Santana (family name)
Santana is a family name .
Name bearer
- Adria Santana Rodríguez (1948–2011), Cuban actress
- Ana de Santana (* 1960), Angolan poet and writer
- Angel Santana (* 1977), Spanish basketball player
- Carlos Santana (* 1947), American musician of Mexican origin
- Carlos Santana (soccer player) (* 1953), Costa Rican soccer player and coach
- Carlos Santana (baseball player) (* 1986), Dominican baseball player
- Cléber Santana (1981-2016), Brazilian soccer player
- Cremilda Santana (born 1946), Brazilian actress
- Daneysha Santana (* 1994), Puerto Rican badminton player
- Domingo Santana (* 1992), Dominican baseball player
- Ervin Santana (* 1982), Dominican baseball player
- Federico Santana (* 1987), Uruguayan weightlifter
- Felipe Santana (* 1986), Brazilian soccer player
- Fidelis Júnior Santana da Silva (* 1981), Brazilian soccer player
- Francis Santana (1929-2014), Dominican singer
- Francisco Antunes Santana (1924–1982), Portuguese clergyman, Roman Catholic bishop of Funchal
- Frantoni Santana , Dominican songwriter
- Gabriel Santana Pinto (* 1990), Brazilian soccer player
- George Santana , South African racing car driver
- Joel Santana (* 1948), Brazilian soccer player and coach
- Johan Santana (* 1979), Venezuelan baseball player
- Jonathan Santana (* 1981), Argentine-Paraguayan soccer player
- Jorge Santana (* 1954), Mexican musician
- José Edson Santana de Oliveira (* 1952), Brazilian clergyman, Bishop of Eunápolis
- José Roberto Gomes-Santana (* 1978; Zé Roberto ), Brazilian soccer player, see Zé Roberto (soccer player, 1978)
- Juelz Santana (* 1982), American rapper
- Julien Santana , Brazilian soccer player
- Julio Santana (* 1973), former Dominican baseball pitcher
- Lee Santana (* 1959), American lutenist and composer
- Luan Santana (* 1991), Brazilian Latin singer
- Luis Santana (* 1958), Dominican boxer
- Manuel Santana (* 1938), Spanish tennis player
- María de los Ángeles Santana (1914–2011), Cuban actress
- Mario Santana (* 1981), Argentinian soccer player
- Merlin Santana (1976-2002), American actor
- Michel dos Reis Santana (* 1977), Brazilian soccer player
- Nino Konis Santana (1957–1998), East Timorese freedom fighter and politician
- Norberto Santana Jr. , Dominican journalist
- Norberto Santana (painter) (* 1943), Dominican painter
- Pedro Santana (1801–1864), Dominican politician, president between 1844 and 1861
- Pedro Santana Lopes (* 1956), Portuguese politician (PSD)
- Pedro de Santana Rocha († 2020), Brazilian journalist and reporter
- Pedro Aparecido Santana (* 1973), Brazilian soccer player
- Reginaldo de Santana (* 1975), Brazilian soccer player
- Rodrigo Santana (* 1979), Brazilian volleyball player
- Salvador Santana (* 1983), American musician
- Sergio Santana (* 1979), Mexican soccer player
- Sixto Batista Santana († 2014), Cuban military and politician
- Telê Santana (1931–2006), Brazilian football player and coach
- Tito Santana (* 1953), American-Mexican professional wrestler
- Ubaldo Santana (* 1941), Venezuelan religious, Archbishop of Maracaibo
- Vasco Santana (1898-1958), Portuguese actor
- Victor Hugo Santana Carvalho (* 1998), Brazilian soccer player, see Vitinho (soccer player, March 1998)
- Viviane de Santana Paulo (* 1966), German-Brazilian writer
- Willians dos Santos Santana (* 1988), Brazilian soccer player