Jeffrey I. Gordon

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Jeffrey Ivan Gordon (* 1947 ) is an American microbiologist at Washington University in St. Louis .

Life

Gordon earned a bachelor's degree in biology from Oberlin College in 1969 and an MD from the University of Chicago in 1973 with a medical degree. He then worked as an assistant physician ( internal or Junior Assistant Resident ) at Barnes Hospital in St. Louis , Missouri , before he in 1975 as a research assistant at the Laboratory of Biochemistry of the National Cancer Institute changed (NCI), a facility of the National Institutes of Health ( NIH). 1978/1979 Gordon worked as an assistant doctor at Barnes Hospital (Senior Assistant Resident) and at the John Cochran VA Hospital (Chief Medical Resident) in St. Louis, before he went to the medical faculty of Washington University in 1979 as a lecturer (Fellow) .

In 1981 Gordon received his first professorship (assistant professor) at Washington University, in 1985 he became an associate professor , and in 1987 he was given a full professorship. From 1991 to 2004 he was head of the department for molecular biology and pharmacology , from 1994 to 2003 he was head of the overarching department for biology and biomedical sciences. Gordon has been director of the Institute for Genome Science and Systems Biology since 2004, and since 2008 he has also held a professorship for pathology and immunology .

Act

Gordon is considered a pioneer in interdisciplinary studies of the human microbiome , especially the intestine. He was able to make important contributions to the definition of the genomic and metabolic basis of the human microbiome and its importance for health and disease . Other works by Gordon deal with N-myristoylation , a process of post-translational modification of proteins.

He and his team found differences in the intestinal bacterial cultures in overweight people compared to normal weight people, both in humans and in mice. The microbial culture in overweight people was better at getting energy from food. In addition, when the culture was transferred from overweight to normal mice, it was found that these stored more fat. In obese people, especially the ratio of was Bacteroidetes (they include in particular the Bacteroides ) to Firmicutes shifted in favor of Firmicutes. The relative proportion of Bacteroidetes increased on diet. Gordon concluded that obesity has a bacterial component (he even speaks of an obesity epidemic).

In 2015 Thomson Reuters named him a favorite for a Nobel Prize in Physiology or Medicine .

Awards (selection)

Web links

Individual evidence

  1. ↑ Peter Turnbaugh, Ruth E. Ley , Michael A. Mahowald, Vincent Magrini, Elaine Mardis, Jeffrey I. Gordon: An obesity-associated gut microbiome with increased capacity for energy harves . In: Nature , Volume 444, 2006, pp. 1027-1031, abstract
  2. ↑ Ley, Turnbaugh, Klein, Gordon: Microbial ecology: human gut microbes associated with obesity . Nature, Vol. 444, 2006, p. 1022, PMID 17183309
  3. ↑ R. Ley, F. Bäckhed, P. Turnbaugh, C. Lozupone, R. Knight, J. Gordon Obesity age ecology microbial well . In: Proc. Nat. Acad. Sci. USA , Vol. 102, 2005, pp. 11070-11075, PMID 16033867
  4. ↑ Announcing the 2015 Citation Laureates , at Thomson Reuters.
  5. ↑ Jeffrey I. Gordon at the National Academy of Sciences (nasonline.org); Retrieved May 9, 2013
  6. ↑ Book of Members 1780 – present (PDF, 640 kB) of the American Academy of Arts and Sciences (www.amacad.org); Retrieved May 9, 2013
  7. ↑ https://www.gu.se/digitalAssets/1375/1375359_doktorspromotion2011.pdf#page=21
  8. ^ Selman A. Waksman Award in Microbiology from the National Academy of Sciences (nasonline.org); accessed on January 14, 2016
  9. ↑ Jeffrey Gordon at the Robert Koch Foundation (robert-koch-stiftung.de); Retrieved May 9, 2013
  10. ↑ Dr. Jeffrey I. Gordon at the American Philosophical Society (amphilsoc.org); Retrieved July 16, 2014
  11. ↑ 2014 Dickson Prize Winner at the University of Pittsburgh (pitt.edu); Retrieved July 16, 2014
  12. ↑ https://gordonlab.wustl.edu/JGCV_2017.html
  13. ↑ https://gordonlab.wustl.edu/JGCV_2017.html
  14. ↑ https://gordonlab.wustl.edu/JGCV_2017.html
  15. ↑ BBVA Frontiers of Knowledge Award 2018
personal data
SURNAME Gordon, Jeffrey I.
ALTERNATIVE NAMES Gordon, Jeffrey Ivan (full name)
BRIEF DESCRIPTION American microbiologist
DATE OF BIRTH 1947