Yuet Wai Kan

Yuet Wai Kan (* 11. June 1936 in Hong Kong ) is a Chinese - American hematologist and geneticist at the University of California, San Francisco .

Life

Kan earned an MB, BS ( Bachelor of Medicine, Bachelor of Surgery , Degree in Medicine) from the University of Hong Kong in 1958 . He worked as an intern at Queen Mary Hospital in Hong Kong before joining the Peter Bent Brigham Hospital in Boston , Massachusetts on a 1960 scholarship . 1962/1963 he worked as an assistant doctor at the University of Pittsburgh . Research trips took him to the Massachusetts Institute of Technology (MIT) in Cambridge , Massachusetts, at the McGill University in Montreal , Canada , and the University of Pennsylvania in Philadelphia , Pennsylvania , before an assistant to David Nathan at Boston Children's Hospital was . It was there that Kan began to deal with hemoglobinopathies .

1970 Kan received a professorship (Assistant Professor) at Harvard University . In 1972 he became director of the hematology department at San Francisco General Hospital . From 1976 to 2003 Kan also conducted research for the Howard Hughes Medical Institute (HHMI). In 1977 he received a professorship in internal medicine at the University of California, San Francisco (UCSF), and in 1979 for biochemistry and biophysics . In 1980 Kan earned a D.Sc. at the University of Hong Kong. Since 1983 Kan has headed the Department of Genetics and Molecular Hematology at UCSF; he is the Louis K. Diamond Professor of Hematology.

Kan is a member of the National Academies' Committee on Human Rights .

Act

Kan is considered to be the pioneer of DNA analysis for diagnostic purposes. Kan was able to show for the first time that a single point mutation is enough to cause disease. In 1975 and 1976, together with Mitchell Golbus , he was able to obtain evidence of sickle cell anemia and thalassemia from fetal blood for the first time . Kan discovered the first DNA polymorphism in 1978 , which is now widely used in genetic analysis. In 1980 Kan published the nucleotide sequence of the two gene loci of α- hemoglobin . More recent work deals with the possibilities of gene therapy for various hemoglobinopathies.

Awards (selection)

• 1979 William Dameshek Prize from the American Society of Hematology
• 1981 Fellow of the Royal Society
• 1984 Gairdner Foundation International Award
• 1984 William Allan Memorial Award
• 1986 membership in the National Academy of Sciences
• 1986 Membership in the Academy of Sciences for the Developing World (TWAS)
• 1988 membership in the Academia Sinica
• 1989 Warren Alpert Foundation Prize
• 1990 President of the American Society of Hematology
• 1991 Albert Lasker Award for Clinical Medical Research
• 1993 membership in the American Academy of Arts and Sciences
• 1996 Foreign member of the Chinese Academy of Sciences
• 2004 Shaw Prize
• 2009 membership in the American Philosophical Society
• 2011 Karl Landsteiner Memorial Award

Web links

• Yuet Wai Kan, MD at the University of California, San Francisco (ucsf.edu); Retrieved October 6, 2011
• Research Abstract: Sickle Cell Anemia, Thalassemia, and Other Genetic Diseases at the Howard Hughes Medical Institute (hhmi.org); Retrieved October 6, 2011

Individual evidence

1. ↑ Curriculum Vitae ( Memento from March 3, 2016 in the Internet Archive ) at Chinese Child Health International (cchi.com.hk); Retrieved October 6, 2011
2. ↑ Yuet Wai Kan, MD, D.Sc. at the Howard Hughes Medical Institute (hhmi.org); Retrieved October 6, 2011
3. ↑ Yuet Wai Kan, CHR Member at the National Academies (nationalacademies.org); Retrieved October 6, 2011
4. ^ William Dameshek Prize of the American Society of Hematology (hematology.org); Retrieved October 6, 2011
5. ^ Fellows of the Royal Society (royalsociety.org); Retrieved October 6, 2011
6. ↑ Yuet Wai Kan, MD, DSc, FRCP, FRS at the Gairdner Foundation (gairdner.org); Retrieved December 8, 2012
7. ^ HH Kazazian, Jr .: The William Allan Memorial Award presented to Yuet Wai Kan . In: American Journal of Human Genetics . tape 38 , no. January 1 , 1986, ISSN  0002-9297 , pp. 1-3 , PMC 1684715 (free full text).
8. ↑ Kan Yuet Wai. In: twas.org. Retrieved February 11, 2016 . 
9. ↑ Yuet-Wai Kan at the Academia Sinica (sinica.edu.tw); Retrieved October 6, 2011
10. ↑ Yuet Wai Kan at the American Society of Hematology (hematology.org); Retrieved October 6, 2011
11. ^ Lasker Foundation: Diagnosis of genetic diseases by DNA technology - The Lasker Foundation. In: laskerfoundation.org. Accessed March 26, 2018 . 
12. ^ Foreign Members --- Academic Divisions of the Chinese Academy of Sciences. In: english.casad.cas.cn. Retrieved February 11, 2016 . 
13. ^ The Shaw Prize in Life Science and Medicine 2004 , Autobiography of Yuet-Wai Kan at the Shaw Foundation (shawprize.org); Retrieved October 6, 2011
14. ↑ Dr. Yuet Wai Kan at the American Philosophical Society (amphilsoc.org); Retrieved October 9, 2012