Dimethylaminobenzaldehyde
Structural formula | |||||||||||||||||||
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General | |||||||||||||||||||
Surname | Dimethylaminobenzaldehyde | ||||||||||||||||||
other names |
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Molecular formula | C 9 H 11 NO | ||||||||||||||||||
Brief description |
light yellow to green solid |
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properties | |||||||||||||||||||
Molar mass | 149.19 g mol −1 | ||||||||||||||||||
Physical state |
firmly |
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Melting point |
72-75 ° C |
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boiling point |
176 ° C at 22.7 h Pa |
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solubility |
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safety instructions | |||||||||||||||||||
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Toxicological data | |||||||||||||||||||
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
Dimethylaminobenzaldehyde , or more precisely, 4- ( N , N -dimethylamino) benzaldehyde is a benzaldehyde - derivative , which in para position a N , N transmits -Dimethylaminorest.
use
A solution of 2% dimethylaminobenzaldehyde in 20% hydrochloric acid is called an Ehrlich reagent or Ehrlich-Pröscher reagent . It is used to detect primary amino groups , pyrrole and indole derivatives. The Ehrlich reagent was named after the discoverer Paul Ehrlich .
In medicine , the Ehrlich reagent is used to detect porphobilinogen and urobilinogen in urine ( Watson-Schwartz test and Hoesch test ).
In pharmacy , the Ehrlich reagent is used to detect pyrrole and indole derivatives (e.g. ergot alkaloids ) ( Van-Urk reaction ).
In microbiology , dimethylaminobenzaldehyde ( Kovacs reagent ) is used to detect indole ( indole test ). Since it is also suitable for the detection of LSD in this application , it has achieved a certain level of awareness in the drug scene .
Individual evidence
- ↑ a b c d data sheet dimethylaminobenzaldehyde from Acros, accessed on February 19, 2010.
- ↑ a b Entry on dimethylaminobenzaldehyde in the ChemIDplus database of the United States National Library of Medicine (NLM) .
- ↑ Data sheet 4- (Dimethylamino) benzaldehyde from Sigma-Aldrich , accessed on May 5, 2011 ( PDF ).
- ^ S. Ebel and HJ Roth (editors): Lexikon der Pharmazie , Georg Thieme Verlag, 1987, p. 213, ISBN 3-13-672201-9 .
literature
- Pröscher, F. (1900): On the knowledge of Ehrlich's dimethylamidobenzaldehyde reaction . In: Hoppe-Seyler's journal for physiological chemistry . Vol. 31, pp. 520-526.