Friedrich Reinke

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Friedrich Reinke at the age of 24
Reinke's signature

Friedrich Berthold Reinke (born April 11, 1862 in Ziethen ; † May 12, 1919 in Wiesbaden ) was a German physician , pathologist and university professor.

Friedrich Reinke (right) with his older brother Johannes Reinke

Live and act

Friedrich Reinke came from a pastor family. He was the ninth of ten children of Pastor Theodor (Friedrich Julius) Reinke and his wife (Henriette Karoline Gottfriede Juliane) Elisabeth, geb. Kämffer (1821–1880), born in Ziethen (then the Duchy of Saxony-Lauenburg ). The botanist Johannes Reinke was his brother; a close friend of the later doctoral advisor of Friedrich Reinke the anatomist and cell biologist Walther Flemming .

Reinke spent his childhood mainly in Alt Käbelich ( Grand Duchy of Mecklenburg-Strelitz ), where his father had been a pastor since 1864. Up to the age of fourteen he received school lessons in a home environment , mainly from his father and an aunt. Later, he attended the School Carolinum in Neustrelitz , in 1882 he moved to Rostock , where he attended the 1883 Great City School Rostock his High School graduated.

Reinke began in 1883 at the Georg-August-Universität Göttingen and continued his medical studies at the Christian-Albrechts-Universität zu Kiel , which he finished on August 13, 1890 with a license to practice medicine . His dissertation was "Investigations into the relationship between the core forms described by Arnold and mitosis and amitosis" with which Reinke received his doctorate on March 28, 1891. From 1886 to 1901 he was employed as an assistant at the Physiological Institute of the University of Göttingen. This was followed by a six-month internship at the Institute for Pathology at the University of Zurich , where Edwin Klebs accompanied his studies . Reinke developed a friendly relationship with Otto Lubarsch , who was an assistant at the institute at the time. After completing his internship, Reinke worked as a ship's doctor from 1891 to 1892 on his voyage on the HAPAG passenger ship “Wieland”. a. to Porto Alegre ( Brazil ). There he made contact with family members who had emigrated .

He returned to Germany in 1892 to practice as a general practitioner on the manor Dahmen ( Grand Duchy of Mecklenburg-Schwerin ). In 1893 the professor of anatomy Albert von Brunn (1849–1895) offered him a position as the first demonstrator at the Anatomical Institute of the University of Rostock . Here he also wrote his habilitation with the title "Cell Studies". In this habilitation thesis from 1893, he carried out investigations into the cell structure in the germinal layer of human skin . From 1893 to 1900 he was a private lecturer and from October 9, 1900 to 1908, he was an associate professor of medicine and anatomy at the University of Rostock.

On Tuesday, August 12, 1902, Reinke married Julie Caroline Friederike Auguste von Zülow (1869–1942). On May 2, 1904, she gave birth to their only child, Hans Gebhard Reinke, who later became a theologian. Their son was baptized on August 3, 1904 in the Nikolaikirche in Rostock.

Group picture with Friedrich Reinke (arrow) from 1904
Section through the human vocal cord from a work by Friedrich Reinke (1897)

In 1896 Dietrich Barfurth was appointed professor of anatomy and director of the anatomical institute at the University of Rostock, and since 1889 he was professor of comparative anatomy , histology and embryology at the University of Dorpat . The relationship between Barfurth and Reinke was tense. In 1908 Reinke moved to Wiesbaden, where he worked as a demonstrator at the Pathological Institute of the Wiesbaden Municipal Hospital under Professor Gotthold Herxheimer and continued his research on cell division . Herxheimer was director of the pathological-anatomical institute at the municipal hospital in Wiesbaden.

Friedrich Berthold Reinke died on Monday, May 12, 1919 in the Paulinenstift in Wiesbaden of complications from gastric cancer .

Two anatomical structures named after Friedrich Reinke are the "Reinke crystals" of the testicle and the "Reinke space" in the area of ​​the vocal cords. In 1895 he described in detail the histological structure of a testicle specimen from a 25-year-old executed man . They were referred to as so-called "Reinke crystals" and are intracellular rod-shaped or wedge-shaped, crystalline aggregates of globular proteins that occur in the cytoplasm of the Leydig cells in the human testis.

The " Reinke edema " was first described in 1891 by M. Hajek from Vienna. Reinke examined this change and described the "Reinke space" as a subepithelial displacement gap in the narrow lamina propria mucosae in the plica vocalis . It is this space that enables the vocal cord epithelium above it to vibrate better during phonation . He was able to prove this tissue layer or its delimitation by injecting glycerol glue and air and the subsequent microscopic assessment.

