Paul Chirik

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Paul J. Chirik (born June 13, 1973 in Philadelphia ) is an American chemist and currently Edwards S. Sanford Professor at Princeton University . He has specialized in organometallic chemistry , in particular in sustainable and environmentally friendly catalysis using elements that are common on earth .

Life

Paul Chirik received his bachelor's degree magna cum laude from the Virginia Polytechnic Institute and State University in 1995 , after working under Joseph Merola . His doctorate on the mechanism of metallocene- catalyzed olefin polymerization and hydrometalation in the group of John Bercaw at Caltech was awarded the Hebert Newby McCoy Award . After a brief postdoctoral stay with Christopher C. Cummins at the Massachusetts Institute of Technology , he joined Cornell University as an assistant professor in 2001 . In 2006 he was promoted to Associate Professor and in 2009 to Peter JW Debye Professor of Chemistry.

In the course of his career he has worked on over 180 scientific publications and is co-inventor of over 15 patents . He has also given lectures and lectures at over 200 national and international seminars and conferences. This included, for example, the Falling Walls Conference in Berlin in 2012 , where he gave a lecture on "Breaking the Wall of Sustainable Chemistry: How Modern Alchemy Can Lead to Inexpensive and Clean Technology".

He has also supervised over 30 doctoral students and 20 postdocs .

Since 2015 he has continued to serve as editor-in-chief of the American Chemical Society 's peer-reviewed journal Organometallics .

Research priorities

Chirik's research area can be classified between organic and inorganic chemistry and includes the development of sustainable methods in chemical synthesis. Among other things, the working group is researching the concept they call "modern alchemy ", in which the ligand design is chosen in such a way that the reactivity of frequently occurring metals mimics or even exceeds that of rare metals. One focus is on pharmaceutical and industry-relevant issues. In addition to synthesis methods, spectroscopic , physical and computational methods are also used. In addition, his group is investigating the functionalization of dinitrogen and the mutual conversion into ammonia .

Catalysis with common elements

Chirik's main field of research is catalysis with transition metals , which are common on Earth. Examples are iron and cobalt . The aim is to free the pharmaceutical and other industries from reliance on the scarce and expensive rare earth metals that are currently widely used. His group therefore developed redox-active ligands to adapt the electronic properties of transition metals of the fourth period in such a way that many-electron chemistry becomes possible. This concept of "metal-ligand cooperation", which has meanwhile been widely used, was popularized by Chirik, among others. This enabled him to develop suitable catalysts for the asymmetric hydrogenation , hydrosilylation and hydroboration of olefins based on iron and cobalt. These sometimes have higher activities and selectivities compared to their counterparts with rarer metals or can serve as catalysts for new types of cycloaddition reactions .

Furthermore, Chirik has developed catalysts based on common elements that work in a more traditional way, in which the electronic changes take place exclusively at the metal center. This enabled, among other things, catalysts for asymmetric hydrogenation, hydrogen isotope exchange reactions, C – H borylations and cross-coupling reactions to be carried out, which are of interest to the pharmaceutical industry.

Nitrogen functionalization and the mutual conversion of ammonia into its elements

Chirik is also researching the mutual conversion of ammonia (NH 3 ) and its constituent elements in the form of N 2 and H 2 . The forward reaction, in which nitrogen is converted into ammonia and other more valuable nitrogen-containing products, is now dependent on the Haber-Bosch process , which has a large ecological footprint and arouses an associated interest in alternatives. The reverse reaction, on the other hand, is based on the idea of ​​ammonia being used as a carbon-neutral fuel .

By means of homogeneous catalysis of early transition metals in a coordination sphere adapted to the problem, Chirik was able to develop new routes for the conversion of nitrogen into more valuable, nitrogen-containing organic compounds.

Using proton-coupled electron transfer, Chirik and his co-workers were also able to break down ammonia to form H 2 . He took advantage of the weakening of the N – H bond through coordination.

