Ernest W. Goodpasture

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Ernest Goodpasture 1955

Ernest William Goodpasture (born October 17, 1886 in Clarksville , Tennessee , † September 20, 1960 in Nashville , Tennessee) was an American pathologist .

Goodpasture pioneered the growth of viruses , bacteria and rickettsiae in the chick embryo and developed methods to stimulate such growth. His studies have led to a better understanding of the host-parasite relationship , opening up new possibilities for treating infectious diseases .

Life

Goodpasture earned a bachelor's degree from Vanderbilt University in Nashville, Tennessee, and an MD (medical degree) from Johns Hopkins University in Baltimore , Maryland in 1912 . He then worked with William Henry Welch and George H. Whipple in pathology there, from 1912 to 1914 as a Rockefeller Fellow . From 1915 to 1917, Goodpasture worked as a pathologist at Peter Bent Brigham Hospital in Boston , Massachusetts . In 1917 Goodpasture became Assistant Professor of Pathology at Harvard University in Cambridge , Massachusetts. In 1922 he was appointed director of the William H. Singer Memorial Research Laboratory in Pittsburgh , Pennsylvania , before becoming a professor of pathology at Vanderbilt University in Nashville , Tennessee in 1924 . He also served as dean at Vanderbilt University Medical School . In 1955 he retired , but still worked as the pathology chief scientist of the Armed Forces Institute of Pathology at the Walter Reed Military Hospital in Washington, DC

Act

In 1919, Goodpasture described a combination of glomerulonephritis and pulmonary bleeding; the condition was later called Goodpasture syndrome . McCullum-Goodpasture staining, a method for staining Gram-negative bacteria, is also named after him (and William George MacCullum ) .

In 1931 Goodpasture developed a method to cultivate viruses and rickettsiae in chicken embryos . This enabled him to produce vaccines against chickenpox , smallpox , yellow fever , typhoid , Rocky Mountains spotted fever and other pathogens that can be grown in this way.

In 1934 Goodpasture (together with CD Johnsen) was able to show that mumps is caused by a filterable virus.

Goodpasture's further work dealt with the formation of fibrinogen , with hemorrhagic pancreatitis , herpes simplex , influenza , yam disease , rabies and general questions of tumor formation.

Goodpasture was Vice Dean from 1942 to 1945 and Dean of Vanderbilt University from 1945 to 1950 . He was an editor of the American Journal of Pathology .

Awards (selection)

further reading

Web links

Individual evidence

  1. ^ A b Recipients of the Passano Laureate and Physician Scientist Awards. In: passanofoundation.org. Retrieved April 9, 2019 .
  2. ^ Heinz-Peter Schmiedebach : Goodpasture, Ernest William. In: Werner E. Gerabek , Bernhard D. Haage, Gundolf Keil , Wolfgang Wegner (eds.): Enzyklopädie Medizingeschichte. De Gruyter, Berlin / New York 2005, ISBN 3-11-015714-4 , p. 503.
  3. ^ Ernest William Goodpasture at whonamedit.com; Retrieved September 2, 2012
  4. ↑ The Harvey Lectures: Delivered under the Auspices of the Harvey Society of New York, 1929-1930, under the Patronage of the New York Academy of Medicine. JAMA , December 5, 1931
  5. ^ Ernest William Goodpasture at the American Philosophical Society (amphilsoc.org); Retrieved September 2, 2012
  6. ^ A b Medical News , JAMA , July 13, 1957
  7. ^ Jessie Stevenson Kovalenko Medal at the National Academy of Sciences (nasonline.org); Retrieved September 2, 2012
personal data
SURNAME Goodpasture, Ernest W.
ALTERNATIVE NAMES Goodpasture, Ernest; Goodpasture, Ernest William
BRIEF DESCRIPTION American pathologist
DATE OF BIRTH October 17, 1886
PLACE OF BIRTH Clarksville, Tennessee
DATE OF DEATH 20th September 1960
Place of death Nashville