Thomas Jessell

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Thomas Michael Jessell (born August 2, 1951 in London - † April 28, 2019 ) was a British developmental and neurobiologist at the Kavli Institute for Brain Science at Columbia University in New York City .

Life

Jessell acquired at the Chelsea College of the University of London with a degree in pharmacology and in 1977 at the British University of Cambridge a Ph.D. in Neuropharmacology with a work on the substance P . As a postdoc , he worked with Gerald Fischbach at Harvard Medical School, among others . 1981 Jessell received a first professorship (assistant professor) for neurobiology at Harvard University in Cambridge , Massachusetts. There he was, among other things, the doctoral supervisor of Thomas Reardon . From 1985 he was a professor at Columbia University in New York City, where he also conducted research for the Howard Hughes Medical Institute (HHMI).

Act

Jessell's research revolutionized the understanding of the development of the central nervous system of vertebrates at the molecular level. He was able to show how cells in different parts of the embryo are fixed in a certain position in the body and how the cells then defined as nerve cells behave differently depending on their position. He made a significant contribution to the elucidation of the development of serious congenital malformations of the brain and spinal cord . Jessell built a bridge between developmental biology and neurobiology . He was part of the international group of researchers who identified the three mammalian genes that code for proteins in the hedgehog signaling pathway ( sonic hedgehog , Indian hedgehog, and desert hedgehog ).

Awards (selection)

Fonts (selection)

literature

Web links

Individual evidence

  1. Obituary
  2. Jump up ↑ Thomas Jessell, prominent neuroscientist and former director of the Zuckerman Mind Brain Behavior Institute, is dead. In: columbiaspectator.com. April 30, 2019, accessed May 29, 2020 .
  3. Book of Members 1780 – present (PDF, 96 kB) of the American Academy of Arts and Sciences (amacad.org); Retrieved March 25, 2012
  4. ^ NAS Award for Scientific Reviewing at the National Academy of Sciences (nasonline.org); accessed on January 13, 2016
  5. ^ Fellows of the Royal Society (royalsociety.org); Retrieved March 25, 2012
  6. March of Dimes Prize in Developmental Biology - Previous Recipients ( Memento from February 13, 2009 in the Internet Archive )
  7. Thomas Jessell. In: kavliprize.org. Retrieved February 13, 2016 .
  8. Thomas M. Jessel Ph.D. at the Gairdner Foundation (gairdner.org); Retrieved August 7, 2012
  9. 2014 Gruber Neuroscience Prize at the Gruber Foundation (gruber.yale.edu); Retrieved June 6, 2014
  10. Medisinske fag in the Norwegian Academy of Sciences (dnva.no); Retrieved March 25, 2012