Honourings and prices

Web links

Individual evidence

  1. ^ A b c Communication from Cornell University. Cornell University, October 2001, accessed March 6, 2020 .
  2. ↑ a b c Paul Chirik | Princeton University Department of Chemistry .
  3. ↑ a b c The Chirik Group .
  4. ^ Merola Research Group - Organometallic Chemistry ● Catalysis ● Biological Activity. Retrieved February 29, 2020 (American English).
  5. ↑ Former Bercaw Group members. Retrieved February 29, 2020 .
  6. ↑ a b [1]
  7. ^ Falling Walls Foundation: Paul Chirik | Falling walls .
  8. ^ Organometallics welcomes new editor-in-chief: Paul Chirik, Ph.D. Retrieved February 29, 2020 .
  9. ↑ Paul Chirik To Lead Organometallics | Chemical & Engineering News. Retrieved February 29, 2020 .
  10. ↑ Paul Chirik (PhD '00) Named Editor of Organometallics. Retrieved February 29, 2020 (American English).
  11. ↑ Chirik named new editor-in-chief of Organometallics | Princeton University Department of Chemistry. Retrieved February 29, 2020 .
  12. ^ Non-innocent ligand . December 11, 2018.
  13. ↑ Sebastien Monfette, Zoë R. Turner, Scott P. Semproni, Paul J. Chirik: Enantiopure C 1 -Symmetric Bis (imino) pyridine Cobalt Complexes for Asymmetric Alkenes Hydrogenation . In: Journal of the American Chemical Society . tape 134 , no. 10 , March 14, 2012, ISSN  0002-7863 , p. 4561–4564 , doi : 10.1021 / ja300503k ( acs.org [accessed February 29, 2020]).
  14. ^ A b Suzanne C. Bart, Emil Lobkovsky, Paul J. Chirik: Preparation and Molecular and Electronic Structures of Iron (0) Dinitrogen and Silane Complexes and Their Application to Catalytic Hydrogenation and Hydrosilation . In: Journal of the American Chemical Society . 126, No. 42, October 1, 2004, pp. 13794-13807. doi : 10.1021 / ja046753t . PMID 15493939 .
  15. ↑ AM Tondreau, CCH Atienza, KJ Weller, SA Nye, KM Lewis: Iron Catalysts for Selective Anti-Markovnikov Alkenes Hydrosilylation Using Tertiary Silanes . In: Science . tape 335 , no. 6068 , February 3, 2012, ISSN  0036-8075 , p. 567-570 , doi : 10.1126 / science.1214451 ( sciencemag.org [accessed February 29, 2020]).
  16. ^ Hillary Rosner: Modern-Day Alchemy Has Iron Working Like Platinum . October 15, 2012.
  17. ↑ Jennifer V. Obligacion, Paul J. Chirik: Bis (imino) pyridine Cobalt-Catalyzed Alkenes Isomerization-Hydroboration: A Strategy for Remote Hydrofunctionalization with Terminal Selectivity . In: Journal of the American Chemical Society . tape 135 , no. 51 , December 26, 2013, ISSN  0002-7863 , p. 19107–19110 , doi : 10.1021 / ja4108148 ( acs.org [accessed February 29, 2020]).
  18. ^ Sarah K. Russell, Emil Lobkovsky, Paul J. Chirik: Iron-Catalyzed Intermolecular [ 2π + 2π ] cycloaddition . In: Journal of the American Chemical Society . tape 133 , no. 23 , June 15, 2011, ISSN  0002-7863 , p. 8858-8861 , doi : 10.1021 / ja202992p ( acs.org [accessed February 29, 2020]).
  19. ↑ JM Hoyt, VA Schmidt, AM Tondreau, PJ Chirik: Iron-catalyzed intermolecular [2 + 2] cycloadditions of unactivated alkenes . In: Science . tape 349 , no. 6251 , August 28, 2015, ISSN  0036-8075 , p. 960–963 , doi : 10.1126 / science.aac7440 ( sciencemag.org [accessed February 29, 2020]).
