Hans Georg Fassbender

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Hans Georg Fassbender

Hans Georg Fassbender (born January 29, 1920 in Koblenz ; † May 28, 2015 ) was a German pathologist, professor of general pathology and pathological anatomy at the University of Mainz, and founder and director of the Center for Rheumatic Pathology .

Life

Hans Georg Fassbender began his medical studies in 1939, which he completed with the state examination after his time in the Navy from 1940 to 1945 . In 1946 and 1947 he worked as an assistant at the Pathological Institutes in Braunschweig and Mainz . In 1951 he became senior physician and private lecturer with a habilitation in general pathology and pathological anatomy at the University of Mainz . After six years as head of the Pathological Institute in Mainz, he accepted a one-year call to the Pathological Institute of the University of Zurich in 1958 , where he acted as the first prosector . In 1960 he returned to the University of Mainz as a permanent professor. In 1964 Fassbender joined the German Armed Forces , within which he founded a central institute for general and experimental pathology on behalf of the Federal Ministry of Defense as a chief pathologist and later a fleet doctor . He left the Bundeswehr in 1977. In 1974 he founded the Center for Rheumatic Pathology - since then he has been director of the institute.

Fassbender is the author of 290 publications and 790 lectures (Invited Lectures) and has contributed to numerous German, English and Japanese manuals and textbooks, especially in the field of rheumatology and endocrinology .

Services

  • Uncovering the importance of reactive synovitis in osteoarthritis , which formed the basis for the use of anti-inflammatory drugs in therapy
  • Evidence of the oncological character of joint destruction in rheumatoid arthritis , which destroys cartilage and bones in short repeated attacks
  • Uncovering ultrastructural changes in polymyalgia rheumatica
  • Discovery of a non-inflammatory mechanism of the bone and joint processes in arthritis psoriatica and other diseases from the group of seronegative spondarthritis
  • Evidence of specific vascular changes in the synovial tissue in psoriatic arthritis and ankylosing spondylitis , which means that ankylosing spondylitis disease can only be predicted later in adolescence and thus preventive measures can be taken
  • Detection of a clinically latent form of bacterial arthritis (KLBA)
  • Detection of self-limiting bacterial superinfections in chronic joint diseases , which are very common (37%), but mostly remain clinically undetected
  • Structural analysis of chronically recurrent joint effusions
  • Uncovering the pathomechanisms of primarily necrotizing processes and their significance for the malignant course of rheumatoid arthritis

Memberships, functions

  • Adjunct Professor of Medicine, University of Alabama , Birmingham , Alabama
  • Visiting Professor of Pathology, Rush Medical College, Chicago , Illinois
  • Visiting Professor of Rheumatology and Immunology, Duke University Medical Center, Durham , North Carolina
  • Professor Honorário de Universidade Federal de Pernambuco, Recife , Brazil
  • Visiting Professor of Pathology at the University of Zagreb , Croatia
  • Director, Section Pathology, WHO Center, Birmingham, Alabama
  • Honorary member of 13 international academies and scientific societies, including the German Society for Rheumatology
  • President, Vice-President and Coordinator of the Scientific Program at the European Congress of Rheumatology (1971–79)
  • Senior reviewer on behalf of the British Medical Council for research proposals and results from five working groups at Strangeways Laboratories, Cambridge
  • Founder and head of the Rhineland-Palatinate regional association of the German Rheumatism League in 1976, then honorary president
  • Founder and since then honorary chairman of the information group for parents of children with rheumatism (since 1980)

Selected honors

  • Carol Nachman Prize 1976
  • Albertus Magnus Medal for Services to Art and Science 1980
  • Eular Meritorious Service Award Berlin
  • Medal of Honor from the Armed Forces Institute of Pathology (AFIP), Washington
  • Federal Cross of Merit 1st class for services to the international reputation of German science 1993

Standard work

  • Pathology and Pathobiology of Rheumatic Diseases . 2nd edition, Springer, Heidelberg 2002, ISBN 3-540-62942-4 (first edition in English, German and Japanese)

Individual evidence

  1. HG Fassbender: The importance of inflammatory processes in osteoarthritis . In: Z. Rheumatol. Volume 42, 1983, pp. 145-151.
  2. ^ HG Fassbender: Rheumatoid Arthritis . In: Spezial pathologische Anatomie Vol. 18 Pathology of the joint and soft tissue tumors , ed. W. Doerr, G. Seifert. Springer, Berlin and Heidelberg 1984, pp. 191-229.
  3. HG Fassbender: Normal and pathological synovial tissue with emphasis on rheumatoid arthritis In: Rheumatology and Immunology , 2nd Ed. (ed. AS Cohen and JC Bennett), Grune & Stratton, Orlando-New York 1986, pp. 36-42. ISBN 0-8089-1809-5
  4. HG Fassbender: The psoriatic bone process . In: Psoriasis and joint diseases (eds. U. Wollina, G. Mein, B. Knopf), Gustav-Fischer-Verlag, Jena and Stuttgart 1996, pp. 65–75.
  5. HG Fassbender and R. Fassbender: Synovial characteristics of seronegative spondarthritides . In: Clin. Investig. Volume 70, 1992, p. 706.
  6. ^ HG Fassbender: Pathology and Pathobiology of Rheumatic Diseases . Springer, Heidelberg 2002.
  7. ^ HG Fassbender: Inflammatory Reactions in Arthritis . In: Handbook of Immunopharmacology: Immunopharmacology of Joints and Connective Tissue (eds .: ME Davies, JT Dingle), Academic Pres, London [et al.] 1994, pp. 165-198. ISBN 0-12-206345-7

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