James E. Darnell
James Edwin Darnell, Jr. (born September 9, 1930 in Columbus , Mississippi ) is an American cell biologist and professor at Rockefeller University in New York City .
Life
Darnell earned an MD from Washington University in St. Louis , Missouri , in 1955 ; He carried out his first research on the poliovirus with Harry Eagle at the National Institute of Allergy and Infectious Diseases , a facility of the National Institutes of Health , and further research with François Jacob at the Pasteur Institute in Paris . Academic positions have taken him to the Massachusetts Institute of Technology in Cambridge , Massachusetts , the Albert Einstein College of Medicine in New York City and Columbia University , also in New York City. In 1974 he took over a professorship in cell biology at Rockefeller University in New York City.
Act
Darnell's research focuses on signal transduction and virus replication . In 1962/1963 Darnell provided the first evidence of RNA processing , in 1971 he and his colleagues were able to define events that lead to the formation of mRNA , rRNA and tRNA . Discovered the JAK-STAT signaling pathway between the cell surface and the nucleus . He used interferons as a model cytokine .
Darnell is considered to be a sponsor of young scientists. He was able to establish numerous junior professorships at his college, Rockefeller University, many of these junior professors later received full professorships or other lifetime positions .
Since 2014 Thomson Reuters has counted him among the favorites for a Nobel Prize ( Thomson Reuters Citation Laureates ) due to the number of his citations .
Awards (selection)
- 1973 member of the American Academy of Arts and Sciences
- 1973 membership in the National Academy of Sciences
- 1979 Howard Taylor Ricketts Award
- 1986 Gairdner Foundation International Award
- 1994 Keith R. Porter Lecture
- 1996 Foreign member of the Royal Society
- 1997 Passano Award
- 1998 EB Wilson Medal
- 1999 Dickson Prize in Medicine
- 1999 William B. Coley Award
- 2002 National Medal of Science
- 2002 Albert Lasker Special Achievement Award
- 2004 Foreign member of the Royal Swedish Academy of Sciences
- 2012 Albany Medical Center Prize
- 2013 member of the American Philosophical Society
Web links
- James E. Darnell, MD and James E. Darnell, Jr. MD Laboratory of Cell Biology at Rockefeller University (rockefeller.edu); Retrieved February 14, 2011
Individual evidence
- ↑ 2014 Predictions at Thomson Reuters (sciencewatch.com); Retrieved September 25, 2014
- ↑ Book of Members 1780 – present, Chapter D. (PDF; 575 kB) In: American Academy of Arts and Sciences (amacad.org). Retrieved April 16, 2018 .
- ↑ James E. Darnell MD at gairdner.org; Retrieved December 8, 2012
- ↑ Foreign Members in royalsociety.org; Retrieved February 13, 2011
- ^ The Passano Awards 1945–2009 at passanofoundation.org; Retrieved February 13, 2011
- ^ Dickson Prize in Medicine Winners at dicksonprize.pitt.edu; Retrieved February 13, 2011
- ^ William B. Coley Award. In: cancerresearch.org. Retrieved January 24, 2016 .
- ↑ Laureates of the 2002 National Medal of Science and James E. Darnell at nsf.gov; Retrieved February 13, 2011
- ↑ Lasker Foundation: RNA processing and cytokine signaling. In: laskerfoundation.org. Retrieved April 16, 2018 .
- ^ New foreign members of the Academy at kva.se; Retrieved February 13, 2011
- ^ Albany Medical College: 2012. In: amc.edu. March 2011, accessed January 31, 2016 .
| personal data | |
|---|---|
| SURNAME | Darnell, James E. |
| ALTERNATIVE NAMES | Darnell, James Edwin Jr. |
| BRIEF DESCRIPTION | American cell biologist |
| DATE OF BIRTH | September 9, 1930 |
| PLACE OF BIRTH | Columbus , Mississippi |