Stephen C. Harrison
Stephen Coplan Harrison (* 1943 in New Haven , Connecticut ) is an American biochemist and professor at Harvard University , Cambridge in Massachusetts .
Life
Harrison earned a bachelor's degree in chemistry and physics from Harvard College in 1963 and a Ph.D. from Harvard University in 1967. in biophysics . As a postdoctoral fellow , he worked with Aaron Klug at the University of Cambridge in Cambridge , England, the Lowell House at Harvard University and the Children's Cancer Research Foundation (now the Dana-Farber Cancer Institute ) in Boston , Massachusetts.
After positions at the University of Cambridge and the Children's Cancer Research Foundation , Harrison received an assistant professorship ( Assistant Professor 1971, Associate Professor 1975) in Biochemistry at Harvard University. Research and teaching stays took him to Heidelberg ( Max Planck Institute for Medical Research and Ruprecht Karls University Heidelberg ) in 1971/72 and to Cambridge ( Trinity College and Medical Research Council ) in 1977 .
Harrison has been a full professor at Harvard University since 1977, first as professor of biochemistry and molecular biology at Harvard University, and since 1996 also as professor of biochemistry and molecular pharmacology and pediatrics at Harvard Medical School . In 1996 he also became director of the Molecular Medicine Laboratory at the Boston Children's Hospital. Harrison has also been doing research for the Howard Hughes Medical Institute (HHMI) in Boston since 1987 .
Further academic positions for various institutions at Harvard University and the Harvard Medical School followed, some in managerial positions.
Act
Harrison used X-ray crystallography (crystal structure analysis ) to study viruses , DNA - protein complexes and membrane receptors . He was able to achieve decisive improvements and innovations in the methods, especially for the analysis of large macromolecules . He was the first to determine the structure of an intact virus. The combination of structural analyzes and cell biological processes led to a deeper understanding of the structure of viruses, the mechanisms of their cell entry and their assembly after replication , of the interactions between DNA and proteins and of cellular signals.
Current research deals with the mechanisms of virus replication, with clathrin- occupied vesicles and the structure and function of kinetochores .
Awards (selection)
- 1989 membership in the American Academy of Arts and Sciences
- 1990 Louisa Gross Horwitz Prize together with Michael Rossmann and Don Craig Wiley
- 1991 membership in the National Academy of Sciences
- 1997 membership in the American Philosophical Society
- 2001 Paul Ehrlich and Ludwig Darmstaedter Prize together with Michael Rossmann
- 2006 Gregori Aminoff Prize from the Royal Swedish Academy of Sciences
- 2014 Foreign member of the Royal Society
- 2015 Welch Award in Chemistry
- 2018 Rosenstiel Award
Web links
- Laboratory of Structural Cell Biology and curriculum vitae (PDF, February 2010; 312 kB) by Stephen C. Harrison at harvard.edu
- Biography and summary of the research at hhmi.org
Individual evidence
- ^ A b Members of the American Academy of Arts & Sciences: 1780-2013 "H", page 237
- ↑ Stephen C. Harrison ( memento of April 3, 2012 in the Internet Archive ) at hms.harvard.edu; Retrieved February 1, 2011.
- ^ Past Recipients of the Louisa Gross Horwitz Prize at columbia.edu; Retrieved January 30, 2011.
- ^ Goethe University - laureate since 1952. In: uni-frankfurt.de. March 14, 2016, accessed January 23, 2016 .
- ↑ Stephen C Harrison at the Royal Swedish Academy of Sciences (kva.se); Retrieved July 30, 2011.
- ↑ Professor Stephen Harrison ForMemRS at the Royal Society (royalsociety.org); accessed on May 1, 2014
| personal data | |
|---|---|
| SURNAME | Harrison, Stephen C. |
| ALTERNATIVE NAMES | Harrison, Stephen; Harrison, Stephen Coplan |
| BRIEF DESCRIPTION | American biochemist |
| DATE OF BIRTH | 1943 |
| PLACE OF BIRTH | New Haven , Connecticut |