Steven Ley

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Steven Victor Ley (born December 10, 1945 in Stamford , Lincolnshire , England ) is a British chemist.

Live and act

Steven Victor Ley was the son of Mary Ley, b. Hall, and born Ralph Gilbert Ley. He studied at Loughborough University , where he received his Bachelor and Diploma in Industrial Studies in 1969 . In 1972, he was there with Harry Heaney with a thesis on didehydrobenzene ( Benzyn ) for Ph. D. doctorate . He then worked as a post-doctoral student with Leo A. Paquette at Ohio State University on homoaromaticity in new hydrocarbons . In 1974 he returned to England to work with Derek Barton at Imperial College London . From 1975 to 1983 he was a lecturer there . After his promotion to Doctor of Science, he was from 1983 to 1992 Professor of Organic Chemistry from 1989 to 1992 Head of the Chemistry Department. Since 1992 he has been Professor of Organic Chemistry at Trinity College of the University of Cambridge , where he graduated in 1997 with a Master of Arts in 1999 and a Scientific Doctor received. Visiting professorships took him to the University of Queensland in 1985 , to the Swiss Federal Institute of Technology in Zurich in 1988, to St Andrews University several times from 1994 to 2004 , to the University of Salamanca in 1996, to Texas A&M University in 1996 , to the University of Florida in 2001 , 2002 the University of Milan and in 2003 the University of Pavia .

Ley works in the field of organic chemistry . He synthesized more than 120 complex natural products and developed new organic molecules, for example new starting materials for organic synthesis such as TBAP and TPAP . He also used microbial oxidation by the bacterium Pseudomonas putida to represent important biologically active molecules and researches protective groups and organocatalysis . In 2006, his group succeeded for the first time in the total synthesis of a natural product with several flow reactors (i.e. within the framework of flow chemistry ).

He has been married to Rosemary Ann Jamesson since 1970, with whom he has a daughter. He finds relaxation while skiing and at the opera .

Awards

Honorary doctorates

1994 Loughborough University , 2000 University of Salamanca , 2003 University of Huddersfield

Memberships

Publications

Ley has published more than 650 publications, including the following books:

  • Steven V. Ley and Caroline MR Low: Ultrasound in synthesis (= Reactivity and structure, Volume 27). Springer, Berlin [a. a.] 1989, ISBN 3-540-51023-0
  • as editor: Comprehensive organic synthesis. Selectivity, strategy and efficiency in modern organic chemistry . Volume 7 Oxidation . Pergamon Press, Oxford 1991, ISBN 0-08-040598-3
  • as editor: Comprehensive organic functional group transformations . Volume 2 Synthesis. Carbon with one heteroatom attached by a single bond . Pergamon, Oxford 1995, ISBN 0-08-042323-X
  • Sweet Dreams. New strategies and methods for complex oligosaccharide assembly (= Schering lecture, Volume 37). Ernst Schering Research Foundation, Berlin 2000

literature

Web links

Individual evidence

  1. ↑ The life data, publications and academic family tree of Steven Victor Ley at academictree.org, accessed on March 8, 2018.
  2. ↑ see for example: DM Hollinshead, SC Howell, SV Ley, M. Mahon, NM Ratcliffe and PA Worthington: The Diels-Adler route to drimane related sesquiterpenes. Synthesis of cinnamolide, polygodial, isodrimeninol, drimenin and warburganal . In: Journal of the Chemical Society, Perkin Transactions. Volume 1, No. 7, 1983, pp. 1579-1589; MP Edwards, SV Ley, SG Lister and BD Palmer: Total Synthesis of the structural unique ionophore antibiotic X-1457 A. In: Journal of the Chemical Society . Volume 11, 1983, pp. 630-633.
  3. ^ WP Griffith, SV Ley, GP Whitcombe, AD White: Preparation and use of tetra-n-butylammonium (TBAP reagent) and tetra-n-propylammonium per-ruthenate (TPAP reagent) as new catalytic oxidants for alcohols . In: J. Chem. Soc., Chem. Commun. Volume 21, 1987, pp. 1625-1627; doi: 10.1039 / C39870001625 .
  4. ^ SV Ley, F. Sternfeld and S. Taylor: Microbial exidation in synthesis. A six step preparation of (±) -pinitol from benzene . In: Tetrahedr. Lett. Volume 28, No. 2, 1987, pp. 225-230.
  5. ↑ Derek Lowe, Das Chemiebuch, Librero 2017, p. 498
  6. ^ Heinrich Wieland Prize Laureates 2000–2009
personal data
SURNAME Ley, Steven
ALTERNATIVE NAMES Ley, Steven Victor (full name)
BRIEF DESCRIPTION British chemist
DATE OF BIRTH December 10, 1945
PLACE OF BIRTH Stamford , Lincolnshire , England