Jeffrey Ravetch

Jeffrey Victor Ravetch (born May 3, 1951 ) is an American immunologist at Rockefeller University in New York City .

Life

Ravetch grew up in New York City . He earned a bachelor's degree in molecular biophysics and biochemistry from Donald Crothers at Yale University in New Haven , Connecticut in 1973, and a Ph.D. in 1978 from Norton Zinder and Peter Model at Rockefeller University in New York City. in molecular genetics . He completed his medical studies in 1979 at Cornell University in Ithaca , New York , with an MD (professional doctorate). As a postdoctoral fellow , Ravetch worked with Philip Leder at the National Institute of Child Health and Human Development (NICHD) of the National Institutes of Health (NIH) in Bethesda , Maryland . Since 1982 he was a member of the faculty at Memorial Sloan-Kettering Cancer Center in New York City before he was made an assistant professor at Cornell University Medical College in 1986 . In 1996 Ravetch became a professor at Rockefeller University , where he is today (as of 2012) Theresa and Eugene M. Lang Professor of Molecular Genetics and Immunology .

Act

Ravetch's work helped shed light on how the Fc receptors act on the unchanging parts of antibodies , the Fc fragments. He was able to show how stimulating (stimulating) and inhibiting (inhibiting) Fc receptors determine the immune response . The aim of his research is to improve therapeutically used antibodies (for example in cancer immunotherapy ) or to reduce the damage caused by autoimmune diseases . Further work dealt with the genetics of Plasmodium falciparum , the causative agent of malaria .

Awards (selection)

2006 member of the National Academy of Sciences
2007 William B. Coley Award
2008 member of the American Academy of Arts and Sciences
2012 Canada Gairdner International Award
2015 Wolf Prize for Medicine
2017 Ross Prize
2018 Robert Koch Prize

literature

J. Ravetch: Profile of Jeffrey Ravetch. Interview by Philip Downey. In: Proceedings of the National Academy of Sciences . Volume 106, Number 19, May 2009, pp. 7689-7691, ISSN 1091-6490 . doi: 10.1073 / pnas.0903830106 . PMID 19416845 . PMC 2683121 (free full text).
Lynne Lederman: Profile of Jeffrey V. Ravetch, MD, Ph.D. In: BioTechniques. Volume 44, Number 2, February 2008, pp. 169-170

Web links

Jeffrey V. Ravetch, MD, Ph.D. at Rockefeller University (rockefeller.edu); Retrieved March 21, 2012

Individual evidence

↑ Curriculum Vitae (as of 1987) (PDF; 102 kB) at the University of California, San Francisco (ucsf.edu); Retrieved March 21, 2012
^ William B. Coley Award. In: cancerresearch.org. Retrieved January 24, 2016 .
↑ Book of Members 1780 – present, Chapter R. (PDF; 508 kB) In: American Academy of Arts and Sciences (amacad.org). Retrieved April 17, 2018 .
^ Jeffrey Ravetch - Gairdner Foundation. In: gairdner.org. Retrieved April 17, 2018 .
↑ Jeffrey V. Ravetch receives 2017 Ross Prize in Molecular Medicine - News . In: News . February 21, 2017 ( rockefeller.edu [accessed April 17, 2018]).

personal data
SURNAME	Ravetch, Jeffrey
ALTERNATIVE NAMES	Ravetch, Jeffrey V .; Ravetch, Jeffrey Victor (full name)
BRIEF DESCRIPTION	American immunologist at Rockefeller University in New York City
DATE OF BIRTH	May 3, 1951

[1] Curriculum Vitae (as of 1987) (PDF; 102 kB) at the University of California, San Francisco (ucsf.edu); Retrieved March 21, 2012

[2] William B. Coley Award. In: cancerresearch.org. Retrieved January 24, 2016 .

[3] Book of Members 1780 – present, Chapter R. (PDF; 508 kB) In: American Academy of Arts and Sciences (amacad.org). Retrieved April 17, 2018 .

[4] Jeffrey Ravetch - Gairdner Foundation. In: gairdner.org. Retrieved April 17, 2018 .

[5] Jeffrey V. Ravetch receives 2017 Ross Prize in Molecular Medicine - News . In: News . February 21, 2017 ( rockefeller.edu [accessed April 17, 2018]).