Ernest W. Goodpasture
Ernest William Goodpasture (born October 17, 1886 in Clarksville , Tennessee , † September 20, 1960 in Nashville , Tennessee) was an American pathologist .
Goodpasture pioneered the growth of viruses , bacteria and rickettsiae in the chick embryo and developed methods to stimulate such growth. His studies have led to a better understanding of the host-parasite relationship , opening up new possibilities for treating infectious diseases .
Life
Goodpasture earned a bachelor's degree from Vanderbilt University in Nashville, Tennessee, and an MD (medical degree) from Johns Hopkins University in Baltimore , Maryland in 1912 . He then worked with William Henry Welch and George H. Whipple in pathology there, from 1912 to 1914 as a Rockefeller Fellow . From 1915 to 1917, Goodpasture worked as a pathologist at Peter Bent Brigham Hospital in Boston , Massachusetts . In 1917 Goodpasture became Assistant Professor of Pathology at Harvard University in Cambridge , Massachusetts. In 1922 he was appointed director of the William H. Singer Memorial Research Laboratory in Pittsburgh , Pennsylvania , before becoming a professor of pathology at Vanderbilt University in Nashville , Tennessee in 1924 . He also served as dean at Vanderbilt University Medical School . In 1955 he retired , but still worked as the pathology chief scientist of the Armed Forces Institute of Pathology at the Walter Reed Military Hospital in Washington, DC
Act
In 1919, Goodpasture described a combination of glomerulonephritis and pulmonary bleeding; the condition was later called Goodpasture syndrome . McCullum-Goodpasture staining, a method for staining Gram-negative bacteria, is also named after him (and William George MacCullum ) .
In 1931 Goodpasture developed a method to cultivate viruses and rickettsiae in chicken embryos . This enabled him to produce vaccines against chickenpox , smallpox , yellow fever , typhoid , Rocky Mountains spotted fever and other pathogens that can be grown in this way.
In 1934 Goodpasture (together with CD Johnsen) was able to show that mumps is caused by a filterable virus.
Goodpasture's further work dealt with the formation of fibrinogen , with hemorrhagic pancreatitis , herpes simplex , influenza , yam disease , rabies and general questions of tumor formation.
Goodpasture was Vice Dean from 1942 to 1945 and Dean of Vanderbilt University from 1945 to 1950 . He was an editor of the American Journal of Pathology .
Awards (selection)
- 1929/1930 Harvey Lecture
- 1937 member of the National Academy of Sciences
- 1939 Honorary Doctorate from Yale University
- 1941 Honorary Doctorate from the University of Chicago
- 1943 member of the American Philosophical Society
- 1943 George M. Kober Medal
- 1946 Passano Award
- 1950 Honorary Doctorate from Washington University
- 1955 Howard Taylor Ricketts Award
- 1957 Honorary Doctorate from Tulane University , New Orleans
- 1958 Jessie Stevenson Kovalenko Medal
further reading
- JR Dawson: Ernest William Goodpasture. In: The American journal of pathology. Volume 38, February 1961, pp. 125-126, ISSN 0002-9440 . PMID 13720324 . PMC 1945009 (free full text).
- Esmond R. Long: Ernest William Goodpasture 1886-1960. In: Biographical Memoir. National Academy of Sciences , Washington 1965 (PDF, 1.5 MB)
- Robert D. Collins: Ernest William Goodpasture: Scientist, Scholar, Gentleman. Hillsboro 2002 ISBN 978-1-57736-251-7
Web links
- Harris D. Riley, Jr .: Ernest William Goodpasture in The Tennessee Encyclopedia of History and Culture ; Retrieved September 2, 2012
Individual evidence
- ^ A b Recipients of the Passano Laureate and Physician Scientist Awards. In: passanofoundation.org. Retrieved April 9, 2019 .
- ^ Heinz-Peter Schmiedebach : Goodpasture, Ernest William. In: Werner E. Gerabek , Bernhard D. Haage, Gundolf Keil , Wolfgang Wegner (eds.): Enzyklopädie Medizingeschichte. De Gruyter, Berlin / New York 2005, ISBN 3-11-015714-4 , p. 503.
- ^ Ernest William Goodpasture at whonamedit.com; Retrieved September 2, 2012
- ↑ The Harvey Lectures: Delivered under the Auspices of the Harvey Society of New York, 1929-1930, under the Patronage of the New York Academy of Medicine. JAMA , December 5, 1931
- ^ Ernest William Goodpasture at the American Philosophical Society (amphilsoc.org); Retrieved September 2, 2012
- ^ A b Medical News , JAMA , July 13, 1957
- ^ Jessie Stevenson Kovalenko Medal at the National Academy of Sciences (nasonline.org); Retrieved September 2, 2012
personal data | |
---|---|
SURNAME | Goodpasture, Ernest W. |
ALTERNATIVE NAMES | Goodpasture, Ernest; Goodpasture, Ernest William |
BRIEF DESCRIPTION | American pathologist |
DATE OF BIRTH | October 17, 1886 |
PLACE OF BIRTH | Clarksville, Tennessee |
DATE OF DEATH | 20th September 1960 |
Place of death | Nashville |