Michael Meyer-Hermann (physicist)

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Michael Meyer-Hermann (* 1967 in Reinbek ) is a professor at the Technical University of Braunschweig and head of the Systems Immunology department at the Helmholtz Center for Infection Research .

job

Meyer-Hermann studied physics , mathematics and philosophy in Frankfurt am Main and Paris . In 1993 he published his diploma thesis with the title “QCD sum rules with masses” on quantum chromodynamics . He received his doctorate in 1997 at the Johann Wolfgang Goethe University in Frankfurt am Main in theoretical elementary particle physics on “The inner structure of the nucleon”. In 1998 he founded the “Theoretical Biophysics” research group at the Technical University of Dresden and headed it until 2003. He spent 2004 at the University of Oxford . From 2005 to 2010 he was a fellow at the Frankfurt Institute for Advanced Studies (FIAS). Since 2010 he has been Professor at the Technical University in Braunschweig and Head of the Systems Immunology Department at the Helmholtz Center for Infection Research .

Computer modeling of the formation of mushroom-shaped structures of the bacterium Pseudomonas aeruginosa

With his working group, he develops methods in theoretical cell biology in order to understand how the adaptive immune system works and how the nervous , hormonal and immune systems interact . This includes research on T and B cells , viral and bacterial infections , metabolic disorders , diabetes, and cancer . He uses mathematical methods to model medical and biological systems. These range from ordinary and partial differential equations through agent-based modeling to algorithms for control loops and artificial intelligence .

During the COVID-19 pandemic in Germany , he and a working group from the Helmholtz Association published a model based on an extended SEIR model that was widely received. In the following weeks, regularly updated estimates of the number of reproductions in the various federal states were published. In April 2020, Meyer-Hermann spoke out in interviews and the talk show Anne Will from an epidemiological point of view against easing spatial distancing , curfews and other measures in order to keep the net reproduction number well below threshold 1 and to contain the pandemic. In a joint with u. a. Clemens Fuest ( Ifo Institute ), they showed that a reproduction factor , estimated at around 0.75, is optimal to reduce the economic effects of the pandemic without endangering the medical goals. It shows "to the extent that there is no conflict between economic and health costs in terms of a strong relaxation of measures".

Publications (selection)

  • Gabriel D. Victora, Tanja A. Schwickert, David R. Fooksman, Alice O. Kamphorst, Michael Meyer-Hermann, Michael L. Dustin, Michel C. Nussenzweig: Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter . In: Cell 143 (4), 2010, pp. 592-605, doi: 10.1016 / j.cell.2010.10.032 .
  • Gernot Schaller, Michael Meyer-Hermann: Multicellular tumor spheroid in an off-lattice Voronoi-Delaunay cell model . In: Physical Review E 71 (5), 2005, 051910, doi: 10.1103 / PhysRevE.71.051910 .
  • Jeroen MJ Tas, Luka Mesin, Giulia Pasqual, Sasha Targ, Johanne T Jacobsen, Yasuko M Mano, Casie S Chen, Jean-Claude Weill, Claude-Agnès Reynaud, Edward P Browne, Michael Meyer-Hermann, Gabriel D Victora: Visualizing antibody affinity maturation in germinal centers . In: Science 351 (6277), 2016, pp. 1048-1054, doi: 10.1126 / science.aad3439 .
  • Yang Zhang, Michael Meyer-Hermann, Laura A. George, Marc Thilo Figge, Mahmood Khan, Margaret Goodall, Stephen P. Young, Adam Reynolds, Francesco Falciani, Ari Waisman, Clare A. Notley, Michael R. Ehrenstein, Marie Kosco- Vilbois, Kai-Michael Toellner: Germinal center B cells govern their own fate via antibody feedback . In: Journal of Experimental Medicine 210 (3), 2013, pp. 457-464, doi: 10.1084 / jem.20120150 .

Web links

Individual evidence

  1. ↑ a b Our guests , website of the NDR for the TV show Anne Will on April 19, 2020.
  2. ↑ Michael Meyer-Hermann: QCD sum rules with masses , diploma thesis, Johann Wolfgang Goethe University Frankfurt am Main , 1993.
  3. ↑ Michael Meyer-Hermann: The inner structure of the nucleon: many-particle correlators and perturbation corrections in the Limes large Nf . Dissertation, Johann Wolfgang Goethe University Frankfurt am Main , 1997.
  4. ↑ a b Prof. Dr. Michael Meyer-Hermann , Helmholtz Center for Infection Research , accessed on April 20, 2020.
  5. ↑ Inaugural lecture by Prof. Dr. Michael Meyer-Hermann , press release from the Technical University of Braunschweig , May 18, 2011.
  6. ↑ Azadeh Ghanbari, Jaber Dehghany, Timo Schwebs, Mathias Müsken, Susanne Häussler, Michael Meyer-Hermann: Inoculation density and nutrient level determine the formation of mushroom-shaped structures in Pseudomonas aeruginosa biofilms . In: Scientific Reports , Volume 6, article number 32097, 2016, doi: 10.1038 / srep32097 .
  7. ↑ Michael Meyer-Hermann , Frontiers Journal Series website , accessed April 20, 2020.
  8. ↑ Arnab Bandyopadhyay et al. a .: Statement by the Helmholtz initiative “Systemic Epidemiological Analysis of the COVID-19 Epidemic” , April 13, 2020.
  9. ↑ Sahamoddin Khailaie, Tanmay Mitra, Arnab Bandyopadhyay, Marta Schips, Pietro Mascheroni, Patrizio Vanella, Berit Lange, Sebastian Binder, Michael Meyer-Hermann: Estimate of the development of the epidemic reproduction number R t from Coronavirus SARS-CoV-2 case data and implications for political measures based on prognostics , April 7, 2020, doi: 10.1101 / 2020.04.04.20053637 .
  10. ↑ Report with updated figures on the article by Khailaie et al.
  11. ↑ Florian Schumann: "Now any form of loosening would be dangerous" . In: Zeit Online , April 15, 2020.
  12. ↑ Helmholtz researchers use a number to explain why strict corona rules must remain . In: Der Tagesspiegel , April 15, 2020.
  13. ↑ Cornelia Karin Hendrich: "The reproduction number of 0.7 is an artificial effect" . In: Welt Online , accessed April 20, 2020.
  14. ↑ Florian Dorn, Sahamoddin Khailaie, Marc Stöckli, Sebastian Binder, Berit Lange, Andreas Peichl, Patrizio Vanella, Timo Wollmershäuser, Clemens Fuest , Michael Meyer-Hermann: The common interest of health and the economy: a scenario calculation to contain the corona pandemic . In: ifo Schnelldienst Digital . No. 6, 2020. Ifo Institute , Helmholtz Center for Infection Research (Ed.), May 12, 2020.
  15. ↑ Rapid easing is causing losses to the economy . In: Zeit Online , May 13, 2020.
  16. ↑ Economists and infection researchers: Careful relaxation . In: Welt Online , May 13, 2020.
personal data
SURNAME Meyer-Hermann, Michael
BRIEF DESCRIPTION German physicist, biophysicist and university professor
DATE OF BIRTH 1967
PLACE OF BIRTH Reinbek