David S. Hogness
David Swenson Hogness (born November 17, 1925 in Oakland , California , † December 24, 2019 in Stanford , California) was an American biochemist , geneticist and developmental biologist and professor , most recently retired , at Stanford University School of Medicine .
Life
Hogness' parents were the chemist Thorfin R. Hogness and his wife Phoebe S. Hogness. David Hogness earned a bachelor's degree in chemistry from the California Institute of Technology (Caltech) in 1949 and a Ph.D. in 1952. in biology and chemistry. As a postdoctoral fellow , he worked with a scholarship (Fellow) of the National Research Council at Jacques Monod at the Pasteur Institute in Paris and with a grant from the National Science Foundation at the New York University in New York City .
1955 took over Hogness first teaching positions (Instructor) in microbiology at the Washington University in St. Louis , Missouri , before 1957 there received a first professorship (Assistant Professor) . In 1959 he moved to Stanford University in Stanford , California as an assistant professor of biochemistry . In 1961 he became associate professor , in 1966 he was given a full professorship, and in 1989 he was also appointed to developmental biology . In 1999 he retired .
Hogness married Judith Gore in 1948 and the couple have two sons.
Act
Hogness contributed significantly to the understanding of the ontogeny of Drosophila melanogaster . He investigated the role of the hormone ecdysone in the development of the fruit fly. 1978 Hogness and staff found the TATA box (Goldberg-Hogness box) as a starting sequence for the transcription of genes in eukaryotes . Hogness' work contributed to the discovery that the genetic material of eukaryotes contains coding ( introns ) and non-coding ( exons ) segments and that the expression of numerous genes is regulated by so-called cis elements . Hogness helped merge genetics , molecular biology and developmental biology into the field of genomics .
Awards (selection)
- 1965 Newcomb Cleveland Prize
- 1968 Guggenheim Fellow
- 1976 member of the National Academy of Sciences
- 1976 member of the American Academy of Arts and Sciences
- 1977 Howard Taylor Ricketts Award
- 1979 Harvey Lecturer
- 1984 Genetics Society of America Medal
- 1992 Membership in the European Molecular Biology Organization (EMBO)
- 1995 Humboldt Research Prize
- 1997 March of Dimes Prize in Developmental Biology
- 2003 Thomas Hunt Morgan Medal
- 2007 International Prize for Biology
- 2013 Warren Alpert Foundation Prize
literature
- Michael W. Young: David Hogness (1925-2019). In: Current Biology. Volume 30, No. 5, PR194-R196, 2020, doi: 10.1016 / j.cub.2020.01.085 .
Web links
- David S. Hogness and curriculum vitae (PDF, 221 kB, as of 2000) at Stanford University (stanford.edu); Retrieved March 16, 2012
Individual evidence
- ↑ Krista Conger: Stanford biochemist David Hogness, a founder of genomics, dies at 94. Stanford Medicine, January 8, 2020, accessed January 14, 2020 .
- ^ John Simon Guggenheim Foundation - David S. Hogness. In: gf.org. Retrieved February 12, 2016 .
- ↑ Book of Members 1780 – present (PDF, 313 kB) of the American Academy of Arts and Sciences (amacad.org); Retrieved March 16, 2012
- ↑ a b Past GSA Award Recipients at the Genetics Society of America (genetics-gsa.org); Retrieved March 16, 2012
- ↑ March of Dimes Prize in Developmental Biology: Previous Recipients ( Memento of February 13, 2009 in the Internet Archive )
- ↑ Past Recipients: Dr. David Swenson Hogness at the Japan Society for the Promotion of Science (jsps.go.jp); Retrieved March 16, 2012
| personal data | |
|---|---|
| SURNAME | Hogness, David S. |
| ALTERNATIVE NAMES | Hogness, David; Hogness, David Swenson |
| BRIEF DESCRIPTION | American geneticist, biochemist, and developmental biologist |
| DATE OF BIRTH | November 17, 1925 |
| PLACE OF BIRTH | Oakland , California |
| DATE OF DEATH | December 24, 2019 |
| Place of death | Stanford , California |