Judah Folkman

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Moses Judah Folkman (born February 24, 1933 in Cleveland , † January 14, 2008 in Denver ) was an American cell biologist and physician who was particularly known for his research on angiogenesis and the development of blood vessels .

Life

Judah Folkman graduated from Ohio State University and then from Harvard Medical School . After completing his studies, he worked at the Massachusetts General Hospital and did very successful research on liver cancer and the use of pacemakers .

From 1960 to 1962 Folkman served in the US Navy , studying blood vessel growth. In 1971 a publication appeared in the New England Journal of Medicine in which he presented his hypothesis that all forms of cancer are dependent on angiogenesis. This thesis was initially rejected and attacked by most of the experts, but has largely established itself in the course of the following years and further research. Folkman was subsequently considered a leading expert on angiogenesis , which opened up a wide range of medical applications for cancer control. The initial rejection of his thesis later turned into an overwhelming, almost exaggerated enthusiasm. In May 1998 James Watson said of Folkman that he could cure cancer in two years ( Judahs going to cure cancer in two years ), to which the latter replied ironically if you are a mouse, we can take very good care of you (for example: If they are a mouse we can take care of them very well).

Most recently, Folkman was Professor of Cell Biology at Harvard Medical School and Director of the Vascular Biology Program at the Children's Hospital in Boston. In 1986 he was elected to the American Academy of Arts and Sciences , in 1990 to the National Academy of Sciences and in 1999 to the American Philosophical Society . In 1991 he received a Gairdner Foundation International Award and in 1994 the Dr. Josef Steiner Cancer Research Prize . In 1997 he was awarded the Massry Prize and the Charles S. Mott Prize , the Keio Medical Science Prize in 1998 , the Pasarow Award in 2003 and the Prince of Asturias Prize in 2004 and the Warren Alpert Foundation Prize in 2005 .

Web links

Individual evidence

  1. ^ Folkman: Tumor Angiogenesis: Therapeutic Implications. In: New England Journal of Medicine . Volume 285, 1971, pp. 1182-1186, doi: 10.1056 / NEJM197111182852108 .
  2. Gina Colata: HOPE IN THE LAB: A special report .; A Cautious Awe Greets Drugs That Eradicate Tumors in Mice. In: nytimes.com. May 3, 1998, accessed January 1, 2020 .
  3. ^ G. Gasparini: Remembering Judah Moses Folkma. In: The International journal of biological markers. Volume 23, number 1, 2008 Jan - Mar, p. 63, doi : 10.5301 / JBM.2008.5002 , PMID 28207107 .
  4. ^ Member History: Judah Folkman. American Philosophical Society, accessed August 8, 2018 .