Fenthion

Structural formula
General
Surname	Fenthion
other names	O , O -dimethyl- O- (4-methylthio- m -tolyl) phosphorothioate; Lebaycid; Mercaptophos; DMTP;
Molecular formula	C 10 H 15 O 3 PS 2
Brief description	colorless liquid
External identifiers / databases
EC number	200-231-9
ECHA InfoCard	100,000,211
PubChem	3346
Wikidata	Q418354
properties
Molar mass	278.3 g mol −1
Physical state	liquid
density	1.25 g cm −3 (20 ° C)
Melting point	6 ° C
boiling point	87 ° C (at 0.014 hPa)
solubility	practically insoluble in water (55 mg l −1 at 20 ° C)
Refractive index	1.5698 (20 ° C)
safety instructions
H and P phrases	H: 302-312-331-341-372-410
	P: 261-273-280-311-501
MAK	DFG : 0.2 mg m −3 ; Switzerland: 0.1 mg m −3 (measured as inhalable dust );
Toxicological data	140–615 mg kg −1 ( LD 50 , rat , oral )
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

Fenthion is a chemical compound from the group of organophosphates that is used as an insecticide .

history

Fenthion was developed by Bayer AG in 1958 and launched on the market in 1960.

properties

Chemically, fenthion belongs to the group of thiophosphoric acid esters and is a very difficult to ignite, colorless and odorless, and as a technical product brown, oily liquid with a slight smell of garlic. Fenthion is practically insoluble in water, but soluble in most organic solvents. Fenthion has a viscosity of 42.4 mPa · s at 20 ° C. It decomposes at temperatures above 135 ° C.

use

Fenthion is used as an insecticide ( acetylcholinesterase inhibitor) to combat mosquitoes , fleas and ticks and as an avicide and acaricide , for example in fish farming (poisoning of annoying fish or crabs). It is also effective against certain plants and is very poisonous to birds.

Fenthion is also important as an intermediate in the manufacture of other chemicals.

Admission

No plant protection products containing this active ingredient are permitted in the EU or Switzerland .

safety instructions

It is associated with the decline in numerous bird populations in the USA and, like all phosphoric acid esters, is also highly toxic to humans ( neurotoxin ). Fenthion is potentially mutagenic and can be absorbed through the skin. It degrades slowly in the environment.

Derived connections

Fenthion sulfoxide (CAS number: 3761-41-9): O , O -Dimethyl- O -4-methylsulfinyl- m -tolylthiophosphate
Fenthionsulfone (CAS number: 3761-42-0): O , O -Dimethyl- O -4-methylsulfonyl- m -tolylthiophosphate
Fenthionoxone (CAS number: 6552-12-1): O , O -Dimethyl- O -4-methylthio- m -tolylphosphate
Fenthionoxone sulfoxide (CAS number: 6552-13-2): O , O -Dimethyl- O -4-methylsulfinyl- m -tolylphosphate
Fenthionoxonsulfone (CAS number: 14086-35-2): O , O -Dimethyl- O -4-methylsulfonyl- m -tolylphosphate

Individual evidence

↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ Entry on fenthion in the GESTIS substance database of the IFA , accessed on February 1, 2016(JavaScript required) .
↑ ^a ^b ^c Australian Pesticides & Veterinary Medicines Authority: Fenthion Review Summary DECEMBER 2005 ( Memento of April 3, 2014 in the Internet Archive )
↑ Entry on Fenthion in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on February 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
↑ Swiss Accident Insurance Fund (Suva): Limit values - current MAK and BAT values (search for 55-38-9 or Fenthion ), accessed on November 2, 2015.
↑ WHO / FAO Data Sheet on Pesticides (PDS) for Fenthion ( Memento of October 13, 2014 in the Internet Archive )
↑ General Directorate Health and Food Safety of the European Commission: Entry on fenthion in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on March 26, 2016.
↑ Eur-Lex: Commission decision of February 11, 2004 on the non-inclusion of fenthion in Annex I of Council Directive 91/414 / EEC and the revocation of the authorizations for plant protection products containing this active substance .

Web links

Bayer: Fenthion ( Memento from August 19, 2012 in the Internet Archive )
Entry on Fenthion at Vetpharm

[GESTIS-1] ↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ Entry on fenthion in the GESTIS substance database of the IFA , accessed on February 1, 2016(JavaScript required) .

[AP-2] Australian Pesticides & Veterinary Medicines Authority: Fenthion Review Summary DECEMBER 2005 ( Memento of April 3, 2014 in the Internet Archive )

[CLP_100.000.211-3] Entry on Fenthion in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on February 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .

[4] Swiss Accident Insurance Fund (Suva): Limit values - current MAK and BAT values (search for 55-38-9 or Fenthion ), accessed on November 2, 2015.

[5] WHO / FAO Data Sheet on Pesticides (PDS) for Fenthion ( Memento of October 13, 2014 in the Internet Archive )

[6] General Directorate Health and Food Safety of the European Commission: Entry on fenthion in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on March 26, 2016.

[7] Eur-Lex: Commission decision of February 11, 2004 on the non-inclusion of fenthion in Annex I of Council Directive 91/414 / EEC and the revocation of the authorizations for plant protection products containing this active substance .