In addition to the descriptive and comparative anatomy, he was particularly interested in the (histological) investigation of the processes involved in cell division .

Works (selection)

  • Investigations into the relationship between the core forms described by Arnold and mitosis and amitosis. Dissertation, University of Kiel, Kiel (1891)
  • Cell studies. Habilitation thesis, University of Rostock (1893)
  • About crystalloid formations in the interstitial cells of the human testicle. (1896).
  • About the functional structure of the human vocal folds with special consideration of the elastic tissue. Bergmann, Wiesbaden 1897.
  • Short textbook on human anatomy for students and doctors with the most precise consideration of the Basel anatomical nomenclature. (1899)
  • Basics of general anatomy: To prepare for studying medicine; processed according to biological criteria. Wiesbaden 1901.
  • Experimental research on mammals on the creation of artificial blastomas. (1913).
  • Experimental studies on the proliferation and further development of leukocytes. Contribution z. path. Anatomie, V, 3, p. 439
  • Studies on the human vocal cord. Advances in Medicine, Munich, 1895, 13: 469–478.
  • About a few experiments with Lysol on fresh tissues to illustrate histological details. (1893)
  • About some other results of the lysol effect on fresh tissues to illustrate histological details. (1893)
  • The Japanese method of sticking paraffin sections. (1895)
  • Studies on the fertilization and cleavage of the egg of the echinoderms. (1895)
  • The quantitative and qualitative effect of the etheric lymph on the growth of the brain of the salamander larva. (1907)
  • About driving and inhibiting mitotic cell division in normal and pathological tissue growth. (1907)
  • About methods of acting on mitotic nucleus and cell division. (1907)

literature

  • Désirée Louise Dräger: Friedrich Berthold Reinke (1862–1919). A biographical and bibliographical review of his life and his most important scientific works. Südwestdeutscher Verlag für Hochschulschriften, 2014, ISBN 978-3-8381-3850-3
  • Uta Dreschke: Biography and scientific work of the prosectors of the Anatomical Institute Rostock from 1853-1945. Rostock 1969.
  • Gustav Willgeroth : The Mecklenburg doctors from the oldest times to the present. Schwerin 1929, pp. 280-281.
  • DL Dräger, C. Protzel, OW Hakenberg: Rostock anatomist and descriptor of the Reinke crystals of the testicle and the Reinke space of the larynx. The urologist 8/2014
  • Désirée Louise Dräger, Ryan C. Branski, Andreas Wree, Lucian Sulica: Friedrich Berthold Reinke (1862–1919): Anatomist of the Vocal Fold. Journal of Voice, 21 May 2010, 25/3, pp. 301–307 [5]

Web links

Commons : Friedrich Berthold Reinke  - Collection of images, videos and audio files

Individual evidence

  1. ^ Regional Church Archives of the Evangelical Lutheran North Church, Church Book Office Schwerin, Reg.-No .: 5320.
  2. ^ Association for Mecklenburg Family and Personal History eV [1]
  3. ↑ DL Dräger, C. Protzel, OW Hakenberg: Rostock anatomist and descriptor of the Reinke crystals of the testicle and the Reinke space of the larynx. The Urologist 8/2014, p. 1209
  4. ↑ Illustration of the secondary school leaving certificate of the large city school Rostock [2]
  5. ↑ August Blanck , Axel Wilhelmi : The Mecklenburg doctors from the oldest times to the present with brief information about their life and their writings Mecklenburgischer Ärztevereinsbund. Eduard Herbergers, Schwerin 1929, p. 235 [3]
  6. ↑ 3497 BRT A. Stephen & Sons 1875: Adler line / 1875 to HAPAG , sold in 1895 and burned out; the ship's name is occasionally given as "Weiland", but such a ship did not exist in the context described.
  7. ^ Entry on Friedrich Berthold Reinke in the Catalogus Professorum Rostochiensium
  8. ^ Association for Mecklenburg Family and Personal History ev, www.emecklenburg.de [4]
  9. ↑ M. Hajek: Anatomical studies on the laryngeal edema. In: Langenbecks Arch Chir. 42 (1891), pp. 46-93.
  10. ↑ Otto Bachmann: Guide to the preparation of microscopic permanent slides. R. Oldenbourg, Munich / Leipzig 1893, p. 53
personal data
SURNAME Reinke, Friedrich
ALTERNATIVE NAMES Reinke, Friedrich Berthold (full name)
BRIEF DESCRIPTION German physician, anatomist, pathologist, university professor
DATE OF BIRTH April 11, 1862
PLACE OF BIRTH Ziethen
DATE OF DEATH May 12, 1919
Place of death Wiesbaden