Jeffrey I. Gordon
Jeffrey Ivan Gordon (* 1947 ) is an American microbiologist at Washington University in St. Louis .
Life
Gordon earned a bachelor's degree in biology from Oberlin College in 1969 and an MD from the University of Chicago in 1973 with a medical degree. He then worked as an assistant physician ( internal or Junior Assistant Resident ) at Barnes Hospital in St. Louis , Missouri , before he in 1975 as a research assistant at the Laboratory of Biochemistry of the National Cancer Institute changed (NCI), a facility of the National Institutes of Health ( NIH). 1978/1979 Gordon worked as an assistant doctor at Barnes Hospital (Senior Assistant Resident) and at the John Cochran VA Hospital (Chief Medical Resident) in St. Louis, before he went to the medical faculty of Washington University in 1979 as a lecturer (Fellow) .
In 1981 Gordon received his first professorship (assistant professor) at Washington University, in 1985 he became an associate professor , and in 1987 he was given a full professorship. From 1991 to 2004 he was head of the department for molecular biology and pharmacology , from 1994 to 2003 he was head of the overarching department for biology and biomedical sciences. Gordon has been director of the Institute for Genome Science and Systems Biology since 2004, and since 2008 he has also held a professorship for pathology and immunology .
Act
Gordon is considered a pioneer in interdisciplinary studies of the human microbiome , especially the intestine. He was able to make important contributions to the definition of the genomic and metabolic basis of the human microbiome and its importance for health and disease . Other works by Gordon deal with N-myristoylation , a process of post-translational modification of proteins.
He and his team found differences in the intestinal bacterial cultures in overweight people compared to normal weight people, both in humans and in mice. The microbial culture in overweight people was better at getting energy from food. In addition, when the culture was transferred from overweight to normal mice, it was found that these stored more fat. In obese people, especially the ratio of was Bacteroidetes (they include in particular the Bacteroides ) to Firmicutes shifted in favor of Firmicutes. The relative proportion of Bacteroidetes increased on diet. Gordon concluded that obesity has a bacterial component (he even speaks of an obesity epidemic).
In 2015 Thomson Reuters named him a favorite for a Nobel Prize in Physiology or Medicine .
Awards (selection)
- 1992 Fellow of the American Association for the Advancement of Science
- 2001 member of the National Academy of Sciences
- 2004 member of the American Academy of Arts and Sciences
- 2011 Honorary Doctorate from the University of Gothenburg
- 2013 Selman A. Waksman Award in Microbiology
- 2013 Robert Koch Prize
- 2014 Passano Award
- 2014 member of the American Philosophical Society
- 2014 Dickson Prize in Medicine
- 2014 Howard Taylor Ricketts Award and Honorary Doctorate from the University of Chicago
- 2015 König Faisal Prize for Medicine
- 2015 Keio Medical Science Prize
- 2016 Steven C. Beering Award, Indiana University
- 2017 Jacobaeus Prize, Novo Nordisk Foundation
- 2017 Massry Prize
- 2017 Louisa Gross Horwitz Prize
- 2018 Copley Medal
- 2018 BBVA Frontiers of Knowledge Award
Web links
- Gordon Lab and curriculum vitae at Washington University in St. Louis (wustl.edu)
Individual evidence
- ↑ Peter Turnbaugh, Ruth E. Ley , Michael A. Mahowald, Vincent Magrini, Elaine Mardis, Jeffrey I. Gordon: An obesity-associated gut microbiome with increased capacity for energy harves . In: Nature , Volume 444, 2006, pp. 1027-1031, abstract
- ↑ Ley, Turnbaugh, Klein, Gordon: Microbial ecology: human gut microbes associated with obesity . Nature, Vol. 444, 2006, p. 1022, PMID 17183309
- ↑ R. Ley, F. Bäckhed, P. Turnbaugh, C. Lozupone, R. Knight, J. Gordon Obesity age ecology microbial well . In: Proc. Nat. Acad. Sci. USA , Vol. 102, 2005, pp. 11070-11075, PMID 16033867
- ↑ Announcing the 2015 Citation Laureates , at Thomson Reuters.
- ↑ Jeffrey I. Gordon at the National Academy of Sciences (nasonline.org); Retrieved May 9, 2013
- ↑ Book of Members 1780 – present (PDF, 640 kB) of the American Academy of Arts and Sciences (www.amacad.org); Retrieved May 9, 2013
- ↑ https://www.gu.se/digitalAssets/1375/1375359_doktorspromotion2011.pdf#page=21
- ^ Selman A. Waksman Award in Microbiology from the National Academy of Sciences (nasonline.org); accessed on January 14, 2016
- ↑ Jeffrey Gordon at the Robert Koch Foundation (robert-koch-stiftung.de); Retrieved May 9, 2013
- ↑ Dr. Jeffrey I. Gordon at the American Philosophical Society (amphilsoc.org); Retrieved July 16, 2014
- ↑ 2014 Dickson Prize Winner at the University of Pittsburgh (pitt.edu); Retrieved July 16, 2014
- ↑ https://gordonlab.wustl.edu/JGCV_2017.html
- ↑ https://gordonlab.wustl.edu/JGCV_2017.html
- ↑ https://gordonlab.wustl.edu/JGCV_2017.html
- ↑ BBVA Frontiers of Knowledge Award 2018
personal data | |
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SURNAME | Gordon, Jeffrey I. |
ALTERNATIVE NAMES | Gordon, Jeffrey Ivan (full name) |
BRIEF DESCRIPTION | American microbiologist |
DATE OF BIRTH | 1947 |