  20. ↑ MR Friedfeld, M. Shevlin, JM Hoyt, SW Krska, MT Tudge: cobalt precursor for high-throughput discovery of Base Metal Asymmetric Hydrogenation Catalysts alkenes . In: Science . tape 342 , no. 6162 , November 29, 2013, ISSN  0036-8075 , p. 1076-1080 , doi : 10.1126 / science.1243550 ( sciencemag.org [accessed February 29, 2020]).
  21. ^ Stu Borman: Catalysts That Are Less Precious | December 16, 2013 Issue - Vol. 91 Issue 50 | Chemical & Engineering News. Retrieved February 29, 2020 .
  22. ↑ Max R. Friedfeld, Hongyu Zhong, Rebecca T. Ruck, Michael Shevlin, Paul J. Chirik: cobalt-catalyzed asymmetric hydrogenation of enamides enabled by single-electron reduction . In: Science . tape 360 , no. 6391 , May 25, 2018, ISSN  0036-8075 , p. 888–893 , doi : 10.1126 / science.aar6117 ( sciencemag.org [accessed February 29, 2020]).
  23. ↑ Renyuan Pony Yu, David Hesk, Nelo Rivera, István Pelczer, Paul J. Chirik: Iron-catalysed tritiation of pharmaceuticals . In: Nature . tape 529 , no. 7585 , January 2016, ISSN  0028-0836 , p. 195–199 , doi : 10.1038 / nature16464 ( nature.com [accessed February 29, 2020]).
  24. ↑ 'Radiolabeling' lets scientists track the breakdown of drugs | Princeton University Department of Chemistry. Retrieved February 29, 2020 .
  25. ↑ Jennifer V. Obligacion, Scott P. Semproni, Paul J. Chirik: Cobalt-Catalyzed C – H Borylation . In: Journal of the American Chemical Society . tape 136 , no. 11 , March 19, 2014, ISSN  0002-7863 , p. 4133-4136 , doi : 10.1021 / ja500712z ( acs.org [accessed February 29, 2020]).
  26. ↑ Jamie M. Neely, Máté J. Bezdek, Paul J. Chirik: Insight into Transmetalation Enables Cobalt-Catalyzed Suzuki – Miyaura Cross Coupling . In: ACS Central Science . tape 2 , no. 12 , December 28, 2016, ISSN  2374-7943 , p. 935-942 , doi : 10.1021 / acscentsci.6b00283 , PMID 28058283 , PMC 5200927 (free full text) - ( acs.org [accessed February 29, 2020]).
  27. ↑ Asbjørn Klerke, Claus Hviid Christensen, Jens K. Nørskov, Tejs Vegge: Ammonia for hydrogen storage: challenges and opportunities . In: Journal of Materials Chemistry . tape 18 , no. 20 , 2008, ISSN  0959-9428 , p. 2304 , doi : 10.1039 / b720020j ( rsc.org [accessed February 29, 2020]).
  28. ↑ CU researchers find a long-sought method for fixing nitrogen. Retrieved February 29, 2020 .
  29. ↑ 'Remarkable chemical transformation,' new method for converting nitrogen to ammonia, is discovered by Cornell researchers. Retrieved February 29, 2020 .
  30. ↑ Chemists make nitrogen-carbon bonds but skip the ammonia. Retrieved February 29, 2020 .
  31. ↑ Donald J. Knobloch, Emil Lobkovsky, Paul J. Chirik: Dinitrogen cleavage and functionalization by carbon monoxide promoted by a hafnium complex . In: Nature Chemistry . tape 2 , no. 1 , January 2010, ISSN  1755-4330 , p. 30–35 , doi : 10.1038 / nchem.477 ( nature.com [accessed February 29, 2020]).
