Brenda Schulman

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Brenda A. Schulman (* 1967 in Tucson , Arizona ) is an American biochemist . She is best known for her work on the ubiquitin system.

Live and act

Schulman grew up in her native Tucson , Arizona . She received a BA in Biochemistry from Johns Hopkins University in 1989 and a Ph.D. in 1996 from Peter S. Kim at the Massachusetts Institute of Technology. in biology - interrupted by an internship with Christopher M. Dobson in Oxford . As a postdoctoral fellow, Schulman worked with Edward E. Harlow at Massachusetts General Hospital in Boston and with Nikola P. Pavletich at Memorial Sloan-Kettering Cancer Center in New York City .

From 2001 Brenda Schulman was a member of the scientific staff at St. Jude Children's Research Hospital in Memphis , Tennessee , most recently as co-director of the cancer genetics, biochemistry and cell biology program. Since 2004 she has been teaching at the University of Tennessee Health Science Center in Memphis. From 2005 to 2017 she also conducted research for the Howard Hughes Medical Institute (HHMI). Schulman has been a scientific member of the Max Planck Society and director at the Max Planck Institute for Biochemistry in Martinsried near Munich since 2017 . In addition, she has been an honorary professor at the Technical University of Munich since 2018 .

Schulman et al. Study the molecular mechanisms of the ubiquitin system. They are trying to clarify how ubiquitin and ubiquitin-like proteins (UBL) interact with their substrates , how they change the function of their target molecules and how disorders of these systems are associated with diseases. Methods from cell biology , biochemistry , structural biology , chemistry and genetics are used to identify regulatory mechanisms. Systems and volatile structures with multiple proteins ( molecular machines ) involved in ubiquitin reactions are visualized .

Schulman has been a member of the American Academy of Arts and Sciences since 2012, a member of the National Academy of Sciences since 2014 and a member of the European Molecular Biology Organization since 2018 . In 2019, Brenda A. Schulman was accepted as a member of the National Academy of Sciences Leopoldina in the Biochemistry and Biophysics Section .

For 2019 she was awarded a Gottfried Wilhelm Leibniz Prize . In 2019 she was also awarded the Ernst Jung Prize .

Web links

Individual evidence

  1. ^ Brenda A. Schulman, PhD. In: hhmi.org. Howard Hughes Medical Institute , accessed January 19, 2019 .
  2. ^ Brenda A. Schulman. In: mpg.de. Max Planck Society , accessed on January 19, 2019 .
  3. ↑ Book of Members 1780 – present, Chapter S. (PDF; 1.4 MB) In: American Academy of Arts and Sciences (amacad.org). Retrieved January 18, 2019 .
  4. ^ Brenda A. Schulman. In: nasonline.org. National Academy of Sciences , accessed January 19, 2019 .
  5. ^ Brenda A. Schulman. In: embo.org. European Molecular Biology Organization , accessed January 19, 2019 .
  6. ↑ Prof. Dr. Brenda Schulman - Gottfried Wilhelm Leibniz Prize Winner 2019. In: dfg.de. German Research Foundation , accessed January 19, 2019 .
personal data
SURNAME Schulman, Brenda
ALTERNATIVE NAMES Schulman, Brenda A.
BRIEF DESCRIPTION American biochemist
DATE OF BIRTH 1967
PLACE OF BIRTH Tucson , Arizona