H. Ronald Kaback

Howard Ronald Kaback (born June 5, 1936 in Philadelphia , Pennsylvania , † December 20, 2019 ) was an American biochemist at the University of California, Los Angeles .

Life

At Haverford College , where he obtained a bachelor's degree in 1958 , Kaback first came into contact with molecular biology . He earned an MD from Albert Einstein College of Medicine in New York City in 1962 and later worked as an assistant doctor in pediatrics at the Bronx Municipal Hospital Center and as a postdoctoral fellow in physiology at Albert Einstein College of Medicine . In 1964, Kaback became Commissioned Officer in the United States Public Health Service (USPHS) in the Department of Biochemistry at the National Heart Institute (now the National Heart, Lung, and Blood Institute ), a facility of the National Institutes of Health based in Bethesda , Maryland . In 1970 he moved to the Roche Institute of Molecular Biology , in Nutley , New Jersey , where he was most recently head of the Department of Biochemistry . At the same time, he taught at Columbia University in New York City and the New Jersey Medical School . In 1989, Kaback went to the University of California, Los Angeles (UCLA) as a professor of physiology, microbiology and molecular genetics . Until 2004 he also conducted research for the Howard Hughes Medical Institute (HHMI)

Act

Kaback developed methods to isolate cell membranes from bacteria , which can be used to investigate general transport mechanisms and related phenomena on biomembranes . He was able to gain fundamental insights into the molecular mechanisms of sugar transport and what influence concentration gradients of ions play in this (see Major Facilitator Superfamily ).

Kaback focused in particular on energy converting (energy-transducing) transport proteins , which on membrane transport are involved, including the lacY gene product, which in E. coli glucose (mediated -transport permease ).

Awards (selection)

• 1974 Rosenstiel Award
• 1986 member of the American Academy of Arts and Sciences
• 1987 member of the National Academy of Sciences

Web links

• Howard Kaback at the University of California, Los Angeles (ucla.edu)
• Kaback Lab and HR Kaback at the University of California, Los Angeles (IP)
• Ronald Kaback, MD at the David Geffen School of Medicine of the University of California, Los Angeles (ucla.edu)
• Scientist studies 'third amino acid from left' at the University of California, Los Angeles (ucla.edu)

Individual evidence

1. ↑ ^{a b c} H. Ronald Kaback. In: nasonline.org. National Academy of Sciences , accessed December 29, 2019 . 
2. ↑ Kaback, Howard Ronald. In: legacy.com. December 26, 2019, accessed December 28, 2019 . 
3. ^ H. Ronald Kaback, MD and Research Abstract at the Howard Hughes Medical Institute (hhmi.org); Retrieved June 2, 2012
4. ^ Past Winners - Rosenstiel Award - Rosenstiel Basic Medical Sciences Research Center - Brandeis University. In: brandeis.edu. Retrieved January 23, 2016 . 
5. ↑ List of Members 1780 – present (PDF, 207 kB) at the American Academy of Arts and Sciences (amacad.org); Retrieved May 29, 2012