Tetrahydrofurfuryl alcohol

Structural formula
General
Surname	Tetrahydrofurfuryl alcohol
other names	2-hydroxymethyl tetrahydrofuran; 2- (tetrahydrofuryl) methanol; Tetrahydrofurfural alcohol; Tetrahydro-2-furancarbinol; THFA;
Molecular formula	C 5 H 10 O 2
Brief description	colorless, oily liquid with a pleasant odor
External identifiers / databases
EC number	202-625-6
ECHA InfoCard	100.002.387
PubChem	7360
ChemSpider	7082
Wikidata	Q2406741
properties
Molar mass	102.13 g mol −1
Physical state	liquid
density	1.06 g cm −3
Melting point	<−80 ° C
boiling point	178 ° C
Vapor pressure	1 h Pa (25 ° C)
solubility	miscible with water, ethanol , diethyl ether , acetone , chloroform and benzene
Refractive index	1.451-1.453
safety instructions
H and P phrases	H: 319-360Df
	P: 201-305 + 351 + 338-308 + 313
Toxicological data	1.6–3.2 g kg −1 ( LD 50 , rat , oral )
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

Tetrahydrofurfuryl alcohol is a chemical compound from the group of oxygen-containing heterocycles and hydroxyethers .

Extraction and presentation

Tetrahydrofurfuryl alcohol is obtained by catalytic hydrogenation of furfuryl alcohol and subsequent distillation .

It is one of the chemical substances that are produced in large quantities (" High Production Volume Chemical ", HPVC) and for which the Organization for Economic Cooperation and Development (OECD) collects data on possible hazards (" Screening Information Dataset ", SIDS ) was made.

properties

Tetrahydrofurfuryl alcohol is a colorless, hygroscopic , oily and hardly inflammable liquid with a pleasant odor. Tetrahydrofurfuryl alcohol has a viscosity of 6.24 mPas. Tetrahydrofurfuryl alcohol vapors are 3.5 times heavier than air.

use

Tetrahydrofurfuryl alcohol is used as a solvent , chiral auxiliary and as a test substance to develop methods for the separation of enantiomers . It is also contained in detergents and polymerization initiators or catalysts and is used in the manufacture of insecticides and pharmaceuticals.

safety instructions

The vapors of tetrahydrofurfuryl alcohol and air form an explosive mixture (flash point 74 ° C, ignition temperature 280 ° C). It reacts violently with strong oxidizing agents. The use of the substance in toys and the like is not permitted in Germany.

Individual evidence

↑ ^a ^b ^c ^d ^e ^f ^g ^h Entry on tetrahydrofurfuryl alcohol in the GESTIS substance database of the IFA , accessed on February 1, 2016(JavaScript required) .
↑ ^a ^b ^c OECD: IUCLID Datasheet
↑ Entry on tetrahydrofurfuryl alcohol at ChemBlink , accessed on February 25, 2011.
↑ Entry on Tetrahydrofurfuryl alcohol in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on February 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
↑ ^a ^b ^c OECD : Screening Information Dataset (SIDS) Initial Assessment Report (SIAR) for 2-furanmethanol, tetrahydro- , accessed on November 4, 2014.

[GESTIS-1] ↑ ^a ^b ^c ^d ^e ^f ^g ^h Entry on tetrahydrofurfuryl alcohol in the GESTIS substance database of the IFA , accessed on February 1, 2016(JavaScript required) .

[iuclid-2] OECD: IUCLID Datasheet

[3] Entry on tetrahydrofurfuryl alcohol at ChemBlink , accessed on February 25, 2011.

[CLP_100.002.387-4] Entry on Tetrahydrofurfuryl alcohol in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on February 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .

[SIDS-5] OECD : Screening Information Dataset (SIDS) Initial Assessment Report (SIAR) for 2-furanmethanol, tetrahydro- , accessed on November 4, 2014.