Lewis C. Cantley
Lewis Clayton Cantley (born February 20, 1949 in Charleston , West Virginia ) is an American molecular biologist and biochemist .
Cantley graduated from Wesleyan College with a bachelor's degree in chemistry summa cum laude in 1971 and received his PhD in physical chemistry from Cornell University in 1975 , working with Gordon Hammes in enzyme kinetics. In 1978 he became an Assistant Professor and 1983 Associate Professor of Biochemistry and Molecular Biology at Harvard University . In 1985 he became Professor of Physiology at Tufts University School of Medicine. In 1992 he became Professor of Cell Biology at Harvard Medical School and Director of the Signal Transduction Department at Beth Israel Hospital . In 2003 he was one of the founders of the systems biology department at Harvard Medical School and in 2007 he became director of cancer research at Beth Israel. In 2012 he became director of the newly established Cancer Research Center at New York-Presbyterian Hospital and Weill Cornell Medical College .
In 1985, together with Malcolm Whitman, David Kaplan, Thomas M. Roberts and Brian Schaffhausen, he discovered the phosphoinositide 3-kinases as signal proteins. He also clarified the role of defects in their signaling pathway for cancer development and investigated their role in diabetes and autoimmune diseases.
In the mid-1990s, his laboratory also set up a database search service, for example to quickly find out the substrate specificity of protein kinases.
In 2000 he received the Heinrich Wieland Prize , the Rolf Luft Award in 2009 and the Pasarow Award in 2011 . In 2013 he was among the first to win the Breakthrough Prize in Life Sciences . In 2015 he received a Canada Gairdner International Award . For 2016, Cantley was awarded the Wolf Prize in Medicine. In 2019 he was awarded the Louisa Gross Horwitz Prize , in 2020 the Dr. Paul Janssen Award for Biomedical Research . He is an elected member of the National Academy of Sciences and, since 1999, the American Academy of Arts and Sciences . He has been a Fellow of the American Association for the Advancement of Science since 2011 . In 2015 he was elected as an associate member of the European Molecular Biology Organization . Since 2017, Clarivate Analytics has counted him among the favorites for a Nobel Prize in Physiology or Medicine ( Clarivate Citation Laureates , formerly Thomson Reuters Citation Laureates ) due to the number of his citations .
He is married to Harvard professor Vicki Sato .
Web links
Individual evidence
- ↑ Life data according to American Men and Women of Science , Thomson Gale 2004
- ↑ Whitman, Kaplan, Schaffhausen, Cantley, Roberts Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation , Nature, Volume 315, 1985, pp. 239-242, abstract
- ↑ Scan site
- ↑ https://www.aaas.org/news/aaas-members-elected-fellows-3
- ↑ The 2017 Clarivate Citation Laureates - Clarivate. (No longer available online.) In: clarivate.com. Archived from the original on September 20, 2017 ; accessed on September 21, 2017 . Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice.
| personal data | |
|---|---|
| SURNAME | Cantley, Lewis C. |
| ALTERNATIVE NAMES | Cantley, Lewis Clayton |
| BRIEF DESCRIPTION | American biochemist |
| DATE OF BIRTH | February 20, 1949 |
| PLACE OF BIRTH | Charleston , West Virginia , United States |