Thorsten Bach

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Thorsten Bach (2018)

Thorsten Bach (born April 15, 1965 in Ludwigshafen am Rhein ) is a German chemist and professor of organic chemistry at the Technical University of Munich .

Life

Bach studied chemistry at the Ruprecht-Karls-Universität in Heidelberg and graduated in 1988 with a diploma thesis in the work of George A. Olah at the University of Southern California in Los Angeles . He then moved to the Philipps University in Marburg , where he received his doctorate in 1991 under Manfred T. Reetz . After a post-doctoral stay with David A. Evans at Harvard University in Cambridge (Massachusetts) , he began his independent research career in 1992 with Dieter Hoppe at the Westphalian Wilhelms University in Münster . In 1997, Bach was appointed university professor at the Philipps University in Marburg, followed by a call to the Technical University of Munich in 2000 .

plant

Thorsten Bach has been researching stereoselective photochemical reactions for many years . During his habilitation, the focus was on the diastereoselective synthesis of oxetanes by the Paternò-Büchi reaction . From 2000 onwards, enantioselective photochemical reactions were in the foreground - initially with a stoichiometrically added chiral template, since 2005 with the use of various chiral photocatalysts and chiral Lewis acids . Further research focuses on transition metal catalysis and the use of free carbenium ions in diastereoselective Friedel-Crafts alkylations . Results from all three main research areas found their way into the total synthesis of a number of natural products.

Awards and memberships

Web links

Individual evidence

  1. ↑ biographical data, publications and Academic pedigree of Thorsten Bach at academictree.org, accessed on January 6, 2018th
  2. ↑ T. Bach, K. Jödicke, K. Kather, R. Fröhlich: 1,3-Allylic Strain as a Control Element in the Paternò-Büchi Reaction of Chiral Silyl Enol Ethers: Synthesis of Diastereomerically Pure Oxetanes Containing Four Contiguous Stereogenic Centers , J. Am. Chem. Soc. 1997 , 119 , 2437-2445, doi: 10.1021 / ja963827v .
  3. ↑ T. Bach, H. Bergmann, K. Harms: Enantioselective Intramolecular [2 + 2] -Photocycloaddition Reactions in Solution , Angew. Chem. Int. Ed. 2000 , 39 , 2302-2304, doi : 10.1002 / 1521-3773 (20000703) 39:13 <2302 :: AID-ANIE2302> 3.0.CO; 2-6 , Angew. Chem. 2000 , 112 , 2391-2393, doi : 10.1002 / 1521-3757 (20000703) 112: 13 <2391 :: AID-ANGE2391> 3.0.CO; 2-V
  4. ^ A. Bauer, F. Westkämper, S. Grimme, T. Bach: Catalytic enantioselective reactions driven by photoinduced electron transfer , Nature 2005 , 436 , 1139–1140, doi: 10.1038 / nature03955 .
  5. ↑ C. Müller, A. Bauer, T. Bach: Light-driven enantioselective organocatalysis , Angew. Chem. Int. Ed. 2009 , 48 , 6640 - 6642, doi: 10.1002 / anie.200901603 , Angew. Chem. 2009 , 121 , 6767-6769, doi: 10.1002 / anie.200901603 .
  6. ^ R. Alonso, T. Bach: A Chiral Thioxanthones as an Organocatalyst for Enantioselective [2 + 2] Photocycloaddition Reactions Induced by Visible Light , Angew. Chem. Int. Ed. 2014 , 53 , 4368-4371, doi: 10.1002 / ange.201310997 , Angew. Chem. 2014 , 126 , 4457-4460, doi: 10.1002 / anie.201310997 .
  7. ↑ a b R. Brimioulle, T. Bach: Enantioselective Lewis Acid Catalysis of enones Intramolecular [2 + 2] cycloaddition Photo Reactions , Science 2013 , 342 , 840-843, doi: 10.1126 / science.1244809 .
  8. ^ S. Schröter, C. Stock, T. Bach: Regioselective cross-coupling reactions of polyhalogenated heterocycles , Tetrahedron 2005 , 61 , 2245–2267, doi: 10.1016 / j.tet.2004.11.074 .
  9. ↑ F. Mühlthau, D. Stadler, A. Goeppert, GA Olah, GKS Prakash, T. Bach: Chiral α-Branched Benzylic Carbenium Ions: Diastereoselective Intermolecular Reactions with Arene Nucleophiles and NMR-Spectroscopic Studies , J. Am. Chem. Soc. 2006 , 128 , 9668-9675, doi: 10.1021 / ja062102g .
  10. ↑ P. Selig, E. Herdtweck, T. Bach: Total Synthesis of Meloscine by a [2 + 2] -Photocycloaddition / Ring-Expansion Route , Chem. Eur. J. 2009 , 15 , 3509-3525, doi: 10.1002 / chem. 200802383
  11. ↑ O. Delgado, HM Müller, T. Bach: Concise Total Synthesis of the Thiazolyl Peptide Antibiotic GE2270 A , Chem. Eur. J. 2008 , 14 , 2322-2339, doi: 10.1002 / chem.200701823 .
  12. ^ Member entry by Thorsten Bach (with picture and CV) at the German Academy of Natural Scientists Leopoldina , accessed on May 26, 2016.
  13. ↑ Member entry by Thorsten Bach (with picture) at the Bavarian Academy of Sciences , accessed on May 26, 2016.
personal data
SURNAME Bach, Thorsten
BRIEF DESCRIPTION German chemist
DATE OF BIRTH April 15, 1965
PLACE OF BIRTH Ludwigshafen am Rhein , Rhineland-Palatinate