Van Lottum, whose older sister Noëlle played on the WTA Tour between 1987 and 1999 , became a professional tennis player in 1994. In his first two years as a professional he was only moderately successful on the lower-class satellite tour. In 1996 he reached a quarter-finals for the first time on the ATP Challenger Tour . The following year he made it to the quarterfinals of an ATP World Tour tournament in Amsterdam for the first time . In 1998 he came as a qualifier in the main draw in San José , where he surprisingly defeated Todd Martin on the way to the semi-finals before losing to Pete Sampras in three sets . 1999 was the best year of his career: he was in the semifinals in Madras and at the ATP International Series Gold tournament in Memphis and was also able to celebrate his first individual title on the ATP Challenger Tour in Ho Chi Minh City . Then in November he had to undergo knee surgery; In January 2000 he was able to resume his career and win his only double title with Jan Siemerink at the Challenger tournament in Heilbronn . By 2002 he won a total of five individual titles on the Challenger Tour, but he did not succeed in winning the title on the World Tour. He achieved the best scores in the world rankings in 1999 with position 62 in singles and in 2003 with position 232 in doubles.
Van Lottum played three singles and three doubles games for the Dutch Davis Cup team between 1988 and 2006 . While he could win two of the three doubles games, he lost all singles; including a game against Germany in the first round of the world group in 2000, when he lost to Tommy Haas and David Prinosil .
After the end of his professional career, he became a commentator for Eurosport .