Karl Zipf

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Karl Eduard Zipf (born January 1, 1895 in Oberkirch (Baden) , † March 22, 1990 in Mannheim-Neckarau ) was a German doctor and pharmacologist .

Life

Karl Eduard Zipf's parents were an Oberkirch watchmaker of the same name from Schopfheim († 1923) and his wife Luise geb. Violinist. Even today (2014) there is a watch shop in the Oberkircher house at Hauptstrasse 47, which his father bought. A younger brother, Hans Friedrich Zipf , also became a pharmacologist. After attending grammar school in Offenburg , Karl Eduard studied medicine in Strasbourg , Würzburg and Heidelberg . During his studies in 1914 he became a member of the Strasbourg fraternity Arminia , from which he left in 1919. In 1921 he was promoted to Dr. med. PhD . From 1923 he worked at the Pharmacological Institute of the Ruprecht-Karls-Universität Heidelberg with Rudolf Gottlieb , from 1924 at the Pharmacological Institute of the University of Münster with Hermann Freund . There he completed his habilitation in 1926. In 1933 he was appointed to the chair of pharmacology at the University of Königsberg as the successor to Fritz Eichholtz , which he held until the end of World War II . From 1934 to 1947 he was a member of the board of the German Pharmacological Society . After the war, he first worked in the pharmaceutical industry and at the German Drug Testing Institute in Munich . In 1954 he took over the chair for pharmacology, toxicology and pharmacy at the veterinary faculty of the Ludwig Maximilians University in Munich . From 1957 to 1961 he was dean of his faculty. In 1963 he retired , but temporarily headed the institute until 1970.

research

During his time in Heidelberg, Zipf investigated substances that had an effect on the circulation, including adenosine , which was then used as a substance to expand blood vessels. In Königsberg he tested the antagonism of analeptics , substances that stimulate the central nervous system, to sleeping pills and anesthetics such as hexobarbital . He found pentetrazole or Cardiazol ® to be the most useful antidote . Today analeptics are obsolete. Circulatory active substances such as reserpine and ajmaline were again the subject of research in Munich.

Honors

In 1961, the veterinary faculty in Munich awarded Zipf an honorary doctorate . Shortly before his 70th birthday, he received the Bavarian Order of Merit on December 7, 1964 .

literature

  • H. Greim: Prof. Dr. Dr. hc Karl Zipf. In: Communications from the German Society for Pharmacology and Toxicology. 8, 1991, pp. 10-11.
  • Jürgen Lindner, Heinz Lüllmann: Pharmacological institutes and biographies of their directors. Editio Cantor, Aulendorf 1996, ISBN 3-87193-172-1 .
  • Harry Scholz, Paul Schroeder: Pharmacological Institute, Medical Faculty of the Albertus University in Königsberg / Pr. In: Athineos Philippu (Ed.): History and work of the pharmacological, clinical-pharmacological and toxicological institutes in German-speaking countries. Volume 3. Supplement. Berenkamp-Verlag, Innsbruck 2011, ISBN 978-3-85093-281-3 , pp. 190-192.
  • Rüdiger Schulz: Institute for Pharmacology, Toxicology and Pharmacy, Veterinary Faculty of the Ludwig Maximilians University in Munich. In: Athineos Philippu (Ed.): History and work of the pharmacological, clinical-pharmacological and toxicological institutes in German-speaking countries. Berenkamp-Verlag, Innsbruck 2004, ISBN 3-85093-180-3 , pp. 536-541.

Individual evidence

  1. ↑ a b Message from the Oberkirch City Archives to user: Coranton . The indication "Leutershausen an der Bergstrasse" as the place of death in Greim as well as Lindner and Lüllmann, s. Literature is wrong.
  2. ^ Paul Wentzcke : Fraternity lists. Second volume: Strasbourg - The Strasbourg Burschenschaft 1880 to 1918. Görlitz 1942, The Arminia Burschenschaft (1886) No. 198.
  3. ↑ Ferdinand Schlemmer: German Drug Testing Institute. In: Pharmazeutische Zeitung 108, 1963, pp. 1319-1325.
  4. ↑ Karl Zipf: About the physiological and pharmacological importance of circulatory, intermediate metabolic products . In: Clinical weekly . tape 10 , no. 33 , 1931, pp. 1521-1523 , doi : 10.1007 / BF01735215 .
  5. ↑ K. Zipf, W. Giese: About the effect of adenosine-like substances and some organ extracts on the capillaries . In: Naunyn-Schmiedeberg's archive for experimental pathology and pharmacology . tape 171 , 1933, pp. 111-118 , doi : 10.1007 / BF01981253 .
  6. ↑ K. Zipf, WA Windschus, F. Kokoschka: On the effect of Cardiazol, Coramin, Hexeton, Strychnin and Ikoral against narcotics . In: Naunyn-Schmiedeberg's archive for experimental pathology and pharmacology . tape 185 , 1937, pp. 113-124 , doi : 10.1007 / BF01865312 .
  7. ↑ K. Zipf: On the pharmacology of Rauwolfia alkaloids more effective in blood pressure . In: drug research . tape 7 , 1957, pp. 475-477 .
  8. ^ Alfred Petter, Karl Zipf: On the antifibrillary action of ajmaline, bromine-ajmaline, quinidine and novocainamide on the heart . In: Naunyn-Schmiedeberg's archive for experimental pathology and pharmacology . tape 243 , 1962, pp. 519-527 , doi : 10.1007 / BF00244950 .
personal data
SURNAME Zipf, Karl
ALTERNATIVE NAMES Zipf, Karl Eduard (full name)
BRIEF DESCRIPTION German doctor and pharmacologist
DATE OF BIRTH January 1, 1895
PLACE OF BIRTH Oberkirch (Baden)
DATE OF DEATH March 22, 1990
Place of death Mannheim-Neckarau