Louis K. Diamond

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Louis Klein Diamond (born May 11, 1902 in Kishinev, Russian Empire (now Chișinău , Moldova ); died June 14, 1999 in Los Angeles ) was a hematologist and pediatrician .

Life

After the Jewish pogrom in Kishinev in 1903 , his family emigrated to the United States in 1904.

Diamond grew up in New York City . He attended Harvard College from 1919 to 1923 , and graduated from Harvard Medical School in 1927 . He first worked with Florence Sabin and then completed his specialist training at Boston Children's Hospital . Here he founded one of the first hematology-pediatric research laboratories in the country.

In 1933 Diamond received a professorship at Harvard Medical School , which he held until his retirement at the age of 65 - only interrupted by his work as head of the blood donation program of the American Red Cross from 1948 to 1950. After his work at Harvard, he continued research for 20 years from the University of California, San Francisco , where he was Professor of Pediatrics, and from the University of California, Los Angeles until he was 90 .

Diamond was married with a son, biologist Jared Diamond , and a daughter.

Act

Diamond is considered the "father" of pediatric hematology . A generation of American pediatric hematologists were trained in his laboratory. The later Nobel Prize winners Daniel Carleton Gajdusek and Jean Dausset were among his students.

Together with Kenneth Blackfan published and JM Baty Diamond 1932 work under fetal erythroblastosis hitherto considered separately symptoms fetal hydrops , neonatal jaundice and kernicterus summarized. Philip Levine later discovered the cause of this clinical picture, the rhesus incompatibility . Diamond then set up a blood group laboratory in which, among other things, this disease was further researched and a test was developed to differentiate between ( placental ) IgG antibodies and (non-placental) IgM antibodies. Diamond established the exchange transfusion via the umbilical vein as a therapeutic method for the clinical picture.

Together with Blackfan, Diamond first published the Diamond-Blackfan Syndrome in 1938 . Other eponyms associated with Diamond are Gardner-Diamond syndrome ( auto-erythrocytic purpura ) and Shwachman-Bodian-Diamond syndrome .

Important results Diamond's blood group laboratories were also estimates of the frequency of illegitimate births and (together with Ernst Mayr ) the discovery that blood group characteristics are evolutionary characteristics because they predispose for or against certain diseases .

Together with Sidney Farber , Diamond is considered a pioneer in chemotherapy for childhood leukemia .

Awards (selection)

At the University of California, San Francisco , there is a professorship in hematology named after Diamond. The current job holder (as of 2016) is Yuet Wai Kan .

literature

  • Chester A. Alper, Sherwin V. Kevy, Angelyn A. Konugres: Louis K. Diamond. In: transfusion . Volume 42, 2002. pp. 1381-1382 ( PDF , 61 kB).
  • William C. Mentzer: Louis Diamond and His Contribution to Hematology. In: British Journal of Hematology . Volume 123, 2003. pp. 389-395 ( PDF , 277 kB).

Web links

Individual evidence

  1. ^ List of Past AABB Award Recipients. In: aabb.org. December 18, 2016, accessed December 18, 2016 .
  2. ↑ Book of Members 1780 – present (PDF, 517 kB) at the American Academy of Arts and Sciences (amacad.org); accessed on December 18, 2016.
  3. ^ APS Awards: John Howland Award - Past Recipients. In: aps-spr.org. Retrieved December 18, 2016 .
  4. ^ CA Janeway : Presentation of the Howland Award to Louis K. Diamond. In: Pediatric research. Volume 7, Number 10, October 1973, pp. 853-857, ISSN  0031-3998 . doi: 10.1203 / 00006450-197310000-00010 . PMID 4583724 .
  5. ^ Kan, Yuet Wai - Institute for Human Genetics at UCSF. In: humangenetics.ucsf.edu. September 10, 2013, accessed December 18, 2016 .
personal data
SURNAME Diamond, Louis K.
ALTERNATIVE NAMES Diamond, Louis; Diamond, Louis Klein
BRIEF DESCRIPTION American hematologist and pediatrician
DATE OF BIRTH May 11, 1902
PLACE OF BIRTH Kishinev , Russian Empire
DATE OF DEATH June 14, 1999
Place of death Los Angeles , United States