Lonazolac: Difference between revisions

Lonazolac
Clinical data
ATC code	M01AB09 (WHO) ;
Identifiers
	IUPAC name [3-(4-chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]acetic acid;
CAS Number	53808-88-1 ;
PubChem CID	68706;
ChemSpider	61957 ;
UNII	13097143QI;
KEGG	D07265 ;
ChEBI	CHEBI:76164 ;
CompTox Dashboard (EPA)	DTXSID4046151 ;
ECHA InfoCard	100.053.428
Chemical and physical data
Formula	C17H13ClN2O2
Molar mass	312.75 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES c1ccc(cc1)n2cc(c(n2)c3ccc(cc3)Cl)CC(=O)O;
	InChI InChI=1S/C17H13ClN2O2/c18-14-8-6-12(7-9-14)17-13(10-16(21)22)11-20(19-17)15-4-2-1-3-5-15/h1-9,11H,10H2,(H,21,22) ; Key:XVUQHFRQHBLHQD-UHFFFAOYSA-N ;
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Latest revision as of 23:15, 29 January 2023

Lonazolac is a nonsteroidal anti-inflammatory drug (NSAID).

References[edit]

This drug article relating to the musculoskeletal system is a stub. You can help Wikipedia by expanding it.

@@ Line 1: / Line 1: @@
+{{Short description|Chemical compound}}
 {{Drugbox
+| Verifiedfields = changed
-| IUPAC_name        = [3-(4-chlorophenyl)-1-phenyl-1''H''-pyrazol-4-yl]acetic acid
+| Watchedfields = changed
-| image             = lonazolac.png
+| verifiedrevid = 447986412
-| CAS_number        =
+| IUPAC_name = [3-(4-chlorophenyl)-1-phenyl-1''H''-pyrazol-4-yl]acetic acid
-| ATC_prefix        = M01
+| image = lonazolac.png
-| ATC_suffix        = AB09
-| PubChem           = 68706
+<!--Clinical data-->
-| DrugBank          =
+| tradename =
+| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
+| pregnancy_US = <!-- A / B            / C / D / X -->
+| pregnancy_category =
+| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
+| legal_CA = <!--             / Schedule I, II, III, IV, V, VI, VII, VIII -->
+| legal_UK = <!-- GSL         / P       / POM / CD / Class A, B, C -->
+| legal_US = <!-- OTC                   / Rx-only  / Schedule I, II, III, IV, V -->
+| legal_status =
+| routes_of_administration =
+<!--Pharmacokinetic data-->
+| bioavailability =
+| protein_bound =
+| metabolism =
+| elimination_half-life =
+| excretion =
+<!--Identifiers-->
+| CAS_number_Ref = {{cascite|correct|CAS}}
+| CAS_number = 53808-88-1
+| ATC_prefix = M01
+| ATC_suffix = AB09
+| PubChem = 68706
+| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
+| DrugBank =
+| UNII_Ref = {{fdacite|correct|FDA}}
+| UNII = 13097143QI
+| KEGG_Ref = {{keggcite|correct|kegg}}
 | KEGG = D07265
+| ChEBI_Ref = {{ebicite|changed|EBI}}
-| C=17|H=13|Cl=1|N=2|O=2
+| ChEBI = 76164
-| molecular_weight  = 312.75032 g/mol
+| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
-| bioavailability   =
-| protein_bound     =
+| ChemSpiderID      = 61957
-| metabolism        =
+<!--Chemical data-->
-| elimination_half-life =
-| excretion         =
+| C=17 | H=13 | Cl=1 | N=2 | O=2
+| smiles            = c1ccc(cc1)n2cc(c(n2)c3ccc(cc3)Cl)CC(=O)O
-| pregnancy_AU      =  <!-- A / B1 / B2 / B3 / C / D / X -->
+| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
-| pregnancy_US      =  <!-- A / B            / C / D / X -->
+| StdInChI          = 1S/C17H13ClN2O2/c18-14-8-6-12(7-9-14)17-13(10-16(21)22)11-20(19-17)15-4-2-1-3-5-15/h1-9,11H,10H2,(H,21,22)
-| pregnancy_category=
+| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
-| legal_AU          =  <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
+| StdInChIKey       = XVUQHFRQHBLHQD-UHFFFAOYSA-N
-| legal_CA          =  <!--             / Schedule I, II, III, IV, V, VI, VII, VIII -->
-| legal_UK          =  <!-- GSL         / P       / POM / CD / Class A, B, C -->
-| legal_US          =  <!-- OTC                   / Rx-only  / Schedule I, II, III, IV, V -->
-| legal_status      =
-| routes_of_administration =
 }}
-'''Lonazolac''' is a [[non-steroidal anti-inflammatory drug]].
+'''Lonazolac''' is a [[nonsteroidal anti-inflammatory drug]] (NSAID).
+==References==
+{{Reflist|2}}
 {{Anti-inflammatory and antirheumatic products}}
+{{Prostanoidergics}}
-{{NSAIDs}}
 [[Category:Pyrazoles]]
-[[Category:Non-steroidal anti-inflammatory drugs]]
+[[Category:Nonsteroidal anti-inflammatory drugs]]
-[[Category:Organochlorides]]
+[[Category:Chloroarenes]]

