Equilibrative nucleoside transporter 2: Difference between revisions

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'''Equilibrative nucleoside transporter 2''' ('''ENT2''') is a [[protein]] that in humans is encoded by the ''SLC29A2'' [[gene]].<ref name="pmid9192854">{{cite journal | author = Williams JB, Rexer B, Sirripurapu S, John S, Goldstein R, Phillips JA 3rd, Haley LL, Sait SN, Shows TB, Smith CM, Gerhard DS | title = The human HNP36 gene is localized to chromosome 11q13 and produces alternative transcripts that are not mutated in multiple endocrine neoplasia, type 1 (MEN I) syndrome | journal = Genomics | volume = 42 | issue = 2 | pages = 325–30 |date=Sep 1997 | pmid = 9192854 | pmc = | doi = 10.1006/geno.1997.4751 }}</ref><ref name="pmid9478986">{{cite journal | author = Crawford CR, Patel DH, Naeve C, Belt JA | title = Cloning of the human equilibrative, nitrobenzylmercaptopurine riboside (NBMPR)-insensitive nucleoside transporter ei by functional expression in a transport-deficient cell line | journal = J Biol Chem | volume = 273 | issue = 9 | pages = 5288–93 |date=Mar 1998 | pmid = 9478986 | pmc = | doi = 10.1074/jbc.273.9.5288}}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SLC29A2 solute carrier family 29 (nucleoside transporters), member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3177| accessdate = }}</ref>
'''Equilibrative nucleoside transporter 2''' ('''ENT2''') is a [[protein]] that in humans is encoded by the ''SLC29A2'' [[gene]].<ref name="pmid9192854">{{cite journal | vauthors = Williams JB, Rexer B, Sirripurapu S, John S, Goldstein R, ((Phillips JA 3rd)), Haley LL, Sait SN, Shows TB, Smith CM, Gerhard DS | title = The human HNP36 gene is localized to chromosome 11q13 and produces alternative transcripts that are not mutated in multiple endocrine neoplasia, type 1 (MEN I) syndrome | journal = Genomics | volume = 42 | issue = 2 | pages = 325–30 |date=Sep 1997 | pmid = 9192854 | pmc = | doi = 10.1006/geno.1997.4751 }}</ref><ref name="pmid9478986">{{cite journal | vauthors = Crawford CR, Patel DH, Naeve C, Belt JA | title = Cloning of the human equilibrative, nitrobenzylmercaptopurine riboside (NBMPR)-insensitive nucleoside transporter ei by functional expression in a transport-deficient cell line | journal = J Biol Chem | volume = 273 | issue = 9 | pages = 5288–93 |date=Mar 1998 | pmid = 9478986 | pmc = | doi = 10.1074/jbc.273.9.5288}}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SLC29A2 solute carrier family 29 (nucleoside transporters), member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3177| accessdate = }}</ref>


