Barry S. Coller
Barry Spencer Coller (* 1945 ) is an American physician and hemostaseologist (blood coagulation researcher) at Rockefeller University . He is best known for his contributions to understanding platelet aggregation and the receptors and ligands involved , including the fibrinogen receptors αIIbβ3 and GPIIb / IIIa and the Von Willebrand factor . Coller and co-workers were instrumental in the development of abciximab , an antibody fragment used to inhibit platelet aggregation.
Live and act
Coller earned a bachelor's degree from Columbia University in 1966 and an MD from New York University in 1970 with a medical degree. He began his residency in internal medicine at Bellevue Hospital in New York City , but moved to the National Institutes of Health in Bethesda , Maryland in 1972 to work on blood clotting. In 1976, Coller took over a first professorship (assistant professor) at the newly established department of blood coagulation at Stony Brook University . In 1982 he became an associate professor and in 1982 he was given a full professorship. Together with Arnold Levine , he developed various monoclonal antibodies against fibrinogen and Von Willebrand factor. Together with the company Centocor , the antibody 7E3 against fibrinogen receptors or its fragment abciximab was brought to market maturity. Together with Accumetrics , he developed an automated test to monitor platelet function in patients treated with abciximab, acetylsalicylic acid (ASA) and clopidogrel .
In 1994, Coller moved to the Mount Sinai School of Medicine as a professor of internal medicine , and in 2001 to head the Department of Blood and Vascular Biology at Rockefeller University . He did a lot of other work at both institutions on the interaction of 7E3 with various structures involved in blood clotting, including various integrins . Coller's other work deals with Glanzmann's thrombasthenia , a hereditary thrombocytopathy , and sickle cell anemia . Since 2012, Coller has also headed the Digestive System Diseases Research Division at Rockefeller University.
Awards (selection)
- 1982 Guggenheim scholarship
- 1997/1998 President of the American Society of Hematology
- 1998 National Research Achievement Award from the American Heart Association (with Oliver Smithies )
- 1998 Fellow of the American Association for the Advancement of Science
- 1999 member of the Institute of Medicine
- 2001 Warren Alpert Foundation Prize
- 2002 Honorary Doctorate from Mount Sinai School of Medicine
- 2003 member of the National Academy of Sciences
- 2003 Honorary Doctorate from the State University of New York at Stony Brook School of Medicine
- 2003 Dart / NYU Biotechnology Achievement Award
- 2005 Henry M. Stratton Medal
- 2005 member of the American Academy of Arts and Sciences
- 2005 Pasarow Award
- 2007 Honorary Doctorate from the North Shore-LIJ Graduate School of Molecular Medicine ( Hofstra University )
- 2012 George M. Kober Lectureship
- 2013 Honorary Doctorate from Baylor College of Medicine
- 2013 Karl Landsteiner Memorial Award
literature
- Christen Brownlee: Biography of Barry S. Coller . In: Proceedings of the National Academy of Sciences . tape 101 , no. 36 , September 7, 2004, p. 13111 , doi : 10.1073 / pnas.0405839101 (English).
Web links
- Barry S. Coller, MD and at Rockefeller University (rockefeller.edu)
Individual evidence
- ^ John Simon Guggenheim Foundation - Barry S. Coller. In: gf.org. Retrieved May 7, 2017 .
- ↑ Coller, Barry. In: aaas.org. February 24, 2017, accessed May 7, 2017 .
- ↑ Barry S. Coller. In: warrenalpert.org. Retrieved May 7, 2017 .
- ↑ Barry Coller. In: nasonline.org. Retrieved May 7, 2017 .
- ↑ https://www.rockefeller.edu/news/4831-cori-bargmann-honored-with-dartnyu-biotechnology-achievement-award
- ^ Henry M. Stratton Medal Recipients (Formerly Lecture). In: hematology.org. Retrieved May 7, 2017 .
- ↑ Book of Members 1780 – present (PDF, 1.3 MB) at the American Academy of Arts and Sciences (amacad.org); accessed on May 7, 2017.
- ↑ George M. Kober Medal and Lectureship. In: aap-online.org. Retrieved May 7, 2017 .
- ^ List of Past AABB Award Recipients. In: aabb.org. May 7, 2017, accessed May 7, 2017 .
| personal data | |
|---|---|
| SURNAME | Coller, Barry S. |
| ALTERNATIVE NAMES | Coller, Barry; Coller, Barry Spencer |
| BRIEF DESCRIPTION | American medical doctor and blood coagulation researcher |
| DATE OF BIRTH | 1945 |