v t e Non-steroidal anti-inflammatory drugs (NSAIDs) (primarily M01A and M02A, also N02BA)
pyrazolones / pyrazolidines	Aminophenazone Ampyrone Azapropazone Clofezone Difenamizole Famprofazone Feprazone Kebuzone Metamizole Mofebutazone Morazone Nifenazone Oxyphenbutazone Phenazone Phenylbutazone Propyphenazone Sulfinpyrazone Suxibuzone^‡
salicylates	Aspirin (acetylsalicylic acid)^# Aloxiprin Benorylate Carbasalate calcium Diflunisal Dipyrocetyl Ethenzamide Guacetisal Magnesium salicylate Methyl salicylate Salsalate Salicin Salicylamide Salicylic acid (salicylate) Sodium salicylate
acetic acid derivatives and related substances	Aceclofenac Acemetacin Alclofenac Amfenac Bendazac Bromfenac Bufexamac Bumadizone Diclofenac Difenpiramide Etodolac Felbinac Fenclozic acid Fentiazac Indometacin Indometacin farnesil Isoxepac Ketorolac Lonazolac Mofezolac Oxametacin Prodolic acid Proglumetacin Sulindac Tiopinac Tolmetin Zomepirac^†
oxicams	Ampiroxicam Droxicam Isoxicam Lornoxicam Meloxicam Piroxicam Pivoxicam Tenoxicam
propionic acid derivatives (profens)	Alminoprofen Benoxaprofen^† Carprofen^‡ Dexibuprofen Dexketoprofen Fenbufen Fenoprofen Flunoxaprofen Flurbiprofen Ibuprofen^# Ibuproxam Indoprofen^† Ketoprofen Loxoprofen Miroprofen Naproxen Oxaprozin Pelubiprofen Piketoprofen Pirprofen Suprofen Tarenflurbil Tepoxalin^‡ Tiaprofenic acid Vedaprofen^‡ Zaltoprofen COX-inhibiting nitric oxide donator: Naproxcinod
n-arylanthranilic acids (fenamates)	Azapropazone Clonixin Etofenamate Floctafenine Flufenamic acid Flunixin Flutiazin Glafenine^† Meclofenamic acid Mefenamic acid Morniflumate Niflumic acid Tolfenamic acid
COX-2 inhibitors (coxibs)	Apricoxib Celecoxib (+tramadol) Cimicoxib^‡ Deracoxib^‡ Etoricoxib Firocoxib^‡ Lumiracoxib^† Mavacoxib^‡ Parecoxib Robenacoxib^‡ Rofecoxib^† Valdecoxib^†
other	Aminopropionitrile Benzydamine Chondroitin sulfate Diacerein Fluproquazone Glucosamine Glycosaminoglycan Hyperforin Nabumetone Nimesulide Oxaceprol Proquazone Superoxide dismutase / orgotein Tenidap
NSAID combinations	Ibuprofen/famotidine Ibuprofen/hydrocodone Ibuprofen/oxycodone Ibuprofen/paracetamol Meloxicam/bupivacaine Naproxen/diphenhydramine Naproxen/esomeprazole
Key: underline indicates initially developed first-in-class compound of specific group; ^#WHO-Essential Medicines; ^†withdrawn drugs; ^‡veterinary use.
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