== See also ==
== See also ==
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{{PBB_Further_reading
| citations =
| citations =
*{{cite journal | author=Baldwin SA, Beal PR, Yao SY |title=The equilibrative nucleoside transporter family, SLC29. |journal=Pflugers Arch. |volume=447 |issue= 5 |pages= 735–43 |year= 2004 |pmid= 12838422 |doi= 10.1007/s00424-003-1103-2 |display-authors=etal}}
*{{cite journal | vauthors=Baldwin SA, Beal PR, Yao SY |title=The equilibrative nucleoside transporter family, SLC29. |journal=Pflugers Arch. |volume=447 |issue= 5 |pages= 735–43 |year= 2004 |pmid= 12838422 |doi= 10.1007/s00424-003-1103-2 |display-authors=etal}}
*{{cite journal | author=Mangravite LM, Badagnani I, Giacomini KM |title=Nucleoside transporters in the disposition and targeting of nucleoside analogs in the kidney. |journal=Eur. J. Pharmacol. |volume=479 |issue= 1-3 |pages= 269–81 |year= 2004 |pmid= 14612157 |doi=10.1016/j.ejphar.2003.08.076 }}
*{{cite journal | vauthors=Mangravite LM, Badagnani I, Giacomini KM |title=Nucleoside transporters in the disposition and targeting of nucleoside analogs in the kidney. |journal=Eur. J. Pharmacol. |volume=479 |issue= 1-3 |pages= 269–81 |year= 2004 |pmid= 14612157 |doi=10.1016/j.ejphar.2003.08.076 }}
*{{cite journal | author=Williams JB, Lanahan AA |title=A mammalian delayed-early response gene encodes HNP36, a novel, conserved nucleolar protein. |journal=Biochem. Biophys. Res. Commun. |volume=213 |issue= 1 |pages= 325–33 |year= 1995 |pmid= 7639753 |doi= 10.1006/bbrc.1995.2133 }}
*{{cite journal | vauthors=Williams JB, Lanahan AA |title=A mammalian delayed-early response gene encodes HNP36, a novel, conserved nucleolar protein. |journal=Biochem. Biophys. Res. Commun. |volume=213 |issue= 1 |pages= 325–33 |year= 1995 |pmid= 7639753 |doi= 10.1006/bbrc.1995.2133 }}
*{{cite journal | author=Griffiths M, Yao SY, Abidi F |title=Molecular cloning and characterization of a nitrobenzylthioinosine-insensitive (ei) equilibrative nucleoside transporter from human placenta. |journal=Biochem. J. |volume=328 |issue= 3|pages= 739–43 |year= 1998 |pmid= 9396714 |doi= |pmc=1218980|display-authors=etal}}
*{{cite journal | vauthors=Griffiths M, Yao SY, Abidi F |title=Molecular cloning and characterization of a nitrobenzylthioinosine-insensitive (ei) equilibrative nucleoside transporter from human placenta. |journal=Biochem. J. |volume=328 |issue= 3|pages= 739–43 |year= 1998 |pmid= 9396714 |doi= |pmc=1218980|display-authors=etal}}
*{{cite journal | author=Yao SY, Ng AM, Vickers MF |title=Functional and molecular characterization of nucleobase transport by recombinant human and rat equilibrative nucleoside transporters 1 and 2. Chimeric constructs reveal a role for the ENT2 helix 5-6 region in nucleobase translocation. |journal=J. Biol. Chem. |volume=277 |issue= 28 |pages= 24938–48 |year= 2002 |pmid= 12006583 |doi= 10.1074/jbc.M200966200 |display-authors=etal}}
*{{cite journal | vauthors=Yao SY, Ng AM, Vickers MF |title=Functional and molecular characterization of nucleobase transport by recombinant human and rat equilibrative nucleoside transporters 1 and 2. Chimeric constructs reveal a role for the ENT2 helix 5-6 region in nucleobase translocation. |journal=J. Biol. Chem. |volume=277 |issue= 28 |pages= 24938–48 |year= 2002 |pmid= 12006583 |doi= 10.1074/jbc.M200966200 |display-authors=etal}}
*{{cite journal | author=Molina-Arcas M, Bellosillo B, Casado FJ |title=Fludarabine uptake mechanisms in B-cell chronic lymphocytic leukemia. |journal=Blood |volume=101 |issue= 6 |pages= 2328–34 |year= 2003 |pmid= 12411296 |doi= 10.1182/blood-2002-07-2236 |display-authors=etal}}
*{{cite journal | vauthors=Molina-Arcas M, Bellosillo B, Casado FJ |title=Fludarabine uptake mechanisms in B-cell chronic lymphocytic leukemia. |journal=Blood |volume=101 |issue= 6 |pages= 2328–34 |year= 2003 |pmid= 12411296 |doi= 10.1182/blood-2002-07-2236 |display-authors=etal}}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 |pmc=139241|display-authors=etal}}
*{{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 |pmc=139241|display-authors=etal}}
*{{cite journal | author=Mangravite LM, Xiao G, Giacomini KM |title=Localization of human equilibrative nucleoside transporters, hENT1 and hENT2, in renal epithelial cells. |journal=Am. J. Physiol. Renal Physiol. |volume=284 |issue= 5 |pages= F902–10 |year= 2003 |pmid= 12527552 |doi= 10.1152/ajprenal.00215.2002 }}
*{{cite journal | vauthors=Mangravite LM, Xiao G, Giacomini KM |title=Localization of human equilibrative nucleoside transporters, hENT1 and hENT2, in renal epithelial cells. |journal=Am. J. Physiol. Renal Physiol. |volume=284 |issue= 5 |pages= F902–10 |year= 2003 |pmid= 12527552 |doi= 10.1152/ajprenal.00215.2002 }}
