1,4-dichloro-2-nitrobenzene

Structural formula
General
Surname	1,4-dichloro-2-nitrobenzene
other names	2,5-dichloro-1-nitrobenzene
Molecular formula	C 6 H 3 Cl 2 NO 2
Brief description	yellow solid with a slightly aromatic odor
External identifiers / databases
CAS number 89-61-2 EC number 201-923-3 ECHA InfoCard 100.001.749 PubChem 6977 ChemSpider 21111865 Wikidata Q18818937
properties
Molar mass	192.00 g mol −1
Physical state	firmly
density	1.6 g cm −3
Melting point	56 ° C
boiling point	267 ° C
Vapor pressure	0.51 Pa (25 ° C)
solubility	practically insoluble in water (83 mg l −1 at 20 ° C) soluble in ethanol, ether, benzene and carbon disulfide Easily soluble in carbon tetrachloride
safety instructions
GHS labeling of hazardous substances Caution H and P phrases H: 302-411 P: 301 + 312 + 330
Toxicological data	1000 mg kg −1 ( LD 50 ,  rat ,  oral )
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

1,4-dichloro-2-nitrobenzene is a chemical compound from the group of aromatic nitro compounds .

Extraction and presentation

1,4-dichloro-2-nitrobenzene can be prepared by nitration of 1,4-dichlorobenzene are recovered.

properties

1,4-dichloro-2-nitrobenzene is a crystalline, yellow, hardly inflammable, combustible solid with a slightly aromatic odor, which is practically insoluble in water. It decomposes when heated, producing hydrogen chloride , nitrogen oxides , carbon monoxide and carbon dioxide .

use

1,4-dichloro-2-nitrobenzene is used in the manufacture of drugs , pesticides , dyes and in the synthesis of lysophosphatidic acid acyltransferase β inhibitors. 4-chloro-2-nitrophenol can be obtained by reaction with a sodium hydroxide solution at 145 ° C.

Individual evidence

1. ↑ ^{a b c d e f g h i j} Entry on 1,4-dichloro-2-nitrobenzene in the GESTIS substance database of the IFA , accessed on January 9, 2019(JavaScript required) .
2. ↑ ^{a b} OECD : Screening Information Dataset (SIDS) Initial Assessment Report (SIAR) for Benzene, 1,4-dichloro-2-nitro- , accessed on January 1, 2017.
3. ↑ ^{a b c} data sheet 1,4-dichloro-2-nitrobenzene, 98% from AlfaAesar, accessed on January 1, 2017 ( PDF )(JavaScript required) .
4. ↑ Entry on 1,4-dichloro-2-nitrobenzene in the Hazardous Substances Data Bank , accessed on January 1, 2017.
5. ↑ PrepChem.com: Synthesis of 4-chloro-2-nitrophenol - PrepChem.com , accessed February 10, 2019.