from Wikipedia, the free encyclopedia
Structural formula
Structural formula of tetrahydrothiophene
Surname Tetrahydrothiophene
other names
  • THT
  • Tetramethylene sulfide
  • Thiolane
Molecular formula C 4 H 8 S
Brief description

colorless liquid with an unpleasant odor

External identifiers / databases
CAS number 110-01-0
EC number 203-728-9
ECHA InfoCard 100.003.391
PubChem 1127
ChemSpider 1095
Wikidata Q412118
Molar mass 88.17 g mol −1
Physical state



1.00 g cm −3

Melting point

−96 ° C

boiling point

121 ° C

Vapor pressure

19 h Pa (20 ° C)

Refractive index


safety instructions
GHS hazard labeling from  Regulation (EC) No. 1272/2008 (CLP) , expanded if necessary
02 - Highly / extremely flammable 07 - Warning


H and P phrases H: 225-302 + 312 + 332-315-319-412
P: 210-273-302 + 352-305 + 351 + 338-403 + 235

DFG / Switzerland: 50 ml m −3 or 180 mg m −3

Toxicological data

1750 mg kg −1 ( LD 50ratoral )

As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

Tetrahydrothiophene (THT) is a saturated sulfur heterocycle .

Extraction and presentation

Tetrahydrothiophene can be obtained from tetrahydrofuran and hydrogen sulfide .


Tetrahydrothiophene is a colorless liquid and can already be smelled at a concentration of 0.001  ppm (reminiscent of rotten eggs, garlic, coal gas).


THT is used as an odorant (odor = odor; odorant) in natural gas . Since natural gas is almost odorless, the regional gas suppliers vaccinate natural gas in their gas pressure regulating systems / gas pressure regulating and measuring systems with a concentration of around 20 mg · m −3 in order to give early warning of any leaky pipe installation. In addition to its unmistakable smell, THT is chemically stable. THT leaked from leaky underground lines is poorly absorbed by the ground. As a result of pipeline defects, the smell can also come to the surface. When burned with natural gas, however, it burns odorless.

safety instructions

As a released liquid, THT evaporates very quickly and can form highly flammable vapors when mixed with air, because the lower explosion limit is 1.1% by volume, the ignition temperature is 200 ° C, the flash point is 13 ° C. THT is comparable to gasoline in terms of fire and explosion risk. THT vapors are heavier than air and are irritating to the eyes, respiratory tract and skin. In liquid form, it is also absorbed through the skin. The LD 50 value (oral, rat) is 1750 mg kg −1 .

Individual evidence

  1. a b c Entry on tetrahydrothiophene. In: Römpp Online . Georg Thieme Verlag, accessed on September 29, 2014.
  2. a b c d e f g h i j k l m Entry on tetrahydrothiophene in the GESTIS substance database of the IFA , accessed on February 1, 2016(JavaScript required) .
  3. Entry on Tetrahydrothiophene in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on February 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
  4. Swiss Accident Insurance Fund (Suva): Limit values ​​- current MAK and BAT values , accessed on November 2, 2015.
  5. Tetrahydrothiophene data sheet from Sigma-Aldrich , accessed on January 17, 2011 ( PDF ).Template: Sigma-Aldrich / name not given
  6. IA Sharipova, Kh. M. Nasyrov, A. Kh. Sharipov, and MF Mazitov, "Synthesis of Tetrahydrothiophene from Tetrahydrofuran and Hydrogen Sulfide", Russian J. Org. Chem. 36 (1), 105 (2000).