell (1998) 90, (447-452) doi: 10.1016 / S0248-4900 (99) 80002-1
• A tribute to Yoshio Masui. Biol Cell. 1998 Oct; 90 (6-7): 445-530. PMID 10084845

Web links

• Yoshio Masui at utoronto.ca (English); accessed on January 24, 2016
• JT Seimeishi Kenkyūkan ( JT Biohistory Research Hall ): 増 井 禎 夫 at brh.co.jp (Scientist Library Special ver., Japanese); Retrieved January 3, 2011. Published in the quarterly journal 生命 誌 ( Seimeishi , Eng. Biohistory ), No. 25, Vol. 7 (No. 3), 1999.

Individual evidence

1. ↑ Yoshio Masui at science.ca; Retrieved January 3, 2011
2. ↑ The discovery of MPF at bioscience.jbpub.com; Retrieved January 3, 2011
3. ↑ Yoshio Masui BSc, MSc, PhD at the Gairdner Foundation (gairdner.org); Retrieved December 9, 2012
4. ^ Albert Lasker Basic Medical Research Award 1998 Winners at laskerfoundation.org; Retrieved January 3, 2011
5. ↑ Fellows at royalsociety.org; Retrieved January 3, 2011
6. ↑ Yoshio Masui, OC, Ph.D., D.Sc., FRS at gg.ca; Retrieved January 3, 2011
7. ↑ Fellows at rsc.ca; accessed on January 24, 2016