*{{cite journal | author=Ward JL, Leung GP, Toan SV, Tse CM |title=Functional analysis of site-directed glycosylation mutants of the human equilibrative nucleoside transporter-2. |journal=Arch. Biochem. Biophys. |volume=411 |issue= 1 |pages= 19–26 |year= 2003 |pmid= 12590919 |doi=10.1016/S0003-9861(02)00718-X }}
*{{cite journal | vauthors=Ward JL, Leung GP, Toan SV, Tse CM |title=Functional analysis of site-directed glycosylation mutants of the human equilibrative nucleoside transporter-2. |journal=Arch. Biochem. Biophys. |volume=411 |issue= 1 |pages= 19–26 |year= 2003 |pmid= 12590919 |doi=10.1016/S0003-9861(02)00718-X }}
*{{cite journal | author=Szkotak AJ, Ng AM, Man SF |title=Coupling of CFTR-mediated anion secretion to nucleoside transporters and adenosine homeostasis in Calu-3 cells. |journal=J. Membr. Biol. |volume=192 |issue= 3 |pages= 169–79 |year= 2003 |pmid= 12820662 |doi=10.1007/s00232-002-1073-x |display-authors=etal}}
*{{cite journal | vauthors=Szkotak AJ, Ng AM, Man SF |title=Coupling of CFTR-mediated anion secretion to nucleoside transporters and adenosine homeostasis in Calu-3 cells. |journal=J. Membr. Biol. |volume=192 |issue= 3 |pages= 169–79 |year= 2003 |pmid= 12820662 |doi=10.1007/s00232-002-1073-x |display-authors=etal}}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
*{{cite journal | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
*{{cite journal | author=Farré X, Guillén-Gómez E, Sánchez L |title=Expression of the nucleoside-derived drug transporters hCNT1, hENT1 and hENT2 in gynecologic tumors. |journal=Int. J. Cancer |volume=112 |issue= 6 |pages= 959–66 |year= 2004 |pmid= 15386342 |doi= 10.1002/ijc.20524 |display-authors=etal}}
*{{cite journal | vauthors=Farré X, Guillén-Gómez E, Sánchez L |title=Expression of the nucleoside-derived drug transporters hCNT1, hENT1 and hENT2 in gynecologic tumors. |journal=Int. J. Cancer |volume=112 |issue= 6 |pages= 959–66 |year= 2004 |pmid= 15386342 |doi= 10.1002/ijc.20524 |display-authors=etal}}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 |pmc=528928|display-authors=etal}}
*{{cite journal | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 |pmc=528928|display-authors=etal}}
*{{cite journal | author=Visser F, Zhang J, Raborn RT |title=Residue 33 of human equilibrative nucleoside transporter 2 is a functionally important component of both the dipyridamole and nucleoside binding sites. |journal=Mol. Pharmacol. |volume=67 |issue= 4 |pages= 1291–8 |year= 2005 |pmid= 15644498 |doi= 10.1124/mol.104.005884 |display-authors=etal}}
*{{cite journal | vauthors=Visser F, Zhang J, Raborn RT |title=Residue 33 of human equilibrative nucleoside transporter 2 is a functionally important component of both the dipyridamole and nucleoside binding sites. |journal=Mol. Pharmacol. |volume=67 |issue= 4 |pages= 1291–8 |year= 2005 |pmid= 15644498 |doi= 10.1124/mol.104.005884 |display-authors=etal}}
*{{cite journal | author=Visser F, Baldwin SA, Isaac RE |title=Identification and mutational analysis of amino acid residues involved in dipyridamole interactions with human and Caenorhabditis elegans equilibrative nucleoside transporters. |journal=J. Biol. Chem. |volume=280 |issue= 12 |pages= 11025–34 |year= 2005 |pmid= 15649894 |doi= 10.1074/jbc.M410348200 |display-authors=etal}}
*{{cite journal | vauthors=Visser F, Baldwin SA, Isaac RE |title=Identification and mutational analysis of amino acid residues involved in dipyridamole interactions with human and Caenorhabditis elegans equilibrative nucleoside transporters. |journal=J. Biol. Chem. |volume=280 |issue= 12 |pages= 11025–34 |year= 2005 |pmid= 15649894 |doi= 10.1074/jbc.M410348200 |display-authors=etal}}
*{{cite journal | author=Owen RP, Lagpacan LL, Taylor TR |title=Functional characterization and haplotype analysis of polymorphisms in the human equilibrative nucleoside transporter, ENT2. |journal=Drug Metab. Dispos. |volume=34 |issue= 1 |pages= 12–5 |year= 2006 |pmid= 16214850 |doi= 10.1124/dmd.105.006270 |display-authors=etal}}
*{{cite journal | vauthors=Owen RP, Lagpacan LL, Taylor TR |title=Functional characterization and haplotype analysis of polymorphisms in the human equilibrative nucleoside transporter, ENT2. |journal=Drug Metab. Dispos. |volume=34 |issue= 1 |pages= 12–5 |year= 2006 |pmid= 16214850 |doi= 10.1124/dmd.105.006270 |display-authors=etal}}
}}
}}
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Revision as of 00:08, 23 May 2016

