Tom Maniatis

from Wikipedia, the free encyclopedia

Tom Maniatis (actually Thomas Peter Maniatis ; born May 8, 1943 in Denver , Colorado ) is an American molecular biologist at Columbia University in New York City .

Life

Maniatis earned a bachelor's degree in biology and chemistry from the University of Colorado in 1965 and a master's degree in biology in 1967 . In 1971 he received a Ph.D. from Vanderbilt University. in molecular biology . As a postdoctoral fellow Maniatis worked with Mark Ptashne at Harvard University and with Fred Sanger in Cambridge , England.

In 1974 Maniatis received his first position as a research assistant at Harvard University in Cambridge , Massachusetts . In 1975 he became research group leader at the Cold Spring Harbor Laboratory on Long Island and an assistant professor of biochemistry and molecular biology at Harvard University. In 1977 he became an Associate Professor of Biology at the California Institute of Technology in Pasadena , California , and in 1979 he became a full professor there. 1981 Maniatis went back to Harvard University as professor of biochemistry and molecular biology, from 1985 to 1988 as head of the department. In 1995 he became Professor of Molecular and Cell Biology at Harvard .

In 2010 Maniatis moved to Columbia University in New York City , where he is now (as of 2012) head of the Department of Biochemistry and Molecular Biophysics .

Act

Maniatis was able to make fundamental contributions to the understanding of the structure and function of deoxyribonucleic acid (DNA), thereby laying the foundations for the development of techniques for artificial recombination of DNA ( genetic engineering ) and enabling new insights into the organization of the chromosomes of eukaryotes . His work on the genes of globins showed the different levels at which a regulation of gene expression takes place, which he the basis for studying the molecular causes of human hereditary diseases thought.

Maniatis' textbook Molecular cloning: a laboratory manual is considered a standard work in genetic engineering.

More recent work deals with the genetic causes of amyotrophic lateral sclerosis (ALS).

Awards (selection)

Web links

Individual evidence

  1. a b Dr. Tom Maniatis honored with the 2012 Lasker-Koshland Special Achievement Award in Medical Science at eurekalert.org; Retrieved September 11, 2012
  2. ^ Eli Lilly and Company-Elanco Research Award Past Laureates ( Memento November 13, 2012 in the Internet Archive ) at the American Society for Microbiology (asm.org).
  3. ^ Richard Lounsbery Award at the National Academy of Sciences (nasonline.org); Retrieved February 19, 2016
  4. Book of Members 1780 – present, Chapter M. (PDF; 1.1 MB) In: American Academy of Arts and Sciences (amacad.org). Retrieved May 19, 2019 .
  5. 2012 Lasker ~ Koshland Special Achievement Award in Medical Science at the Lasker Foundation (laskerfoundation.org); accessed on May 19, 2019.