  32. ^ Scott P. Semproni, Paul J. Chirik: Synthesis of a Base-Free Hafnium Nitride from N 2 Cleavage: A Versatile Platform for Dinitrogen Functionalization . In: Journal of the American Chemical Society . tape 135 , no. 30 , July 31, 2013, ISSN  0002-7863 , p. 11373–11383 , doi : 10.1021 / ja405477m ( acs.org [accessed February 29, 2020]).
  33. ↑ Iraklis Pappas, Paul J. Chirik: Ammonia Synthesis by Hydrogenolysis of Titanium-Nitrogen Bonds Using Proton Coupled Electron Transfer . In: Journal of the American Chemical Society . tape 137 , no. 10 , March 18, 2015, ISSN  0002-7863 , p. 3498-3501 , doi : 10.1021 / jacs.5b01047 ( acs.org [accessed February 29, 2020]).
  34. ↑ Máté J. Bezdek, Sheng Guo, Paul J. Chirik: Coordination-induced weakening of ammonia, water, and hydrazine X-H bonds in a molybdenum complex . In: Science . tape 354 , no. 6313 , November 11, 2016, ISSN  0036-8075 , p. 730–733 , doi : 10.1126 / science.aag0246 ( sciencemag.org [accessed February 29, 2020]).
  35. ^ Grant W. Margulieux, Máté J. Bezdek, Zoë R. Turner, Paul J. Chirik: Ammonia Activation, H 2 Evolution and Nitride Formation from a Molybdenum Complex with a Chemically and Redox Noninnocent Ligand . In: Journal of the American Chemical Society . tape 139 , no. 17 , May 3, 2017, ISSN  0002-7863 , p. 6110-6113 , doi : 10.1021 / jacs.7b03070 ( acs.org [accessed February 29, 2020]).
  36. ↑ ACS 2021 national award winners. Retrieved August 22, 2020 (English).
  37. ↑ Chirik Wins ACS Catalysis Award | Princeton University Department of Chemistry. Retrieved August 22, 2020 .
  38. ↑ Awards - ORCS. Retrieved March 1, 2020 (American English).
  39. ↑ CHEM News and Events Distinguished Lectureship Series. Retrieved March 1, 2020 .
  40. ↑ Congratulations to the 2017 ACS Catalysis Lectureship Recipient: Professor Paul Chirik. In: ACS Axial. August 15, 2017, Retrieved March 1, 2020 (American English).
  41. ↑ OCSPP US EPA: Presidential Green Chemistry Challenge: 2016 Academic Award . June 7, 2016.
  42. ↑ Awardees of JSCC International Awards for Creative Work | 錯 体 化学 会 Japan Society of Coordination Chemistry. Retrieved March 1, 2020 (Japanese).
  43. ↑ Paul Chirik presents Dalton Transactions Americas Lecture in Berkeley “Dalton Transactions Blog says: Paul Chirik awarded 2010 Dalton Transactions Americas Lectureship - Dalton Transactions Blog. Retrieved March 1, 2020 (American English).
  44. ↑ Paul Chirik | Blavatnik Awards for Young Scientists .
  45. ↑ Paul Chirik: Arthur C. Cope Scholar Awardee | March 9, 2009 Issue - Vol. 87 Issue 10 | Chemical & Engineering News .
  46. ^ Dreyfus Foundation | Dedicated to the advancement of the chemical sciences .
  47. ^ Russell Distinguished Teaching Award | Cornell University College of Arts and Sciences Cornell Arts & Sciences. Retrieved March 1, 2020 .
  48. ↑ Chirik, Paul J. .
  49. ↑ Cornell's Paul Chirik wins national research award .
personal data
SURNAME Chirik, Paul
ALTERNATIVE NAMES Chirik, Paul J.
BRIEF DESCRIPTION American chemist
DATE OF BIRTH June 13, 1973
PLACE OF BIRTH Philadelphia