Suzanne Cory

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Suzanne Cory (born March 14, 1942 in Melbourne ) is an Australian molecular biologist and immunogeneticist . She was President of the Australian Academy of Science from 2010 to 2014 .

Life

Cory earned a bachelor's degree in 1964 and a master's degree from the University of Melbourne in 1965 . Your Ph.D. obtained it from the University of Cambridge in England. She worked as a postdoctoral fellow at the University of Geneva before joining the Walter and Eliza Hall Institute of Medical Research (WEHI) in Parkville , Victoria as a research assistant in 1972 . Here she went through numerous career stages until she became director in 1996. From 1993 to 1996 she was a research professor at the University of Melbourne, and in 1996 she was given a full professorship. In 2009 she was succeeded by Doug Hilton as Director of WEHI.

Cory published numerous papers together with her husband Jerry Adams (* 1940), who is also a researcher at WEHI. The couple have two daughters.

Act

Cory's research was instrumental in understanding cancer immunology and carcinogenesis . In her doctoral thesis on methionine transfer RNA , she applied the sequencing method newly developed by Fred Sanger ( DNA sequencing # Dideoxy method according to Sanger ). As a postdoc , she worked on the sequence analysis of the R17 phage RNA as a model mRNA . Together with Adams she discovered the 5'-cap structure of the mRNA and introduced the technique of cloning in Australia. They carried to answer the question as to the mechanisms that allow the immune system allow antibodies against wide variety of antigens to form: by V (D) J recombination , the genes encoding the antibody in a vast variety of combinations composed become. From 1981, Adams and Cory turned to the genetic causes of cancer . They were able to show that chromosome damage can activate genes that promote cancer ( oncogenes ). They identified the mutation that activates the myc oncogene and causes Burkitt's lymphoma . Together with Alan Harris, they developed transgenic strains of laboratory mice that are susceptible to lymphomas and thus serve as model organisms for researching the molecular mechanisms of lymphomas. Later work dealt with the Bcl-2 gene, which is responsible for the development of follicular lymphoma and, as the first known oncogene, does not promote cell proliferation , but regulates apoptosis (programmed cell death). Understanding the control of apoptosis and its importance for cancer and other diseases should pave the way for new therapeutic methods.

Awards (selection)

Since 2011 there is the Suzanne Cory High School in Victoria , Australia .

Publications (selection)

Web links

Individual evidence

  1. ^ The president - Australian Academy of Science. In: science.org.au. Retrieved January 1, 2017 .
  2. ^ Professor Suzanne Cory at the Australian Academy of Science (science.org.au); accessed on May 16, 2019.
  3. ^ Charles S. Mott Prize (1990–2002) ( Memento of March 14, 2007 in the Internet Archive )
  4. ↑ 1998 Australia Prize ( Memento from March 5, 2016 in the Internet Archive )
  5. ↑ Book of Members 1780 – present, Chapter C. (PDF; 1.3 MB) In: American Academy of Arts and Sciences (amacad.org). Retrieved May 16, 2019 .
  6. ^ L'Oréal UNESCO Prize: "For Women in Science" at unesco.de; Retrieved January 12, 2012
  7. ^ Royal Medal at the Royal Society (royalsociety.org); Retrieved January 12, 2013
  8. ↑ Suzanne Cory - List of the membres de l'Académie des sciences. In: academie-sciences.fr. Retrieved February 21, 2016 (French).
  9. ^ Suzanne Cory at the Pontifical Academy of Sciences (casinapioiv.va); Retrieved January 12, 2013
  10. ^ Professor Suzanne Cory-AC, PhD, PresAA, FRS - About Us. In: suzannecoryhs.vic.edu.au. Retrieved February 21, 2016 .
personal data
SURNAME Cory, Suzanne
BRIEF DESCRIPTION Australian molecular biologist and immunogeneticist
DATE OF BIRTH March 14, 1942
PLACE OF BIRTH Melbourne