O'nyong-nyong fever
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| A92.1 | O'Nyong-nyong fever |
| ICD-10 online (WHO version 2019) | |
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| Onyong-nyong virus | ||||||||||||||||||||
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The O'nyong-'nyong fever is a tropical viral infection and is the O'nyong-'nyong virus (officially by ICTV : Onyong-Nyong virus , ONNV) triggered. Like the Chikungunya virus and the Sindbis virus , this RNA virus belongs to the genus of the alphaviruses in the togavirus family . The name means “joint breaker” in the language of the Acholi people.
Occurrence
East and Central Africa . The virus has been found in Kenya , Malawi , Mozambique , Tanzania , Uganda , Senegal and the Central African Republic . Tourist areas are also affected. The disease occurs sporadically as an epidemic . There can often be a period of 10 to 20 years between the epidemics, with an infection rate of up to 80% in the population. The virus was first detected during a major epidemic in Uganda between 1959 and 1962. At that time, two million people fell ill. An extra-human reservoir is suspected.
transmission
O'nyong-'nyong is an arbovirus infection . It is transmitted by mosquitoes ( Anopheles gambiae and Anopheles funestus ). The mosquitoes are active at twilight , their distribution is linked to the presence of standing water .
diagnosis
Typical travel history, evidence of antibodies in the blood , clinical picture . Confusion with Chikungunya is possible.
Course of the disease and symptoms
The incubation period is 8-11 days. The disease starts suddenly with chills and a high fever , headache and lymphadenitis . There is leukopenia with relative lymphocytosis . Characteristic symptoms are the pronounced, symmetrical joint pain ( polyarthralgia ), which can persist for several weeks. Below maculopapular rash in about 60% of cases. Enanthemums of the cheek and palate mucosa can occur. Symptoms subside after two weeks. Inapparent infections (without feeling sick) are common. Long-lasting immunity remains . There are no known fatal courses.
therapy
There is no causal therapy or vaccination; treatment is symptomatic.
prevention
Consistent protection against mosquito bites: repellants , mosquito nets , light-colored, long clothing , avoidance of being outside during and after dusk .
literature
- DL Posey, T. O'rourke, JT Roehrig, RS Lanciotti, M. Weinberg, S. Maloney: O'Nyong-nyong fever in West Africa. In: Am J Trop Med Hyg. 2005 Jul; 73 (1), p. 32. PMID 16014827
- M. Bessaud, CN Peyrefitte, BA Pastorino, P. Gravier, F. Tock, F. Boete, HJ Tolou, M. Grandadam: O'nyong-nyong Virus, Chad. In: Emerg Infect Dis . 2006 Aug; 12 (8), pp. 1248-1250. PMID 16965706
Individual evidence
- ↑ ICTV Master Species List 2018b v1 MSL # 34, Feb. 2019
- ↑ a b c d ICTV: ICTV Master Species List 2019.v1 , New MSL including all taxa updates since the 2018b release, March 2020 (MSL # 35)
- ↑ O'nyong'nyong Virus , on: ScienceDirect, Source: Fenner's Veterinary Virology (Fifth Edition), 2017
- ↑ [ https://www.msdmanuals.com/de-de/profi/ Krankungen-des-rheumati-formenkreises-und-des-bewegungungsapparats/ache-in-und-an-den-gelenken/ache-in- mehreren- joints pain in multiple joints], in: Msd Manual: diseases of rheumatic and musculoskeletal, Merck Sharp & Dohme Corp.
