Gerald M. Rubin

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Gerald Mayer Rubin (* 1950 in Boston , Massachusetts ) is an American geneticist and molecular biologist .

Rubin has been one of the Vice Presidents of the Howard Hughes Medical Institute since 2000 and director of its Janelia Farm Research Campus since 2003 , in the planning and construction of which he was instrumental.

Life

Rubin attended Boston Latin School and earned a bachelor's degree in biology from the Massachusetts Institute of Technology (MIT) in 1971 . Among other things, he studied with Salvador Luria and took summer courses at the Cold Spring Harbor Laboratory . At the Medical Research Council (MRC) in Cambridge he acquired in 1974 a PhD to work Studies on a 5.8 S Ribosomal RNA via a yeast - RNA of 158 base pairs in length. Sydney Brenner , James Watson , Francis Crick , Fred Sanger and Max Perutz worked at the MRC at the same time as Rubin . As a postdoctoral Rubin worked at David Hogness at Stanford University , where he first gene library of Drosophila docked.

After a short stay from 1977 as an assistant professor of biology at the Sidney Farber Cancer Institute of Harvard Medical School in Boston, Rubin went to the Department of Embryology at the Carnegie Institution in Baltimore as a researcher . In 1983 Daniel Koshland brought Rubin to the University of California, Berkeley as Professor of Genetics , where he had held the Chair of Genetics since 1987 . Rubin has also been doing research for the Howard Hughes Medical Institute (HHMI) since 1987 and is also a professor of biochemistry and biophysics at the University of California, San Francisco . When Rubin became Vice President of the Howard Hughes Medical Institute in 2000, he resigned his professorship at Berkeley. At Janela Farm , Rubin (as of 2012) continues to lead his own work group.

Act

With his method of smuggling cloned genes stably into the genome of the germ cells of Drosophila , Rubin - together with Allan C. Spradling - opened up new possibilities in genetics and developmental biology. Other important works by Rubin dealt with transposons , the molecular basis of hybrid dysgenesis (see P element # hybrid dysgenesis ) and the genetic modification of Drosophila with P elements . In 1992 he founded the Drosphila genome project with Spradling , which - in collaboration with J. Craig Venter - was completed in 2000. More recent work deals with the function of Drosophila genes that have homologues in humans and with the structure and function of the Drosophila brain

Awards (selection)

Another award: Howard Taylor Ricketts Award

Web links

Individual evidence

  1. ^ The Passano Awards 1945–2011 at the Passano Foundation (passanofoundation.org); Retrieved October 11, 2012.
  2. ^ A b Newcomb Cleveland Prize Recipients at the American Association for the Advancement of Science (aaas.org); accessed on March 14, 2019.
  3. ↑ Eli Lilly Award in Biological Chemistry , winner 1935 to 2012 (PDF; 46 kB); Retrieved October 11, 2012.
  4. ^ NAS Award in Molecular Biology from the National Academy of Sciences (nasonline.org); Retrieved October 11, 2012.
  5. ↑ a b Past GSA Award Recipients at the Genetics Society of America (genetics-gsa.org); Retrieved October 11, 2012.
  6. ↑ Book of Members 1780 – present (PDF; 533 kB) of the American Academy of Arts and Sciences (amacad.org); Retrieved October 11, 2012.
  7. ↑ UC Berkeley's Gerald Rubin shares AAAS prize with Celera's Craig Venter for sequencing genome of the fruit fly at the University of California, Berkeley (berkeley.edu); Retrieved October 12, 2012.
  8. ↑ TL Orr-Weaver: The 2003 George W. Beadle Medal; Gerald M. Rubin and Allan C. Spradling. In: Genetics. Volume 164, Number 4, August 2003, pp. 1248-1249, ISSN  0016-6731 . PMID 15106662 . PMC 1462668 (free full text).
  9. ^ Foreign Members of the Royal Society (royalsociety.org); Retrieved October 11, 2012.
personal data
SURNAME Rubin, Gerald M.
ALTERNATIVE NAMES Rubin, Gerald; Rubin, Gerald Mayer (full name); Ruby, Gerry
BRIEF DESCRIPTION American molecular biologist and geneticist
DATE OF BIRTH 1950
PLACE OF BIRTH Boston