Kendall Houk

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Kendall Houk

Kendall Newcomb Houk (born February 27, 1943 in Nashville , Tennessee ) is an American chemist .

Life

Kendall Houk was born to Charles H. and Janet Houk. He studied at Harvard University , where he received a Bachelor of Arts in 1964 , a Master of Science in 1966 and a Ph.D. in 1968. acquired. In his doctoral thesis supervised by Robert B. Woodward , he experimentally tested selection rules for the (6 + 4) cycloaddition . He then went to Louisiana State University and was there from 1968 to 1972 Assistant Professor , 1972 to 1975 Associate Professor and 1975 to 1980 Professor of Chemistry. From 1980 to 1985 he worked as a chemistry professor at the University of Pittsburgh and since 1986 at the University of California, Los Angeles . There he headed the Faculty of Chemistry and Biochemistry from 1991 to 1994. Since 2009 he has held the Saul Winstein Chair for Organic Chemistry. He was also director of the chemistry division of the National Science Foundation from 1988 to 1990 .

Houk works in the fields of theoretical chemistry and organic computational chemistry . His working group models complex organic reactions on the computer and tests the theoretical predictions experimentally. His interests include the design of artificial enzymes as catalyst of chemical reactions, the quantitative modeling of stereoselective reactions and the dynamics of pericyclic reactions .

He is married and has one child. His hobbies are running, cycling, swimming, art and music.

Awards

Memberships

Works

In addition to more than 900 magazine articles, he published:

literature

Web links

Commons : Kendall Houk  - collection of images, videos and audio files

Individual evidence

  1. ↑ biographical data, publications and Academic pedigree of Kendall N. Houk at academictree.org, accessed on February 12 2018th
  2. ↑ Daniela Röthlisberger, Olga Khersonsky, Andrew M. Wollacott, Lin Jiang, Jason DeChancie, Jamie Betker, Jasmine L. Gallaher, Eric A. Althoff, Alexandre Zanghellini, Orly Dym, Shira Albeck, Kendall N. Houk, Dan S. Tawfik and David Baker: Kemp Elimination Catalysts by Computational Enzyme Design. In: Nature . Volume 453, May 8, 2008, pp. 190-195, doi: 10.1038 / nature06879 ; Lin Jiang, Eric A. Althoff, Fernando R. Clemente, Lindsey Doyle, Daniela Röthlisberger, Alexandre Zanghellini, Jasmine L. Gallaher, Jamie L. Betker, Fujie Tanaka, Carlos F. Barbas III, Donald Hilvert , Kendall N. Houk, Barry L. Stoddard and David Baker: De Novo Computational Design of Retro-Aldol Enzymes. In: Science . Volume 319, No. 5868, March 7, 2008, pp. 1387-1391, doi: 10.1126 / science.1152692
  3. ↑ Nelson G. Rondan and KN Houk: Theory of Stereoselection in Conrotatory Electrocyclic Reactions of Substituted Cyclobutenes. In: Journal of the American Chemical Society . Volume 107, No. 7, April 1985, pp. 2099-2111, doi: 10.1021 / ja00293a046 ; KN Houk, MN Paddon-Row, NG Rondan, YD Wu, FK Brown, DC Spellmeyer, JT Metz, Y. Li and RJ Loncharich: Theory and Modeling of Stereoselective Organic Reactions. In: Science. Volume 231, No. 4742, March 7, 1986, pp. 1108-1117, doi: 10.1126 / science.3945819 ; Justin B. Siegel, Alexandre Zanghellini, Helena M. Lovick, Gert Kiss, Abigail R. Lambert, Jennifer L. St. Clair, Jasmine L. Gallaher, Donald Hilvert, Michael H. Gelb, Barry L. Stoddard, Kendall N. Houk , Forrest E. Michael and David Baker: Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction. In: Science. Volume 329, No. 5989, July 16, 2010, pp. 309-313, doi: 10.1126 / science.1190239
  4. ↑ Kendall N. Houk: Frontier Molecular Orbital Theory of Cycloaddition Reactions. In: Accounts of Chemical Research . Volume 8, No. 11, November 1975, pp. 361-369, doi: 10.1021 / ar50095a001 ; Kendall N. Houk, Yi Li and Jeffrey D. Evanseck: Transition Structures of Hydrocarbon Pericyclic Reactions. In: Angewandte Chemie International Edition in English . Volume 31, No. 6, June 1992, pp. 682-708, doi: 10.1002 / anie.199206821 ; Kendall N. Houk, Javier González, and Yi Li: Pericyclic Reaction Transition States: Passions and Punctilios, 1935–1995. In: Accounts of Chemical Research. Volume 28, No. 2, 1995, pp. 81-90, doi: 10.1021 / ar00050a004 ; Daniel H. Ess and KN Houk: Theory of 1,3-Dipolar Cycloadditions: Distortion / Interaction and Frontier Molecular Orbital Models. In: Journal of the American Chemical Society . Volume 130, No. 31, 2008, pp. 10187-10198, doi: 10.1021 / ja800009z
personal data
SURNAME Houk, Kendall
ALTERNATIVE NAMES Houk, Kendall Newcomb (full name)
BRIEF DESCRIPTION American chemist
DATE OF BIRTH February 27, 1943
PLACE OF BIRTH Nashville , Tennessee