Peter M. Schlag

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Peter Michael Schlag (born April 22, 1948 in Passau ) is a German oncological surgeon .

Life

Schlag graduated from high school in Bad Tölz in 1967 . He then studied at the University of Dusseldorf medicine, where in 1973 he earned the state exam in 1974 when Wolfgang Staib with work studies on the relationship between enzyme leakage and electrolyte imbalance in the liver doctorate was. He completed his specialist training in surgery until 1980 at Ulm University Hospital , interrupted by a research stay with Sydney Salmon at the University of Arizona in Tucson , Arizona . Further research stations were with Bill McGuire at the University of Texas at San Antonio and George A. Higgins at Veterans Administration Surgical Adjuvant Cancer in Washington, DC in 1981 habilitated to blow with the work Clinical and animal studies to the pathogenesis of carcinoma in the operated stomach and was in the same year under Christian Herfarth senior physician at the Ulm University Hospital.

In 1982 Schlag received a professorship for oncological surgery at Heidelberg University Hospital . With a grant from the German Society for Surgery , he visited several cancer centers in the United States in 1987 (including the Memorial Sloan Kettering Cancer Center , the National Cancer Institute , the University of Texas MD Anderson Cancer Center and the Mayo Clinic ). In 1987/88 he was visiting doctor at the Thoraxklinik Heidelberg , in 1988 and 1990 visiting professor at the Roswell Park Memorial Institute in Buffalo , New York . In 1992 Schlag became Professor of Surgery and Surgical Oncology at the Charité Berlin, which at the time belonged to the Free University of Berlin , and from 1999 to the Humboldt University in Berlin . Also in 1992 he became director of the Clinic for Surgery and Surgical Oncology at the Robert-Rössle-Klinik (a successor to the Central Institute for Cancer Research ) at the Max Delbrück Center , which was spun off into the Helios Clinic Berlin-Buch in 2001 . In 2008 he became the founding director of the Charité Comprehensive Cancer Center . In 2013 Schlag retired from the Charité Universitätsmedizin Berlin .

Peter M. Schlag has been married since 1971 and has two children.

Act

Peter M. Schlag made an outstanding contribution to the further development of diagnostics and therapy for solid tumors on the basis of molecular biological knowledge and the integration of telematics-supported and computer-supported surgical techniques.

Schlag was one of the first visceral surgeons in the world to develop and use 3D visualization of tumors on the basis of imaging diagnostics for surgical planning and instrument navigation for the resection of liver metastases . He founded the section “Computer and Telematics Assisted Surgery” in the German Society for Surgery and was the editor of the first German-language textbook on it.

Schlag has clinically developed the method of sentinel lymph node diagnostics for tumors in the gastrointestinal tract . To this end, he investigated various marking methods for intraoperative tumor visualization. He is considered a pioneer of several multimodal treatment methods, including tumor cell vaccination (see cancer vaccine ), therapeutic hyperthermia , isolated limb perfusion (ILP) and hyperthermic intraperitoneal chemotherapy (HIPEC), which he tested in clinical studies .

Schlag's working group identified the MACC-1 gene , which promotes tumor growth and metastasis in colon cancer and whose activity is prognostically important. Based on this, a blood test was also developed. Schlag's later work dealt with Whole Tumor Genome Sequencing (WTGS) and attempts to establish other meaningful biomarkers for cancer.

According to the Scopus database , Schlag has an h-index of 75 (as of January 2020). He was (co-) editor of several scientific journals , including Der Onkologe , European Journal of Cancer , The Oncologist , Oncology and Recent Results in Cancer Research .

Awards (selection)

Web links

  • CV (PDF; 164 kB) at the Leopoldina
  • CV at ACO-ASSO

Individual evidence

  1. Schlag, Peter Michael. In: scopus.com. Scopus , accessed January 19, 2020 .
  2. German Cancer Prize. In: krebsgesellschaft.de. German Cancer Society, accessed on January 19, 2020 .
  3. Member entry of Peter M. Schlag at the German Academy of Natural Scientists Leopoldina
  4. Invitation to the presentation of the Johann Georg Zimmermann Prize 2019/2020. In: mhh-plus.de. Promotion Foundation MHH plus, December 11, 2019, accessed on January 19, 2020 .