Arnold J. Levine

from Wikipedia, the free encyclopedia

Arnold Jay Levine (born July 30, 1939 in Brooklyn , New York ) is an American biologist and cancer researcher .

Life

Levine acquired in 1961 at Harpur College of Binghamton University in Binghamton , New York , a Bachelor in Biology . In 1966 he earned with a thesis on "the role of the structural proteins of adenoviruses in ending the biosynthesis of the host cell " at the University of Pennsylvania in Philadelphia , Pennsylvania , a Ph.D. in microbiology . As a postdoctoral fellow , Levine went to the California Institute of Technology (Caltech) and worked on the DNA replication of Phi X 174 , a bacteriophage .

Levine then received a first junior professorship ( Assistant Professor 1968, Associate Professor 1973) for biochemistry at Princeton University in Princeton , New Jersey , and in 1976 a full professorship. In 1979 he became Professor of Microbiology and Director of the Institute at Stony Brook University in Stony Brook , New York . In 1984 Levine returned to Princeton University as Professor of Molecular Biology and Head of Institute. In 1998 he was a professor of tumor biology ( "Cancer Biology") at the Rockefeller University in New York City ; at the same time he was president of the university. Since 2003 Levine has been Professor of Biochemistry and Pediatrics at Robert Wood Johnson Medical School (a university affiliated with the University of Medicine and Dentistry of New Jersey ) in Piscataway and New Brunswick , both in New Jersey.

Since 2003 Levine has also worked at the Institute for Advanced Study in Princeton , New Jersey , a well-known private research institution - initially as a visiting professor and since 2004 as a full professor. There he heads the Simons Center for Systems Biology .

Levine is married and has two daughters.

Act

Levine is one of the researchers who made decisive contributions to clarifying the meaning of p53 . The protein p53 plays a special role in cell division , as an important tumor suppressor and possibly in aging processes . Levine was able to show that p53 is able to prevent the oncogenes- promoted conversion of healthy cells into cancer cells . His work is fundamental to the understanding of oncogenesis (the development of cancer) and opened up new possibilities for the prevention, detection and treatment of cancer.

Levine's other merits are AIDS research. In 1996 he chaired a panel of experts that was convened to control US federal research funding.

Awards (selection)

Web links

Individual evidence

  1. American Men & Women of Science, A biographical directory of today's leaders in physical, biological and related sciences. 21st Edition, Volume 4, Bowker 2009, ISBN 978-1-4144-3304-2 , p. 769.
  2. a b c Arnold J. Levine Named President of Rockefeller University at rockefeller.edu; Retrieved January 6, 2011
  3. ^ Arnold J. Levine at the Institute for Advanced Study ; Retrieved January 6, 2011
  4. ^ Prestigious Horwitz Prize Awarded to Pioneers in Molecular Biology In: The Reporter. Columbia University 04/1999. ( Memento from August 18, 2014 in the Internet Archive )
  5. ^ Charles Rodolphe Brupbacher Prize. Retrieved August 24, 2019 .
  6. 1993 8. Dr. Josef Steiner Cancer Research Prize at the University of Bern (unibe.ch); Retrieved April 26, 2012
  7. ^ Past Recipients of the Louisa Gross Horwitz Prize at columbia.edu; Retrieved January 6, 2011
  8. ^ Goethe University - laureate since 1952. In: uni-frankfurt.de. March 14, 2016, accessed January 23, 2016 .
  9. ^ Member History: Arnold J. Levine. American Philosophical Society, accessed February 2, 2019 .
  10. ^ Albany Medical College: 2001. In: amc.edu. March 2011, accessed on January 23, 2016 .