SLC29A2
Identifiers
AliasesSLC29A2, DER12, ENT2, HNP36, Equilibrative nucleoside transporter 2, solute carrier family 29 member 2
External IDsOMIM: 602110 MGI: 1345278 HomoloGene: 37493 GeneCards: SLC29A2
Orthologs
SpeciesHumanMouse
Entrez

3177

13340

Ensembl

ENSG00000174669

ENSMUSG00000024891

UniProt

Q14542

Q61672

RefSeq (mRNA)

NM_001300868
NM_001300869
NM_001532

NM_007854

RefSeq (protein)

NP_001287797
NP_001287798
NP_001523

NP_031880

Location (UCSC)Chr 11: 66.36 – 66.37 MbChr 19: 5.02 – 5.03 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Equilibrative nucleoside transporter 2 (ENT2) is a protein that in humans is encoded by the SLC29A2 gene.[5][6][7]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000174669 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024891 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Williams JB, Rexer B, Sirripurapu S, John S, Goldstein R, Phillips JA 3rd, Haley LL, Sait SN, Shows TB, Smith CM, Gerhard DS (Sep 1997). "The human HNP36 gene is localized to chromosome 11q13 and produces alternative transcripts that are not mutated in multiple endocrine neoplasia, type 1 (MEN I) syndrome". Genomics. 42 (2): 325–30. doi:10.1006/geno.1997.4751. PMID 9192854.
  6. ^ Crawford CR, Patel DH, Naeve C, Belt JA (Mar 1998). "Cloning of the human equilibrative, nitrobenzylmercaptopurine riboside (NBMPR)-insensitive nucleoside transporter ei by functional expression in a transport-deficient cell line". J Biol Chem. 273 (9): 5288–93. doi:10.1074/jbc.273.9.5288. PMID 9478986.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  7. ^ "Entrez Gene: SLC29A2 solute carrier family 29 (nucleoside transporters), member 2".

Further reading

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